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Breast Cancer Research
Published in: Breast Cancer Research 5/2003

Open Access 01-10-2003 | Research article

Breast cancer in association with thyroid disorders

Authors: Orhan Turken, Yavuz NarIn, Sezai DemIrbas, M Emin Onde, Ozkan Sayan, E Gokhan KandemIr, Mustafa YaylacI, Ahmet Ozturk

Published in: Breast Cancer Research | Issue 5/2003

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Abstract

Background

The relationship between breast cancer and thyroid diseases is controversial. Discrepant results have been reported in the literature. The incidences of autoimmune and nonautoimmune thyroid diseases were investigated in patients with breast cancer and age-matched control individuals without breast or thyroid disease.

Methods

Clinical and ultrasound evaluation of thyroid gland, determination of serum thyroid hormone and antibody levels, and fine-needle aspiration of thyroid gland were performed in 150 breast cancer patients and 100 control individuals.

Results

The mean values for anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than in control individuals (P = 0.030). The incidences of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than in control individuals (38% versus 17%, P = 0.001; 26% versus 9%, P = 0.001, respectively).

Conclusion

Our results indicate an increased prevalence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients.
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Metadata
Title
Breast cancer in association with thyroid disorders
Authors
Orhan Turken
Yavuz NarIn
Sezai DemIrbas
M Emin Onde
Ozkan Sayan
E Gokhan KandemIr
Mustafa YaylacI
Ahmet Ozturk
Publication date
01-10-2003
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue 5/2003
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr609

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