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Journal of Ophthalmic Inflammation and Infection

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Open Access 01-12-2013 | Review

Sarcoidosis in tuberculosis-endemic regions: India

Author: Kalpana Babu

Published in: Journal of Ophthalmic Inflammation and Infection | Issue 1/2013

Abstract

Sarcoidosis is a multisystem inflammatory disease of unknown etiology affecting multiple organs. Earlier reports suggested that sarcoidosis was a disease of the developed world. However, recent reports suggest that the disease is found in the developing countries as well. Clinical, radiological, and histopathological similarities with tuberculosis pose a great challenge in countries endemic for tuberculosis. Mantoux test, high resolution computed tomography, and transbronchial lymph node and lung biopsies are diagnostic modalities, which play an important role in the diagnosis of sarcoid. In this review, we look at the epidemiology of sarcoid in tuberculosis-endemic regions, the sarcoidosis-tuberculosis link, clinical profile, diagnostic modalities, dilemma in the diagnosis, and the treatment of this disease.

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Newman LS, Rose CS, Maier LA: Sarcoidosis. N Engl J Med 1997, 336: 1223–1234. 10.1056/NEJM199704243361705CrossRef

Hosoda Y, Kosuda T, Yamamoto M, Hongo O, Mochizumi H, Mikami R, Homma H, Fujita S, Ohira I, Izumi T, Kobara Y, Yammato H, Oshima S, Teramatsu T, Maekawa N, Tsuji S, Soon CP, Sodhy TS, Bovornkitti S, Chakravarty SC, Yang SP, Gomaa T: A cooperative study of sarcoidosis in Asia and Africa: descriptive epidemiology. Ann N Y Acad Sci 1976, 278: 347–354. 10.1111/j.1749-6632.1976.tb47045.xPubMedCrossRef

Jindal SK, Gupta D, Aggarwal AN: Sarcoidosis in developing countries. Curr Opin Pulm Med 2000,6(5):448–454. 10.1097/00063198-200009000-00011PubMedCrossRef

Gupta D, Agarwal R, Aggarwal AN, Jindal SK: Sarcoidosis and tuberculosis: the same disease with different manifestations or similar manifestations of different disorders. Curr Opin Pulm Med 2012,18(5):506–516. 10.1097/MCP.0b013e3283560809PubMedCrossRef

Gupta D, Agarwal R, Aggarwal N, Jindal SK: Molecular evidence for the role of mycobacteria in sarcoidosis: a meta analysis. Eur Respir J 2007, 30: 508–516. 10.1183/09031936.00002607PubMedCrossRef

Gupta D, Kumar S, Aggarwal AN, Verma I, Agarwal R: Interferon gamma release assay (QuantiFERON-TB Gold In Tube) in patients of sarcoidosis from a population with high prevalence of tuberculosis infection. Sarcoidosis Vasc Diffuse Lung Dis 2011,28(2):95–101.PubMed

Kumar R, Goel N, Gaur SN: Sarcoidosis in north Indian population: a retrospective study. Indian J Chest Dis Allied Sci 2012,54(2):99–104.PubMed

Babu K, Kini R, Mehta R, Philips M, Subbakrishna DK, Murthy KR: Predictors for tubercular uveitis: a comparison between biopsy-proven cases of tubercular and sarcoid uveitis. Retina 2012,32(5):1017–1020. 10.1097/IAE.0b013e31822d3a20PubMedCrossRef

Babu K, Kini R, Mehta R, Abraham MP, Subbakrishna DK, Murthy KR: Clinical profile of ocular sarcoidosis in a South Indian patient population. Ocul Immunol Inflamm 2010,18(5):362–369. 10.3109/09273948.2010.495813PubMedCrossRef

10.

Khanna A, Sidhu U, Bajwa G, Malhotra V: Pattern of ocular manifestations in patients with sarcoidosis in developing countries. Acta Ophthalmol Scand 2007,85(6):609–612. 10.1111/j.1600-0420.2006.00791.xPubMedCrossRef

11.

Mootha VK, Agarwal R, Aggarwal AN, Gupta D, Ahmed J, Verma I, Bal A: The sarcoid-tuberculosis link: evidence from a high TB prevalence country. J Infect 2010,60(6):501–503. 10.1016/j.jinf.2010.03.010PubMedCrossRef

12.

