Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2000

01-12-2000 | Paper Report

Critical role of a stimulator/responder ratio between dendritic cells and CD4+ T cells for Th2 polarization

Author: Petya Dimitrova

Published in: Arthritis Research & Therapy | Issue 1/2000

Login to get access

Excerpt

Based on origin and nature of stimulation during maturation, dendritic cells (DCs) can differentiate into either DC type 1 (DC1) or DC type 2 (DC2) that induce Th1 or Th2 responses, respectively. It has previously been suggested that human monocyte-derived DCs develop into DC1, secrete high amounts of interleukin (IL)-12 in response to pathogens or pathogen-derived signals and thus promote Th1 differentiation. In this paper, the ability of human myeloid dendritic cells to induce polarized Th1 or Th2 cell differentiation was investigated. …
Literature
1.
Tanaka H, Demeure CE, Rubio M, Delespesse G, Sarfati M: Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors: role of stimulator/responder ratio. J Exp Med. 2000, 192: 405-411.CrossRef
Metadata
Title
Critical role of a stimulator/responder ratio between dendritic cells and CD4+ T cells for Th2 polarization
Author
Petya Dimitrova
Publication date
01-12-2000
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue 1/2000
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar-2000-66853

Other articles of this Issue 1/2000

Arthritis Research & Therapy 1/2000 Go to the issue

Paper Report

IL-12: a candidate autoimmunity susceptibility gene

Paper Report

Post-transcriptional regulation of TNF gene expression in vivo

Paper Report

Effect of anti-c5a on thymocyte apoptosis

Paper Report

VEGF production is induced by ligation of CD40

Paper Report

Correlation of sacroiliitis inflammatory change with MRI

Paper Report

IL-4 gene therapy for collagen arthritis
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Image Credits