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Published in: Multidisciplinary Respiratory Medicine 1/2010

Open Access 01-12-2010 | Original article

Effect of home-based pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis

Authors: Sevgi Ozalevli, Hayriye Kul Karaali, Duygu Ilgin, Eyup Sabri Ucan

Published in: Multidisciplinary Respiratory Medicine | Issue 1/2010

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Abstract

Objective

The aim of this study was to investigate the effects of a home-based pulmonary rehabilitation program on the functional outcome parameters in patients with idiopathic pulmonary fibrosis (IPF).

Design

A prospective study.

Patients

Seventeen patients diagnosed with IPF.

Methods

A home-based pulmonary rehabilitation program was carried out in 17 IPF patients for 12 weeks. Dyspnea severity during daily life activities (Medical Research Council Scale), pulmonary function (pulmonary function test), exercise capacity (6-minute walking test, 6MWD), and general health related quality of life (Medical Outcomes Short Form-36) were evaluated.

Results

A significant decrease in perceived dyspnea (p = 0.003) and leg fatigue (p < 0.05) severities, and an increase in the 6MWD (p = 0.04) and general health related quality of life scores (health perception, physical role, and emotional status subscores) were found after the program (p < 0.05).

Conclusion

Home-based pulmonary rehabilitation may reduce dyspnea and fatigue severities, and improve exercise capacity and health-related quality of life in patients with IPF. In the treatment of IPF patients, home-based pulmonary rehabilitation programs should be placed alongside the routine treatment options.
Literature
1.
go back to reference Katzenstein AL, Myers JL: Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am J Respir Crit Care Med. 1998, 157: 1301-1315.CrossRefPubMed Katzenstein AL, Myers JL: Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am J Respir Crit Care Med. 1998, 157: 1301-1315.CrossRefPubMed
2.
go back to reference American Thoracic Society: Idiopathic pulmonary fibrosis; diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med. 2000, 161: 646-664.CrossRef American Thoracic Society: Idiopathic pulmonary fibrosis; diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med. 2000, 161: 646-664.CrossRef
3.
go back to reference Widimsky J, Riedel M, Stanek V: Central haemodynamics during exercise in patients with restrictive pulmonary disease. Bull Eur Physiopathol Respir. 1977, 13: 369-379.PubMed Widimsky J, Riedel M, Stanek V: Central haemodynamics during exercise in patients with restrictive pulmonary disease. Bull Eur Physiopathol Respir. 1977, 13: 369-379.PubMed
4.
go back to reference Chang JA, Curtis JR, Patrick DL, Raghu G: Assessment of health-related quality of life in patients with interstitial lung disease. Chest. 1999, 116: 1175-1182. 10.1378/chest.116.5.1175.CrossRefPubMed Chang JA, Curtis JR, Patrick DL, Raghu G: Assessment of health-related quality of life in patients with interstitial lung disease. Chest. 1999, 116: 1175-1182. 10.1378/chest.116.5.1175.CrossRefPubMed
5.
go back to reference Jastrzebski D, Gumola A, Gawlik R, Kozielski J: Dyspnea and quality of life in patients with pulmonary fibrosis after six weeks of respiratory rehabilitation. J Physiol Pharmacol. 2006, 57 (Suppl 4): 139-148.PubMed Jastrzebski D, Gumola A, Gawlik R, Kozielski J: Dyspnea and quality of life in patients with pulmonary fibrosis after six weeks of respiratory rehabilitation. J Physiol Pharmacol. 2006, 57 (Suppl 4): 139-148.PubMed
6.
go back to reference Naji NA, Connor MC, Donnelly SC, McDonnell TJ: Effectiveness of pulmonary rehabilitation in restrictive lung disease. J Cardiopulm Rehabil. 2006, 26: 237-243. 10.1097/00008483-200607000-00007.CrossRefPubMed Naji NA, Connor MC, Donnelly SC, McDonnell TJ: Effectiveness of pulmonary rehabilitation in restrictive lung disease. J Cardiopulm Rehabil. 2006, 26: 237-243. 10.1097/00008483-200607000-00007.CrossRefPubMed
7.