Agarwal R, Aggarwal AN, Gupta D: Efficacy and safety of conventional TBNA in sarcoidosis: a systematic review and meta-analysis. Respir Care 2012. in press

13.

Sharma SK, Mohan A: Sarcoidosis in India: not so rare. J Indian Acad Clin Med 2004,5(1):12–21.

14.

Anantham D, Ong SJ, Chuah KL, Fook-Chong S, Hsu A, Eng P: Sarcoidosis in Singapore: epidemiology, clinical presentation and ethnic differences. Respirology 2007,12(3):355–360. 10.1111/j.1440-1843.2007.01074.xPubMedCrossRef

15.

Liam CK, Menon A: Sarcoidosis: a review of cases seen at the university hospital, Kuala Lumpur. Singapore Med J 1993,34(2):153–156.PubMed

16.

Pathanapitoon K, Goossens JH, van Tilborg TC, Kunavisarut P, Choovuthayakorn J, Rothova A: Ocular sarcoidosis in Thailand. Eye (Lond) 2010,24(11):1669–1674. 10.1038/eye.2010.107CrossRef

17.

Sheu SJ, Chang FP, Wu TT, Chuang CT: Ocular sarcoidosis in southern Taiwan. Ocul Immunol Inflamm 2010,18(3):152–157. 10.3109/09273941003637502PubMedCrossRef

18.

Babu K, Kini R, Mehta R: Scleral nodule and bilateral disc edema as a presenting manifestation of systemic sarcoidosis. Ocul Immunol Inflamm 2010,18(3):158–161. 10.3109/09273941003753416PubMedCrossRef

19.

Biswas J, Krishnakumar S, Raghavendran R, Mahesh L: Lid swelling and diplopia as presenting features of orbital sarcoid. Indian J Ophthalmol 2000,48(3):231–233.PubMed

20.

Shabbir Shafiq J, Biswas J: Optic nerve head sarcoid granuloma treated with intravenous methyl prednisolone. Oman J Ophthalmol 2008,1(1):28–31. 10.4103/0974-620X.43318CrossRef

21.

Verma A, Biswas J: Choroidal granuloma as an initial manifestation of systemic sarcoidosis. Int Ophthalmol 2010,30(5):603–606. 10.1007/s10792-009-9328-5PubMedCrossRef

22.

Ganesh SK, Roopleen BJ, Veena N: Role of high-resolution computerized tomography (HRCT) of the chest in granulomatous uveitis: a tertiary uveitis clinic experience from India. Ocul Immunol Inflamm 2011,19(1):51–57. 10.3109/09273948.2010.525680PubMedCrossRef

23.

Brownell I, Ramirez-Valle F, Sanchez M, Prystowsky S: Evidence for mycobacteria in sarcoidosis. Am J Respir Cell Mol Biol 2011, 45: 899–905. 10.1165/rcmb.2010-0433TRPubMedCentralPubMedCrossRef

24.

Scadding JG: Mycobacterium tuberculosis in the aetiology of sarcoidosis. Br Med J 1960, 2: 1617–1623. 10.1136/bmj.2.5213.1617PubMedCentralPubMedCrossRef

25.

Drake WP, Newman LS: Mycobacterial antigens may be important in sarcoidosis pathogenesis. Curr Opin Pulm Med 2006, 12: 359–363. 10.1097/01.mcp.0000239554.01068.94PubMedCrossRef

26.

Parsons V: Awareness of family and contact history of tuberculosis in generalized sarcoidosis. Br Med J 1960, 2: 1756–1759. 10.1136/bmj.2.5215.1756PubMedCentralPubMedCrossRef

27.

Hosoda Y, Sasagawa S, Yamaguchi T: Sarcoidosis and tuberculosis: epidemiological similarities and dissimilarities. A review of a series of studies in a Japanese work population (1941–1996) and the general population (1959–1984). Sarcoidosis Vasc Diffuse Lung Dis 2004,21(2):85–93.PubMed

28.

