Skip to main content
Top
Published in: Journal of the International AIDS Society 1/2011

Open Access 01-12-2011 | Research

Sexual risk taking among patients on antiretroviral therapy in an urban informal settlement in Kenya: a cross-sectional survey

Authors: Anders Ragnarsson, Anna Mia Ekström, Jane Carter, Festus Ilako, Abigail Lukhwaro, Gaetano Marrone, Anna Thorson

Published in: Journal of the International AIDS Society | Issue 1/2011

Login to get access

Abstract

Background

Our intention was to analyze demographic and contextual factors associated with sexual risk taking among HIV-infected patients on antiretroviral treatment (ART) in Africa's largest informal urban settlement, Kibera in Nairobi, Kenya.

Methods

We used a cross-sectional survey in a resource-poor, urban informal settlement in Nairobi; 515 consecutive adult patients on ART attending the African Medical and Research Foundation clinic in Kibera in Nairobi were included in the study. Interviewers used structured questionnaires covering socio-demographic characteristics, time on ART, number of sexual partners during the previous six months and consistency of condom use.

Results

Twenty-eight percent of patients reported inconsistent condom use. Female patients were significantly more likely than men to report inconsistent condom use (aOR 3.03; 95% CI 1.60-5.72). Shorter time on ART was significantly associated with inconsistent condom use. Multiple sexual partners were more common among married men than among married women (adjusted OR 4.38; 95% CI 1.82-10.51).