go back to reference Ferreira A, Garvey C, Connors GL, Hilling L, Rigler J, Farrell S, Cayou C, Shariat C, Collard HR: Pulmonary rehabilitation in interstitial lung disease: benefits and predictors of response. Chest. 2009, 135: 442-447. 10.1378/chest.08-1458.CrossRefPubMed Ferreira A, Garvey C, Connors GL, Hilling L, Rigler J, Farrell S, Cayou C, Shariat C, Collard HR: Pulmonary rehabilitation in interstitial lung disease: benefits and predictors of response. Chest. 2009, 135: 442-447. 10.1378/chest.08-1458.CrossRefPubMed
8.
go back to reference Nishiyama O, Kondoh Y, Kimura T, Kato K, Kataoka K, Ogawa T, Watanabe F, Arizono S, Nishimura K, Taniguchi H: Effects of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis. Respirology. 2008, 13: 394-399. 10.1111/j.1440-1843.2007.01205.x.CrossRefPubMed Nishiyama O, Kondoh Y, Kimura T, Kato K, Kataoka K, Ogawa T, Watanabe F, Arizono S, Nishimura K, Taniguchi H: Effects of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis. Respirology. 2008, 13: 394-399. 10.1111/j.1440-1843.2007.01205.x.CrossRefPubMed
9.
go back to reference Holland AE, Hill CJ, Conron M, Munro P, McDonald CF: Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax. 2008, 63: 549-554. 10.1136/thx.2007.088070.CrossRefPubMed Holland AE, Hill CJ, Conron M, Munro P, McDonald CF: Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax. 2008, 63: 549-554. 10.1136/thx.2007.088070.CrossRefPubMed
10.
go back to reference Swigris JJ, Brown KK, Make BJ, Wamboldt FS: Pulmonary rehabilitation in idiopathic pulmonary fibrosis: a call for continued investigation. Respir Med. 2008, 102: 1675-1680. 10.1016/j.rmed.2008.08.014.PubMedCentralCrossRefPubMed Swigris JJ, Brown KK, Make BJ, Wamboldt FS: Pulmonary rehabilitation in idiopathic pulmonary fibrosis: a call for continued investigation. Respir Med. 2008, 102: 1675-1680. 10.1016/j.rmed.2008.08.014.PubMedCentralCrossRefPubMed
11.
go back to reference Ries AL, Kaplan RM, Myers R, Prewitt LM: Maintenance after pulmonary rehabilitation in chronic lung disease: a randomized trial. Am J Respir Crit Care Med. 2003, 167: 880-888. 10.1164/rccm.200204-318OC.CrossRefPubMed Ries AL, Kaplan RM, Myers R, Prewitt LM: Maintenance after pulmonary rehabilitation in chronic lung disease: a randomized trial. Am J Respir Crit Care Med. 2003, 167: 880-888. 10.1164/rccm.200204-318OC.CrossRefPubMed
12.
go back to reference Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S, Chronic Obstructive Pulmonary Disease Axis of Respiratory Health Network, Fonds de recherche en santé du Québec: Effects of homebased pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med. 2008, 16: 869-878.CrossRef Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S, Chronic Obstructive Pulmonary Disease Axis of Respiratory Health Network, Fonds de recherche en santé du Québec: Effects of homebased pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med. 2008, 16: 869-878.CrossRef
13.
go back to reference Wijkstra PJ, Strijbos JH, Koëter GH: Home-based rehabilitation for patients with COPD: organization, effects and financial implications. Monaldi Arch Chest Dis. 2000, 55: 130-134.PubMed Wijkstra PJ, Strijbos JH, Koëter GH: Home-based rehabilitation for patients with COPD: organization, effects and financial implications. Monaldi Arch Chest Dis. 2000, 55: 130-134.PubMed
14.
go back to reference Ong KC, Wong WP, Jailani AR, Sew S, Ong YY: Effects of a pulmonary rehabilitation programme on physiologic and psychosocial outcomes in patients with chronic respiratory disorders. Ann Acad Med Singapore. 2001, 30: 15-21.PubMed Ong KC, Wong WP, Jailani AR, Sew S, Ong YY: Effects of a pulmonary rehabilitation programme on physiologic and psychosocial outcomes in patients with chronic respiratory disorders. Ann Acad Med Singapore. 2001, 30: 15-21.PubMed
15.
go back to reference American Thoracic Society: Standardization of spirometry, 1994 Update. Am J Respir Crit Care Med. 1995, 152: 1107-1136. American Thoracic Society: Standardization of spirometry, 1994 Update. Am J Respir Crit Care Med. 1995, 152: 1107-1136.
16.