Hosoda Y, Yamaguchi M, Hiraga Y: Global epidemiology of sarcoidosis. What story do prevalence and incidence tell us? Clin Chest Med 1997,18(4):681–694. 10.1016/S0272-5231(05)70412-3PubMedCrossRef

29.

Drake WP, Newman LS: Mycobacterial antigens may be important in sarcoidosis pathogenesis. Curr Opin Pulm Med 2006,12(5):359–363. 10.1097/01.mcp.0000239554.01068.94PubMedCrossRef

30.

Agarwal R, Gupta D, Srinivas R, Verma I, Aggarwal AN, Laal S: Analysis of humoral responses to proteins encoded by region of difference 1 of mycobacterium tuberculosis in sarcoidosis in a high tuberculosis prevalence country. Indian J Med Res 2012,135(6):920–923.PubMedCentralPubMed

31.

Chan AS, Sharma OP, Rao NA: Review for disease of the year: immunopathogenesis of ocular sarcoidosis. Ocul Immunol Inflamm 2010,18(3):143–151. 10.3109/09273948.2010.481772PubMedCrossRef

32.

Song Z, Marzilli L, Greenlee BM, Chen ES, Silver RF, Askin FB, Teirstein AS, Zhang Y, Cotter RJ, Moller DR: Mycobacterial catalase-peroxidase is a tissue antigen and target of the adaptive immune response in systemic sarcoidosis. J Exp Med 2005,201(5):755–767. Erratum in: J Exp Med. 2005; 202(5):721 10.1084/jem.20040429PubMedCentralPubMedCrossRef

33.

Chen ES, Wahlström J, Song Z, Willett MH, Wikén M, Yung RC, West EE, McDyer JF, Zhang Y, Eklund A, Grunewald J, Moller DR: T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis. J Immunol 2008,181(12):8784–8796.PubMedCentralPubMedCrossRef

34.

Kim UR, Khazaei H, Stewart WB, Shah AD: Spectrum of orbital disease in South India: an Aravind study of 6328 consecutive patients. Ophthal Plast Reconst Surg 2010,26(5):315–322. 10.1097/IOP.0b013e3181c32f2fCrossRef

35.

Rothova A: Ocular involvement in sarcoidosis. Br J Ophthalmol 2000,84(1):110–116. 10.1136/bjo.84.1.110PubMedCentralPubMedCrossRef

36.

Smith-Rohrberg D, Sharma SK: Tuberculin skin test among pulmonary sarcoidosis patients with and without tuberculosis: its utility for the screening of the two conditions in tuberculosis-endemic regions. Sarcoidosis Vasc Diffuse Lung Dis 2006,23(2):130–134.PubMed

37.

Bansal R, Gupta A, Gupta V, Dogra MR, Sharma A, Bambery P: Tubercular serpiginous-like choroiditis presenting as multifocal serpiginoid choroiditis. Ophthalmology 2012,119(11):2334–2342. 10.1016/j.ophtha.2012.05.034PubMedCrossRef

38.

Bansal RK, Malhotra C, Bhatia R, Chhabra S, Sood S: Tubercular dacryoadenitis–a case report and review of literature. Indian J Pathol Microbiol 2006,49(3):385–387.PubMed

39.

Baughman RP, Lower EE, Ingledue R, Kaufman AH: Management of ocular sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 2012,29(1):26–33.PubMed

40.

Bhat P, Cervantes-Castañeda RA, Doctor PP, Anzaar F, Foster CS: Mycophenolate mofetil therapy for sarcoidosis-associated uveitis. Ocul Immunol Inflamm 2009,17(3):185–190. 10.1080/09273940902862992PubMedCrossRef

41.

Lower EE, Baughman RP, Kaufman AH: Rituximab for refractory granulomatous eye disease. Clin Ophthalmol 2012, 6: 1613–1618.PubMedCentralPubMed

Title: Sarcoidosis in tuberculosis-endemic regions: India
Author: Kalpana Babu
Publication date: 01-12-2013
Publisher: Springer Berlin Heidelberg
Published in: Journal of Ophthalmic Inflammation and Infection / Issue 1/2013
Electronic ISSN: 1869-5760
DOI: https://doi.org/10.1186/1869-5760-3-53

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Sarcoidosis in tuberculosis-endemic regions: India

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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