Conclusions

Inconsistent condom use was especially common among women and patients who had recently started ART, i.e., when the risk of HIV transmission is higher. Having multiple partners was quite common, especially among married men, with the potential of creating sexual networks and an increased risk of HIV transmission. ART needs to be accompanied by other preventive interventions to reduce the risk of new HIV infections among sero-discordant couples and to increase overall community effectiveness.
Literature
2.
go back to reference Moatti JP, Spire B: HIV/AIDS: a long-term research agenda for social sciences. AIDS Care 2008,20(4):407–12.PubMedCrossRef Moatti JP, Spire B: HIV/AIDS: a long-term research agenda for social sciences. AIDS Care 2008,20(4):407–12.PubMedCrossRef
3.
go back to reference Cambiano V, Rodger AJ, Phillips AN: 'Test-and-treat': the end of the HIV epidemic? Curr Opin Infect Dis 2011,24(1):19–26.PubMedCrossRef Cambiano V, Rodger AJ, Phillips AN: 'Test-and-treat': the end of the HIV epidemic? Curr Opin Infect Dis 2011,24(1):19–26.PubMedCrossRef
4.
go back to reference Abbas UL, Anderson RM, Mellors JW: Potential impact of antiretroviral therapy on HIV-1 transmission and AIDS mortality in resource-limited settings. J Acquir Immune Defic Syndr 2006,41(5):632–41.PubMedCrossRef Abbas UL, Anderson RM, Mellors JW: Potential impact of antiretroviral therapy on HIV-1 transmission and AIDS mortality in resource-limited settings. J Acquir Immune Defic Syndr 2006,41(5):632–41.PubMedCrossRef
5.
go back to reference Gray RH, Li X, Wawer MJ, Gange SJ, Serwadda D, Sewankambo NK, Moore R, Wabwire-Mangen F, Lutalo T, Quinn TC: Stochastic simulation of the impact of antiretroviral therapy and HIV vaccines on HIV transmission; Rakai, Uganda. Aids 2003,17(13):1941–51.PubMedCrossRef Gray RH, Li X, Wawer MJ, Gange SJ, Serwadda D, Sewankambo NK, Moore R, Wabwire-Mangen F, Lutalo T, Quinn TC: Stochastic simulation of the impact of antiretroviral therapy and HIV vaccines on HIV transmission; Rakai, Uganda. Aids 2003,17(13):1941–51.PubMedCrossRef
6.
go back to reference Adimora AA, Schoenbach VJ: Social context, sexual networks, and racial disparities in rates of sexually transmitted infections. J Infect Dis 2005,191(Suppl 1):S115–22.PubMedCrossRef Adimora AA, Schoenbach VJ: Social context, sexual networks, and racial disparities in rates of sexually transmitted infections. J Infect Dis 2005,191(Suppl 1):S115–22.PubMedCrossRef
7.
8.
go back to reference Shelton JD, Halperin DT, Nantulya V, Potts M, Gayle HD, Holmes KK: Partner reduction is crucial for balanced "ABC" approach to HIV prevention. Bmj 2004,328(7444):891–3.PubMedCrossRef Shelton JD, Halperin DT, Nantulya V, Potts M, Gayle HD, Holmes KK: Partner reduction is crucial for balanced "ABC" approach to HIV prevention. Bmj 2004,328(7444):891–3.PubMedCrossRef
9.
go back to reference Unge C, Sodergard B, Ekstrom AM, Carter J, Waweru M, Ilako F, Ragnarsson A, Thorson A: Challenges for scaling up ART in a resource-limited setting: a retrospective study in Kibera, Kenya. J Acquir Immune Defic Syndr 2009,50(4):397–402.PubMedCrossRef Unge C, Sodergard B, Ekstrom AM, Carter J, Waweru M, Ilako F, Ragnarsson A, Thorson A: Challenges for scaling up ART in a resource-limited setting: a retrospective study in Kibera, Kenya. J Acquir Immune Defic Syndr 2009,50(4):397–402.PubMedCrossRef
10.
go back to reference Garnett GP, Johnson AM: Coining a new term in epidemiology: concurrency and HIV. Aids 1997,11(5):681–3.PubMedCrossRef Garnett GP, Johnson AM: Coining a new term in epidemiology: concurrency and HIV. Aids 1997,11(5):681–3.PubMedCrossRef
11.
