Top

Published in:

01-05-2008 | Poster presentation

Actions of IGF-I are differentially regulated by fatty acids in normal and breast cancer epithelial cells

Authors: CM Perks, AA Morrison, L Zeng, C Jarrett, J Shield, ZE Winters, JMP Holly

Published in: Breast Cancer Research | Special Issue 2/2008

Excerpt

Obesity will soon be the leading preventable risk factor for many cancers. The insulin-like growth factors (IGFs) have been strongly implicated as important risk factors for many epithelial cancers, including breast cancer, and for mediating the link between nutrition and these cancers. Obesity-related increases in circulating fatty acids cause insulin resistance with consequent morbidity but, despite the considerable overlap between insulin and IGFs, there have been no studies of the effects of fatty acids on IGF activity. …

Title: Actions of IGF-I are differentially regulated by fatty acids in normal and breast cancer epithelial cells
Authors: CM Perks
AA Morrison
L Zeng
C Jarrett
J Shield
ZE Winters
JMP Holly
Publication date: 01-05-2008
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue Special Issue 2/2008
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr1923

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras

Prof. Fabrice Barlesi

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Special Issue 2/2008

De novo expression of αvβ6 integrin by myoepithelial cells in ductal carcinoma in situ may be an important marker of disease progression

Plasma MMP1, MMP8 and MMP13 expression in breast cancer: protective role of MMP8 against lymph node metastasis

Identification and definition of novel clinical phenotypes of breast cancer through consensus derived from automated clustering methods

The QUEST study: a multicentre randomised trial to assess the impact of the type and timing of breast reconstruction on quality of life following mastectomy

Investigation into the molecular mechanism of the antiapoptotic functions of CTCF in breast cancer cells using a proteomics approach

Breast cancer and environmental risk factors: an appraisal of the scientific evidence

Keynote webinar | Spotlight on antibody–drug conjugates in cancer