Skip to main content
Top
Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2013

Open Access 01-12-2013 | Original research

Comparison between laparotomy first versus angiographic embolization first in patients with pelvic fracture and hemoperitoneum: a nationwide observational study from the Japan Trauma Data Bank

Authors: Morihiro Katsura, Shin Yamazaki, Shingo Fukuma, Kazuhide Matsushima, Toshimitsu Yamashiro, Shunichi Fukuhara

Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Issue 1/2013

Login to get access

Abstract

Background

A common dilemma in the management of pelvic fractures is recognizing the presence of associated abdominal injury. The purpose of this study was to determine the association between initial therapeutic intervention (laparotomy or transcatheter arterial embolization (TAE)) and mortality.

Methods

This was a cohort study using the Japan Trauma Data Bank between 2004 and 2010, including blunt trauma patients with pelvic fractures and positive Focused Assessment with Sonography in Trauma (FAST) results. Eligible patients were restricted to those who underwent laparotomy or TAE/angiography as the initial therapeutic intervention. Crude and adjusted odds ratio (AOR) for in-hospital mortality were compared between the laparotomy first and TAE first groups (reference group). Multiple logistic regression analysis and propensity score adjusted analysis were used to adjust for clinically relevant confounders, including the severity of injury.

Results

Of the 317 participants, 123 patients underwent laparotomy first and 194 patients underwent TAE first. The two groups were similar in terms of age, although the laparotomy first group had higher mean Injury Severity Scores (ISS) and higher mean scores based on the abdominal Abbreviated Injury Scale (AIS), as well as lower mean pelvic AIS and systolic blood pressure (SBP). Half of the patients who were hypotensive (SBP < 90 mmHg) on arrival underwent TAE first. The laparotomy first group had a significantly higher crude in-hospital mortality (41% vs. 27%; P < 0.01). After adjusting for confounders, the choice of initial therapeutic intervention did not affect the in-hospital mortality (AOR, 1.20; 95% Confidence Interval (CI), 0.61-2.39). Even in the limited subgroup of hypotensive patients (SBP 66–89 mmHg and SBP < 65 mmHg subgroup), the effect was similar (AOR, 1.50; 95% CI, 0.56-4.05 and AOR, 1.05; 95% CI, 0.44-3.03).