go back to reference Drumright LN, Gorbach PM, Holmes KK: Do people really know their sex partners? Concurrency, knowledge of partner behavior, and sexually transmitted infections within partnerships. Sex Transm Dis 2004,31(7):437–42.PubMedCrossRef Drumright LN, Gorbach PM, Holmes KK: Do people really know their sex partners? Concurrency, knowledge of partner behavior, and sexually transmitted infections within partnerships. Sex Transm Dis 2004,31(7):437–42.PubMedCrossRef
12.
go back to reference Caplan P, ed: The cultural construction of sexuality. Routlege: New York; 1987:10. Caplan P, ed: The cultural construction of sexuality. Routlege: New York; 1987:10.
13.
14.
go back to reference Halperin DT, Epstein H: Concurrent sexual partnerships help to explain Africa's high HIV prevalence: implications for prevention. Lancet 2004,364(9428):4–6.PubMedCrossRef Halperin DT, Epstein H: Concurrent sexual partnerships help to explain Africa's high HIV prevalence: implications for prevention. Lancet 2004,364(9428):4–6.PubMedCrossRef
15.
go back to reference Quinn TC, Wawer MJ, Sewankambo N, Serwadda D, Li C, Wabwire-Mangen F, Meehan MO, Lutalo T, Gray RH: Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Grou. N Engl J Med 2000,342(13):921–9.PubMedCrossRef Quinn TC, Wawer MJ, Sewankambo N, Serwadda D, Li C, Wabwire-Mangen F, Meehan MO, Lutalo T, Gray RH: Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Grou. N Engl J Med 2000,342(13):921–9.PubMedCrossRef
16.
go back to reference Boily MC, Godin G, Hogben M, Sherr L, Bastos FI: The impact of the transmission dynamics of the HIV/AIDS epidemic on sexual behaviour: a new hypothesis to explain recent increases in risk taking-behaviour among men who have sex with men. Med Hypotheses 2005,65(2):215–26.PubMedCrossRef Boily MC, Godin G, Hogben M, Sherr L, Bastos FI: The impact of the transmission dynamics of the HIV/AIDS epidemic on sexual behaviour: a new hypothesis to explain recent increases in risk taking-behaviour among men who have sex with men. Med Hypotheses 2005,65(2):215–26.PubMedCrossRef
17.
go back to reference Elford J: Changing patterns of sexual behaviour in the era of highly active antiretroviral therapy. Curr Opin Infect Dis 2006,19(1):26–32.PubMedCrossRef Elford J: Changing patterns of sexual behaviour in the era of highly active antiretroviral therapy. Curr Opin Infect Dis 2006,19(1):26–32.PubMedCrossRef
18.
go back to reference Stolte IG, de Wit JB, van Eeden A, Coutinho RA, Dukers NH: Perceived viral load, but not actual HIV-1-RNA load, is associated with sexual risk behaviour among HIV-infected homosexual men. Aids 2004,18(14):1943–9.PubMedCrossRef Stolte IG, de Wit JB, van Eeden A, Coutinho RA, Dukers NH: Perceived viral load, but not actual HIV-1-RNA load, is associated with sexual risk behaviour among HIV-infected homosexual men. Aids 2004,18(14):1943–9.PubMedCrossRef
19.
go back to reference Vanable PA, Ostrow DG, McKirnan DJ: Viral load and HIV treatment attitudes as correlates of sexual risk behavior among HIV-positive gay men. J Psychosom Res 2003,54(3):263–9.PubMedCrossRef Vanable PA, Ostrow DG, McKirnan DJ: Viral load and HIV treatment attitudes as correlates of sexual risk behavior among HIV-positive gay men. J Psychosom Res 2003,54(3):263–9.PubMedCrossRef
20.
go back to reference Blackard JT, Mayer KH: HIV superinfection in the era of increased sexual risk-taking. Sex Transm Dis 2004,31(4):201–4.PubMedCrossRef Blackard JT, Mayer KH: HIV superinfection in the era of increased sexual risk-taking. Sex Transm Dis 2004,31(4):201–4.PubMedCrossRef
21.
go back to reference Kozal MJ, Amico KR, Chiarella J, Schreibman T, Cornman D, Fisher W, Fisher J, Friedland G: Antiretroviral resistance and high-risk transmission behavior among HIV-positive patients in clinical care. Aids 2004,18(16):2185–9.PubMedCrossRef Kozal MJ, Amico KR, Chiarella J, Schreibman T, Cornman D, Fisher W, Fisher J, Friedland G: Antiretroviral resistance and high-risk transmission behavior among HIV-positive patients in clinical care. Aids 2004,18(16):2185–9.PubMedCrossRef