go back to reference Bestall JC, Paul EA, Garrod R, Garnham R, Jones PW, Wedzicha JA: Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999, 54: 581-586. 10.1136/thx.54.7.581.PubMedCentralCrossRefPubMed Bestall JC, Paul EA, Garrod R, Garnham R, Jones PW, Wedzicha JA: Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999, 54: 581-586. 10.1136/thx.54.7.581.PubMedCentralCrossRefPubMed
17.
go back to reference ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: Guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002, 116: 111-117. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: Guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002, 116: 111-117.
18.
go back to reference Mahler DA, Wells CK: Evaluation of clinical methods for rating dyspnea. Chest. 1988, 93: 580-586. 10.1378/chest.93.3.580.CrossRefPubMed Mahler DA, Wells CK: Evaluation of clinical methods for rating dyspnea. Chest. 1988, 93: 580-586. 10.1378/chest.93.3.580.CrossRefPubMed
19.
go back to reference Brazier JE, Harper R, Jones NM, O'Cathain A, Thomas KJ, Usherwood T, Westlake L: Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992, 305: 160-164. 10.1136/bmj.305.6846.160.PubMedCentralCrossRefPubMed Brazier JE, Harper R, Jones NM, O'Cathain A, Thomas KJ, Usherwood T, Westlake L: Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992, 305: 160-164. 10.1136/bmj.305.6846.160.PubMedCentralCrossRefPubMed
20.
go back to reference Demiral Y, Ergor G, Unal B, Akvardar Y, Kivircik B, Alptekin K: Normative data and discriminative properties of short form 36 (SF-36) in Turkish urban population. BMC Public Health. 2006, 6: 247-10.1186/1471-2458-6-247.PubMedCentralCrossRefPubMed Demiral Y, Ergor G, Unal B, Akvardar Y, Kivircik B, Alptekin K: Normative data and discriminative properties of short form 36 (SF-36) in Turkish urban population. BMC Public Health. 2006, 6: 247-10.1186/1471-2458-6-247.PubMedCentralCrossRefPubMed
21.
go back to reference Ware LB: Clinical Year in Review I: Interstitial Lung Disease, Pulmonary Vascular Disease, Pulmonary Infections, and Cardiopulmonary Exercise Testing and Pulmonary Rehabilitation. Proc Am Thorac Soc. 2009, 6: 487-493. 10.1513/pats.200907-057TT.CrossRefPubMed Ware LB: Clinical Year in Review I: Interstitial Lung Disease, Pulmonary Vascular Disease, Pulmonary Infections, and Cardiopulmonary Exercise Testing and Pulmonary Rehabilitation. Proc Am Thorac Soc. 2009, 6: 487-493. 10.1513/pats.200907-057TT.CrossRefPubMed
22.
go back to reference Spruit MA, Janssen DJ, Franssen FM, Wouters EF: Rehabilitation and palliative care in lung fibrosis. Respirology. 2009, 14: 781-787. 10.1111/j.1440-1843.2009.01599.x.CrossRefPubMed Spruit MA, Janssen DJ, Franssen FM, Wouters EF: Rehabilitation and palliative care in lung fibrosis. Respirology. 2009, 14: 781-787. 10.1111/j.1440-1843.2009.01599.x.CrossRefPubMed
23.
go back to reference Rusanov V, Shitrit D, Fox B, Amital A, Peled N, Kramer MR: Use of the 15-steps climbing exercise oximetry test in patients with idiopathic pulmonary fibrosis. Respir Med. 2008, 102: 1080-1088. 10.1016/j.rmed.2007.12.031.CrossRefPubMed Rusanov V, Shitrit D, Fox B, Amital A, Peled N, Kramer MR: Use of the 15-steps climbing exercise oximetry test in patients with idiopathic pulmonary fibrosis. Respir Med. 2008, 102: 1080-1088. 10.1016/j.rmed.2007.12.031.CrossRefPubMed
24.
go back to reference Perez RL: Interstitial lung disease: causes, treatment, and prevention. Ethn Dis. 2005, 15 (2 Suppl 2): S45-48.PubMed Perez RL: Interstitial lung disease: causes, treatment, and prevention. Ethn Dis. 2005, 15 (2 Suppl 2): S45-48.PubMed
25.
go back to reference Ries AL: The importance of exercise in pulmonary rehabilitation. Clin Chest Med. 1994, 15: 327-337.PubMed Ries AL: The importance of exercise in pulmonary rehabilitation. Clin Chest Med. 1994, 15: 327-337.PubMed
Metadata
Title
Effect of home-based pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis
Authors
Sevgi Ozalevli
Hayriye Kul Karaali
Duygu Ilgin
Eyup Sabri Ucan
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Multidisciplinary Respiratory Medicine / Issue 1/2010
Electronic ISSN: 2049-6958
DOI
https://doi.org/10.1186/2049-6958-5-1-31

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