Conclusions

In Japan, laparotomy and TAE are equally chosen as the initial therapeutic intervention regardless of hemodynamic status. No significant difference was seen between the laparotomy first and TAE first groups regarding in-hospital mortality.
Appendix
Available only for authorised users
Literature
1.
go back to reference Ruchholtz S, Waydhas C, Lewan U, Pehle B, Taeger G, Kühne C, Nast-Kolb D: Free abdominal fluid on ultrasound in unstable pelvic ring fracture: is laparotomy always necessary?. J Trauma. 2004, 57: 278-285. 10.1097/01.TA.0000133840.44265.CA.CrossRefPubMed Ruchholtz S, Waydhas C, Lewan U, Pehle B, Taeger G, Kühne C, Nast-Kolb D: Free abdominal fluid on ultrasound in unstable pelvic ring fracture: is laparotomy always necessary?. J Trauma. 2004, 57: 278-285. 10.1097/01.TA.0000133840.44265.CA.CrossRefPubMed
2.
go back to reference Murr PC, Moore EE, Lipscomb R, Johnston RM: Abdominal trauma associated with pelvic fracture. J Trauma. 1980, 20: 919-923. 10.1097/00005373-198011000-00001.CrossRefPubMed Murr PC, Moore EE, Lipscomb R, Johnston RM: Abdominal trauma associated with pelvic fracture. J Trauma. 1980, 20: 919-923. 10.1097/00005373-198011000-00001.CrossRefPubMed
3.
go back to reference Ben-Menachem Y, Coldwell DM, Young JW, Burgess AR: Hemorrhage associated with pelvic fractures: causes, diagnosis, and emergent management. AJR Am J Roentgenol. 1991, 157: 1005-1014. 10.2214/ajr.157.5.1927786.CrossRefPubMed Ben-Menachem Y, Coldwell DM, Young JW, Burgess AR: Hemorrhage associated with pelvic fractures: causes, diagnosis, and emergent management. AJR Am J Roentgenol. 1991, 157: 1005-1014. 10.2214/ajr.157.5.1927786.CrossRefPubMed
4.
go back to reference Fu CY, Wang YC, Wu SC, Chen RJ, Hsieh CH, Huang HC, Huang JC, Lu CW, Huang YC: Angioembolization provides benefits in patients with concomitant unstable pelvic fracture and unstable hemodynamics. Am J Emerg Med. 2012, 30: 207-213. 10.1016/j.ajem.2010.11.005.CrossRefPubMed Fu CY, Wang YC, Wu SC, Chen RJ, Hsieh CH, Huang HC, Huang JC, Lu CW, Huang YC: Angioembolization provides benefits in patients with concomitant unstable pelvic fracture and unstable hemodynamics. Am J Emerg Med. 2012, 30: 207-213. 10.1016/j.ajem.2010.11.005.CrossRefPubMed
5.
go back to reference Cullinane DC, Schiller HJ, Zielinski MD, Bilaniuk JW, Collier BR, Como J, Holevar M, Sabater EA, Sems SA, Vassy WM, Wynne JL: Eastern association for the surgery of trauma practice management guidelines for hemorrhage in pelvic fracture-update and systematic review. J Trauma. 2011, 71: 1850-1868. 10.1097/TA.0b013e31823dca9a.CrossRefPubMed Cullinane DC, Schiller HJ, Zielinski MD, Bilaniuk JW, Collier BR, Como J, Holevar M, Sabater EA, Sems SA, Vassy WM, Wynne JL: Eastern association for the surgery of trauma practice management guidelines for hemorrhage in pelvic fracture-update and systematic review. J Trauma. 2011, 71: 1850-1868. 10.1097/TA.0b013e31823dca9a.CrossRefPubMed
6.
go back to reference Geeraerts T, Chhor V, Cheisson G, Martin L, Bessoud B, Ozanne A, Duranteau J: Clinical review: initial management of blunt pelvic trauma patients with haemodynamic instability. Crit Care. 2007, 11: 204-10.1186/cc5157.PubMedCentralCrossRefPubMed Geeraerts T, Chhor V, Cheisson G, Martin L, Bessoud B, Ozanne A, Duranteau J: Clinical review: initial management of blunt pelvic trauma patients with haemodynamic instability. Crit Care. 2007, 11: 204-10.1186/cc5157.PubMedCentralCrossRefPubMed
7.
go back to reference Eastridge BJ, Starr A, Minei JP, O’Keefe GE, Scalea TM: The importance of fracture pattern in guiding therapeutic decision-making in patients with hemorrhagic shock and pelvic ring disruptions. J Trauma. 2002, 53: 446-450. 10.1097/00005373-200209000-00009.CrossRefPubMed Eastridge BJ, Starr A, Minei JP, O’Keefe GE, Scalea TM: The importance of fracture pattern in guiding therapeutic decision-making in patients with hemorrhagic shock and pelvic ring disruptions. J Trauma. 2002, 53: 446-450. 10.1097/00005373-200209000-00009.CrossRefPubMed