22.
go back to reference Crepaz N, Hart TA, Marks G: Highly active antiretroviral therapy and sexual risk behavior: a meta-analytic review. Jama 2004,292(2):224–36.PubMedCrossRef Crepaz N, Hart TA, Marks G: Highly active antiretroviral therapy and sexual risk behavior: a meta-analytic review. Jama 2004,292(2):224–36.PubMedCrossRef
23.
go back to reference Kennedy C, O'Reilly K, Medley A, Sweat M: The impact of HIV treatment on risk behaviour in developing countries: a systematic review. AIDS Care 2007,19(6):707–20.PubMedCrossRef Kennedy C, O'Reilly K, Medley A, Sweat M: The impact of HIV treatment on risk behaviour in developing countries: a systematic review. AIDS Care 2007,19(6):707–20.PubMedCrossRef
24.
go back to reference Van Damme W, Kober K, Kegels G: Scaling-up antiretroviral treatment in Southern African countries with human resource shortage: how will health systems adapt? Soc Sci Med 2008,66(10):2108–21.PubMedCrossRef Van Damme W, Kober K, Kegels G: Scaling-up antiretroviral treatment in Southern African countries with human resource shortage: how will health systems adapt? Soc Sci Med 2008,66(10):2108–21.PubMedCrossRef
25.
go back to reference Van Damme W, Kober K, Laga M: The real challenges for scaling up ART in sub-Saharan Africa. Aids 2006,20(5):653–6.PubMedCrossRef Van Damme W, Kober K, Laga M: The real challenges for scaling up ART in sub-Saharan Africa. Aids 2006,20(5):653–6.PubMedCrossRef
26.
go back to reference Ragnarsson A, Thorson A, Dover P, Carter J, Ilako F, Indalo D, Ekstrom AM: Sexual risk-reduction strategies among HIV-infected men receiving ART in Kibera, Nairobi. AIDS Care 2011,23(3):315–21.PubMedCrossRef Ragnarsson A, Thorson A, Dover P, Carter J, Ilako F, Indalo D, Ekstrom AM: Sexual risk-reduction strategies among HIV-infected men receiving ART in Kibera, Nairobi. AIDS Care 2011,23(3):315–21.PubMedCrossRef
27.
go back to reference Sarna A, Chersich M, Okal J, Luchters SM, Mandaliya KN, Rutenberg N, Temmerman M: Changes in sexual risk taking with antiretroviral treatment: influence of context and gender norms in Mombasa, Kenya. Cult Health Sex 2009,11(8):783–97.PubMedCrossRef Sarna A, Chersich M, Okal J, Luchters SM, Mandaliya KN, Rutenberg N, Temmerman M: Changes in sexual risk taking with antiretroviral treatment: influence of context and gender norms in Mombasa, Kenya. Cult Health Sex 2009,11(8):783–97.PubMedCrossRef
28.
go back to reference Wilson DP, Law MG, Grulich AE, Cooper DA, Kaldor JM: Relation between HIV viral load and infectiousness: a model-based analysis. Lancet 2008,372(9635):314–20.PubMedCrossRef Wilson DP, Law MG, Grulich AE, Cooper DA, Kaldor JM: Relation between HIV viral load and infectiousness: a model-based analysis. Lancet 2008,372(9635):314–20.PubMedCrossRef
29.
go back to reference Eisele TP, Mathews C, Chopra M, Lurie MN, Brown L, Dewing S, Kendall C: Changes in risk behavior among HIV-positive patients during their first year of antiretroviral therapy in Cape Town South Africa. AIDS Behav 2009,13(6):1097–105.PubMedCrossRef Eisele TP, Mathews C, Chopra M, Lurie MN, Brown L, Dewing S, Kendall C: Changes in risk behavior among HIV-positive patients during their first year of antiretroviral therapy in Cape Town South Africa. AIDS Behav 2009,13(6):1097–105.PubMedCrossRef
30.
go back to reference UNAIDS: AIDS epidemic update: November 2009. UNAIDS: Geneva; 2009. UNAIDS: AIDS epidemic update: November 2009. UNAIDS: Geneva; 2009.
31.
go back to reference AMREF: Personal communication. Nairobi. 2008. AMREF: Personal communication. Nairobi. 2008.
32.
