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Open Access 01-12-2012 | Short report

Omentin as a novel biomarker of metabolic risk factors

Authors: Rei Shibata, Noriyuki Ouchi, Ryotaro Takahashi, Yuya Terakura, Koji Ohashi, Nobuo Ikeda, Akiko Higuchi, Hiroko Terasaki, Shinji Kihara, Toyoaki Murohara

Published in: Diabetology & Metabolic Syndrome | Issue 1/2012

Abstract

Background

Omentin is an adipocytokine that is abundantly expressed in visceral fat tissue. We investigated the association of omentin with the number of metabolic risk factors.

Finding

The study population comprised 201 Japanese men who underwent annual health checkups. Plasma omentin levels were determined by enzyme-linked immunosorbent assay. We divided the subjects into 4 groups according to omentin levels. A reduction of plasma omentin levels significantly correlated with an increase in the mean number of metabolic risk factors such as increased waist circumference, dyslipidemia, high blood pressure and glucose intolerance.

Conclusions

Circulating omentin levels negatively correlated with the multiplicity of metabolic risk factors, suggesting that omentin acts as a biomarker of metabolic disorders.

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Title: Omentin as a novel biomarker of metabolic risk factors
Authors: Rei Shibata
Noriyuki Ouchi
Ryotaro Takahashi
Yuya Terakura
Koji Ohashi
Nobuo Ikeda
Akiko Higuchi
Hiroko Terasaki
Shinji Kihara
Toyoaki Murohara
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Diabetology & Metabolic Syndrome / Issue 1/2012
Electronic ISSN: 1758-5996
DOI: https://doi.org/10.1186/1758-5996-4-37

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