8.
go back to reference Hagiwara A, Minakawa K, Fukushima H, Murata A, Masuda H, Shimazaki S: Predictors of death in patients with life-threatening pelvic hemorrhage after successful transcatheter arterial embolization. J Trauma. 2003, 55: 696-703. 10.1097/01.TA.0000053384.85091.C6.CrossRefPubMed Hagiwara A, Minakawa K, Fukushima H, Murata A, Masuda H, Shimazaki S: Predictors of death in patients with life-threatening pelvic hemorrhage after successful transcatheter arterial embolization. J Trauma. 2003, 55: 696-703. 10.1097/01.TA.0000053384.85091.C6.CrossRefPubMed
9.
go back to reference Thorson CM, Ryan ML, Otero CA, Vu T, Borja MJ, Jose J, Schulman CI, Livingstone AS, Proctor KG: Operating room or angiography suite for hemodynamically unstable pelvic fractures?. J Trauma. 2012, 72: 364-372.CrossRef Thorson CM, Ryan ML, Otero CA, Vu T, Borja MJ, Jose J, Schulman CI, Livingstone AS, Proctor KG: Operating room or angiography suite for hemodynamically unstable pelvic fractures?. J Trauma. 2012, 72: 364-372.CrossRef
10.
go back to reference Shoko T, Shiraishi A, Kaji M, Otomo Y: Effect of pre-existing medical conditions on in-hospital mortality: analysis of 20,257 trauma patients in Japan. J Am Coll Surg. 2010, 211: 338-346. 10.1016/j.jamcollsurg.2010.04.010.CrossRefPubMed Shoko T, Shiraishi A, Kaji M, Otomo Y: Effect of pre-existing medical conditions on in-hospital mortality: analysis of 20,257 trauma patients in Japan. J Am Coll Surg. 2010, 211: 338-346. 10.1016/j.jamcollsurg.2010.04.010.CrossRefPubMed
11.
go back to reference Kimura A, Nakahara S, Chadbunchachai W: The development of simple survival prediction models for blunt trauma victims treated at Asian emergency centers. Scand J Trauma Resusc Emerg Med. 2012, 20: 9-10.1186/1757-7241-20-9.PubMedCentralCrossRefPubMed Kimura A, Nakahara S, Chadbunchachai W: The development of simple survival prediction models for blunt trauma victims treated at Asian emergency centers. Scand J Trauma Resusc Emerg Med. 2012, 20: 9-10.1186/1757-7241-20-9.PubMedCentralCrossRefPubMed
12.
go back to reference Kimura A, Tanaka N: Whole-body computed tomography is associated with decreased mortality in blunt trauma patients with moderate-to-severe consciousness disturbance: a multicenter, retrospective study. J Trauma Acute Care Surg. 2013, 75: 202-206. 10.1097/TA.0b013e3182905ef7.CrossRefPubMed Kimura A, Tanaka N: Whole-body computed tomography is associated with decreased mortality in blunt trauma patients with moderate-to-severe consciousness disturbance: a multicenter, retrospective study. J Trauma Acute Care Surg. 2013, 75: 202-206. 10.1097/TA.0b013e3182905ef7.CrossRefPubMed
13.
go back to reference Tohira H, Jacobs I, Matsuoka T, Ishikawa K: Impact of the version of the abbreviated injury scale on injury severity characterization and quality assessment of trauma care. J Trauma. 2011, 71: 56-62. 10.1097/TA.0b013e31821e5a25.CrossRefPubMed Tohira H, Jacobs I, Matsuoka T, Ishikawa K: Impact of the version of the abbreviated injury scale on injury severity characterization and quality assessment of trauma care. J Trauma. 2011, 71: 56-62. 10.1097/TA.0b013e31821e5a25.CrossRefPubMed
14.
go back to reference Niwa T, Takebayashi S, Igari H, Morimura N, Uchida K, Sugiyama M, Matsubara S: The value of plain radiographs in the prediction of outcome in pelvic fractures treated with embolisation therapy. Br J Radiol. 2000, 73: 945-950.CrossRefPubMed Niwa T, Takebayashi S, Igari H, Morimura N, Uchida K, Sugiyama M, Matsubara S: The value of plain radiographs in the prediction of outcome in pelvic fractures treated with embolisation therapy. Br J Radiol. 2000, 73: 945-950.CrossRefPubMed
15.
go back to reference Kimbrell BJ, Velmahos GC, Chan LS, Demetriades D: Angiographic embolization for pelvic fractures in older patients. Arch Surg. 2004, 139: 728-732. 10.1001/archsurg.139.7.728.CrossRefPubMed Kimbrell BJ, Velmahos GC, Chan LS, Demetriades D: Angiographic embolization for pelvic fractures in older patients. Arch Surg. 2004, 139: 728-732. 10.1001/archsurg.139.7.728.CrossRefPubMed
16.
go back to reference Pohlemann T, Stengel D, Tosounidis G, Reilmann H, Stuby F, Stöckle U, Seekamp A, Schmal H, Thannheimer A, Holmenschlager F, Gänsslen A, Rommens PM, Fuchs T, Baumgärtel F, Marintschev I, Krischak G, Wunder S, Tscherne H, Culemann U: Survival trends and predictors of mortality in severe pelvic trauma: estimates from the German pelvic trauma registry initiative. Injury. 2011, 42: 997-1002. 10.1016/j.injury.2011.03.053.CrossRefPubMed Pohlemann T, Stengel D, Tosounidis G, Reilmann H, Stuby F, Stöckle U, Seekamp A, Schmal H, Thannheimer A, Holmenschlager F, Gänsslen A, Rommens PM, Fuchs T, Baumgärtel F, Marintschev I, Krischak G, Wunder S, Tscherne H, Culemann U: Survival trends and predictors of mortality in severe pelvic trauma: estimates from the German pelvic trauma registry initiative. Injury. 2011, 42: 997-1002. 10.1016/j.injury.2011.03.053.CrossRefPubMed
17.
go back to reference Burkhardt M, Nienaber U, Pizanis A, Maegele M, Culemann U, Bouillon B, Flohé S, Pohlemann T, Paffrath X, the TraumaRegister DGU and the German Pelvic Injury Register of the Deutsche Gesellschaft für Unfallchirurgie: Acute management and outcome of multiple trauma patients with pelvic disruptions. Crit Care. 2012, 16: R163-10.1186/cc11487.PubMedCentralCrossRefPubMed Burkhardt M, Nienaber U, Pizanis A, Maegele M, Culemann U, Bouillon B, Flohé S, Pohlemann T, Paffrath X, the TraumaRegister DGU and the German Pelvic Injury Register of the Deutsche Gesellschaft für Unfallchirurgie: Acute management and outcome of multiple trauma patients with pelvic disruptions. Crit Care. 2012, 16: R163-10.1186/cc11487.PubMedCentralCrossRefPubMed
18.
go back to reference Hagiwara A, Murata A, Matsura T, Shimazaki S: The usefulness of transcatheter embolization for patients with blunt polytrauma showing transient response to fluid resuscitation. J Trauma. 2004, 57: 271-276. 10.1097/01.TA.0000131198.79153.3C.CrossRefPubMed Hagiwara A, Murata A, Matsura T, Shimazaki S: The usefulness of transcatheter embolization for patients with blunt polytrauma showing transient response to fluid resuscitation. J Trauma. 2004, 57: 271-276. 10.1097/01.TA.0000131198.79153.3C.CrossRefPubMed
19.
go back to reference Malhotra AK, Fanbian TC, Croce MA, Gavin TJ, Kudsk KA, Minard G, Pritchard FE: Blunt hepatic injury: a paradigm shift from operative to nonoperative management in the 1990s. Ann Surg. 2000, 231: 804-813. 10.1097/00000658-200006000-00004.PubMedCentralCrossRefPubMed Malhotra AK, Fanbian TC, Croce MA, Gavin TJ, Kudsk KA, Minard G, Pritchard FE: Blunt hepatic injury: a paradigm shift from operative to nonoperative management in the 1990s. Ann Surg. 2000, 231: 804-813. 10.1097/00000658-200006000-00004.PubMedCentralCrossRefPubMed
20.
go back to reference Raikhlin A, Baerlocher MO, Aschi MR, Myers A: Imaging and transcatheter arterial embolization for traumatic splenic injuries: review of the literature. Can J Surg. 2008, 51: 464-472.PubMedCentralPubMed Raikhlin A, Baerlocher MO, Aschi MR, Myers A: Imaging and transcatheter arterial embolization for traumatic splenic injuries: review of the literature. Can J Surg. 2008, 51: 464-472.PubMedCentralPubMed
21.
go back to reference Grimm MR, Vrahas MS, Thomas KA: Pressure-volume characteristics of the intact and disrupted pelvic retroperitoneum. J Trauma. 1998, 44: 454-459. 10.1097/00005373-199803000-00006.CrossRefPubMed Grimm MR, Vrahas MS, Thomas KA: Pressure-volume characteristics of the intact and disrupted pelvic retroperitoneum. J Trauma. 1998, 44: 454-459. 10.1097/00005373-199803000-00006.CrossRefPubMed
22.