go back to reference Eisele TP, Mathews C, Chopra M, Brown L, Silvestre E, Daries V, Kendall C: High levels of risk behavior among people living with HIV Initiating and waiting to start antiretroviral therapy in Cape Town South Africa. AIDS Behav 2008,12(4):570–7.PubMedCrossRef Eisele TP, Mathews C, Chopra M, Brown L, Silvestre E, Daries V, Kendall C: High levels of risk behavior among people living with HIV Initiating and waiting to start antiretroviral therapy in Cape Town South Africa. AIDS Behav 2008,12(4):570–7.PubMedCrossRef
33.
go back to reference Unge C, Johansson A, Zachariah R, Some D, Van Engelgem I, Ekstrom AM: Reasons for unsatisfactory acceptance of antiretroviral treatment in the urban Kibera slum, Kenya. AIDS Care 2008,20(2):146–9.PubMedCrossRef Unge C, Johansson A, Zachariah R, Some D, Van Engelgem I, Ekstrom AM: Reasons for unsatisfactory acceptance of antiretroviral treatment in the urban Kibera slum, Kenya. AIDS Care 2008,20(2):146–9.PubMedCrossRef
34.
go back to reference Unge C, Sodergard B, Marrone G, Thorson A, Lukhwaro A, Carter J, Ilako F, Ekstrom AM: Long-term adherence to antiretroviral treatment and program drop-out in a high-risk urban setting in sub-saharan Africa: a prospective cohort study. PLoS One 2010,5(10):e13613.PubMedCrossRef Unge C, Sodergard B, Marrone G, Thorson A, Lukhwaro A, Carter J, Ilako F, Ekstrom AM: Long-term adherence to antiretroviral treatment and program drop-out in a high-risk urban setting in sub-saharan Africa: a prospective cohort study. PLoS One 2010,5(10):e13613.PubMedCrossRef
35.
go back to reference Zulu EM, Dodoo FN, Chika-Ezee A: Sexual risk-taking in the slums of Nairobi, Kenya, 1993–8. Popul Stud (Camb) 2002,56(3):311–23.CrossRef Zulu EM, Dodoo FN, Chika-Ezee A: Sexual risk-taking in the slums of Nairobi, Kenya, 1993–8. Popul Stud (Camb) 2002,56(3):311–23.CrossRef
36.
go back to reference Kretzschmar M, Morris M: Measures of concurrency in networks and the spread of infectious disease. Math Biosci 1996,133(2):165–95.PubMedCrossRef Kretzschmar M, Morris M: Measures of concurrency in networks and the spread of infectious disease. Math Biosci 1996,133(2):165–95.PubMedCrossRef
37.
go back to reference Delaney RO, Bautista DT, Serovich JM: Pregnancy decisions among women with HIV. AIDS Behav 2007,11(6):927–35.PubMedCrossRef Delaney RO, Bautista DT, Serovich JM: Pregnancy decisions among women with HIV. AIDS Behav 2007,11(6):927–35.PubMedCrossRef
38.
go back to reference Gruskin S, Firestone R, Maccarthy S, Ferguson L: HIV and pregnancy intentions: do services adequately respond to women's needs? Am J Public Health 2008,98(10):1746–50.PubMedCrossRef Gruskin S, Firestone R, Maccarthy S, Ferguson L: HIV and pregnancy intentions: do services adequately respond to women's needs? Am J Public Health 2008,98(10):1746–50.PubMedCrossRef
39.
go back to reference Hirsch JS: Gender, sexuality, and antiretroviral therapy: using social science to enhance outcomes and inform secondary prevention strategies. Aids 2007,21(Suppl 5):S21–9.PubMedCrossRef Hirsch JS: Gender, sexuality, and antiretroviral therapy: using social science to enhance outcomes and inform secondary prevention strategies. Aids 2007,21(Suppl 5):S21–9.PubMedCrossRef
40.
go back to reference McCarraher D, Cuthbertson C, Kung'u D, Otterness C, Johnson L, Magiri G: Sexual behavior, fertility desires and unmet need for family planning among home-based care clients and caregivers in Kenya. AIDS Care 2008,20(9):1057–65.PubMedCrossRef McCarraher D, Cuthbertson C, Kung'u D, Otterness C, Johnson L, Magiri G: Sexual behavior, fertility desires and unmet need for family planning among home-based care clients and caregivers in Kenya. AIDS Care 2008,20(9):1057–65.PubMedCrossRef
41.
