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Open Access 01-12-2010 | Review

Treatment options for patients with triple-negative breast cancer

Authors: Rafael Santana-Davila, Edith A Perez

Published in: Journal of Hematology & Oncology | Issue 1/2010

Abstract

Breast cancer is a heterogeneous disease composed of different subtypes, characterized by their different clinicopathological characteristics, prognoses and responses to treatment. In the past decade, significant advances have been made in the treatment of breast cancer sensitive to hormonal treatments, as well as in patients whose malignant cells overexpress or amplify HER2. In contrast, mainly due to the lack of molecular targets, little progress has been made in the treatment of patients with triple-negative breast cancer. Recent improved understanding of the natural history, pathophysiology, and molecular features of triple-negative breast cancers have provided new insights into management and therapeutic strategies for women affected with this entity. Ongoing and planned translational clinical trials are likely to optimize and improve treatment of women with this disease.

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Title: Treatment options for patients with triple-negative breast cancer
Authors: Rafael Santana-Davila
Edith A Perez
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Journal of Hematology & Oncology / Issue 1/2010
Electronic ISSN: 1756-8722
DOI: https://doi.org/10.1186/1756-8722-3-42

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