go back to reference Kondo Y, Abe T, Kohshi K, Tokuda Y, Cook EF, Kukita I: Revised trauma scoring system to predict in-hospital mortality in the emergency department: Glasgow Coma Scale, Age, and Systolic Blood Pressure score. Crit Care. 2011, 15: R191-10.1186/cc10348.PubMedCentralCrossRefPubMed Kondo Y, Abe T, Kohshi K, Tokuda Y, Cook EF, Kukita I: Revised trauma scoring system to predict in-hospital mortality in the emergency department: Glasgow Coma Scale, Age, and Systolic Blood Pressure score. Crit Care. 2011, 15: R191-10.1186/cc10348.PubMedCentralCrossRefPubMed
23.
go back to reference Ballard RB, Rozycki GS, Newman PG, Cubillos JE, Salomone JP, Ingram WL, Feliciano DV: An algorithm to reduce the incidence of false-negative FAST examinations in patients at high risk for occult injury. Focused assessment for the sonographic examination of the trauma patient. J Am Coll Surg. 1999, 189: 145-150. 10.1016/S1072-7515(99)00121-0.CrossRefPubMed Ballard RB, Rozycki GS, Newman PG, Cubillos JE, Salomone JP, Ingram WL, Feliciano DV: An algorithm to reduce the incidence of false-negative FAST examinations in patients at high risk for occult injury. Focused assessment for the sonographic examination of the trauma patient. J Am Coll Surg. 1999, 189: 145-150. 10.1016/S1072-7515(99)00121-0.CrossRefPubMed
24.
go back to reference Osborn PM, Smith WR, Moore EE, Cothren CC, Morgan SJ, Williams AE, Stahel PF: Direct retroperitoneal pelvic packing versus pelvic angiography: a comparison of two management protocols for haemodynamically unstable pelvic fractures. Injury. 2009, 40: 54-60. 10.1016/j.injury.2008.08.038.CrossRefPubMed Osborn PM, Smith WR, Moore EE, Cothren CC, Morgan SJ, Williams AE, Stahel PF: Direct retroperitoneal pelvic packing versus pelvic angiography: a comparison of two management protocols for haemodynamically unstable pelvic fractures. Injury. 2009, 40: 54-60. 10.1016/j.injury.2008.08.038.CrossRefPubMed
25.
go back to reference Cothren CC, Osborn PM, Moore EE, Morgan SJ, Johnson JL, Smith WR: Preperitonal pelvic packing for hemodynamically unstable pelvic fractures: a paradigm shift. J Trauma. 2007, 62: 834-839. 10.1097/TA.0b013e31803c7632.CrossRefPubMed Cothren CC, Osborn PM, Moore EE, Morgan SJ, Johnson JL, Smith WR: Preperitonal pelvic packing for hemodynamically unstable pelvic fractures: a paradigm shift. J Trauma. 2007, 62: 834-839. 10.1097/TA.0b013e31803c7632.CrossRefPubMed
26.
go back to reference Burlew CC, Moore EE, Smith WR, Johnson JL, Biffl WL, Barnett CC, Stahel PF: Preperitoneal pelvic packing/external fixation with secondary angioembolization: optimal care for life-threatening hemorrhage from unstable pelvic fractures. J Am Coll Surg. 2011, 212: 628-635. 10.1016/j.jamcollsurg.2010.12.020.CrossRefPubMed Burlew CC, Moore EE, Smith WR, Johnson JL, Biffl WL, Barnett CC, Stahel PF: Preperitoneal pelvic packing/external fixation with secondary angioembolization: optimal care for life-threatening hemorrhage from unstable pelvic fractures. J Am Coll Surg. 2011, 212: 628-635. 10.1016/j.jamcollsurg.2010.12.020.CrossRefPubMed
27.
go back to reference Morozumi J, Homma H, Ohta S, Noda M, Oda J, Mishima S, Yukioka T: Impact of mobile angiography in the emergency department for controlling pelvic fracture hemorrhage with hemodynamic instability. J Trauma. 2010, 68: 90-95. 10.1097/TA.0b013e3181c40061.CrossRefPubMed Morozumi J, Homma H, Ohta S, Noda M, Oda J, Mishima S, Yukioka T: Impact of mobile angiography in the emergency department for controlling pelvic fracture hemorrhage with hemodynamic instability. J Trauma. 2010, 68: 90-95. 10.1097/TA.0b013e3181c40061.CrossRefPubMed
Metadata
Title
Comparison between laparotomy first versus angiographic embolization first in patients with pelvic fracture and hemoperitoneum: a nationwide observational study from the Japan Trauma Data Bank
Authors
Morihiro Katsura
Shin Yamazaki
Shingo Fukuma
Kazuhide Matsushima
Toshimitsu Yamashiro
Shunichi Fukuhara
Publication date
01-12-2013
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1757-7241-21-82

Other articles of this Issue 1/2013

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2013 Go to the issue