go back to reference Smith DJ, Mbakwem BC: Life projects and therapeutic itineraries: marriage, fertility, and antiretroviral therapy in Nigeria. Aids 2007,21(Suppl 5):S37–41.PubMedCrossRef Smith DJ, Mbakwem BC: Life projects and therapeutic itineraries: marriage, fertility, and antiretroviral therapy in Nigeria. Aids 2007,21(Suppl 5):S37–41.PubMedCrossRef
42.
go back to reference Wagner GJ, Holloway I, Ghosh-Dastidar B, Ryan G, Kityo C, Mugyenyi C: Factors associated with condom use among HIV clients in stable relationships with partners at varying risk for HIV in Uganda. AIDS Behav 2010,14(5):1055–65.PubMedCrossRef Wagner GJ, Holloway I, Ghosh-Dastidar B, Ryan G, Kityo C, Mugyenyi C: Factors associated with condom use among HIV clients in stable relationships with partners at varying risk for HIV in Uganda. AIDS Behav 2010,14(5):1055–65.PubMedCrossRef
43.
go back to reference Courtenay WH: Constructions of masculinity and their influence on men's well-being: a theory of gender and health. Soc Sci Med 2000,50(10):1385–401.PubMedCrossRef Courtenay WH: Constructions of masculinity and their influence on men's well-being: a theory of gender and health. Soc Sci Med 2000,50(10):1385–401.PubMedCrossRef
44.
go back to reference Ragnarsson A, Townsend L, Thorson A, Chopra M, Ekstrom AM: Social networks and concurrent sexual relationships--a qualitative study among men in an urban South African community. AIDS Care 2009,21(10):1253–8.PubMedCrossRef Ragnarsson A, Townsend L, Thorson A, Chopra M, Ekstrom AM: Social networks and concurrent sexual relationships--a qualitative study among men in an urban South African community. AIDS Care 2009,21(10):1253–8.PubMedCrossRef
45.
go back to reference Eisele TP, Mathews C, Chopra M, Lurie MN, Brown L, Dewing S, Kendall C: Changes in Risk Behavior Among HIV-Positive Patients During Their First Year of Antiretroviral Therapy in Cape Town South Africa. AIDS Behav 2008. Eisele TP, Mathews C, Chopra M, Lurie MN, Brown L, Dewing S, Kendall C: Changes in Risk Behavior Among HIV-Positive Patients During Their First Year of Antiretroviral Therapy in Cape Town South Africa. AIDS Behav 2008.
46.
go back to reference Bunnell R, Ekwaru JP, Solberg P, Wamai N, Bikaako-Kajura W, Were W, Coutinho A, Liechty C, Madraa E, Rutherford G, Mermin J: Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural Uganda. Aids 2006,20(1):85–92.PubMedCrossRef Bunnell R, Ekwaru JP, Solberg P, Wamai N, Bikaako-Kajura W, Were W, Coutinho A, Liechty C, Madraa E, Rutherford G, Mermin J: Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural Uganda. Aids 2006,20(1):85–92.PubMedCrossRef
47.
go back to reference Luchters S, Sarna A, Geibel S, Chersich MF, Munyao P, Kaai S, Mandaliya KN, Shikely KS, Rutenberg N, Temmerman M: Safer sexual behaviors after 12 months of antiretroviral treatment in Mombasa, Kenya: a prospective cohort. AIDS Patient Care STDS 2008,22(7):587–94.PubMedCrossRef Luchters S, Sarna A, Geibel S, Chersich MF, Munyao P, Kaai S, Mandaliya KN, Shikely KS, Rutenberg N, Temmerman M: Safer sexual behaviors after 12 months of antiretroviral treatment in Mombasa, Kenya: a prospective cohort. AIDS Patient Care STDS 2008,22(7):587–94.PubMedCrossRef
Metadata
Title
Sexual risk taking among patients on antiretroviral therapy in an urban informal settlement in Kenya: a cross-sectional survey
Authors
Anders Ragnarsson
Anna Mia Ekström
Jane Carter
Festus Ilako
Abigail Lukhwaro
Gaetano Marrone
Anna Thorson
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of the International AIDS Society / Issue 1/2011
Electronic ISSN: 1758-2652
DOI
https://doi.org/10.1186/1758-2652-14-20

Other articles of this Issue 1/2011

Journal of the International AIDS Society 1/2011 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine