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Thyroid Research

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Open Access 01-12-2012 | Case report

Cholestatic hepatic injury due to a thyroid storm: a case report from a resource limited setting

Authors: Davis Kibirige, Daniel Sekikubo Kiggundu, Richard Sanya, Edrisa Mutebi

Published in: Thyroid Research | Issue 1/2012

Abstract

Introduction

Thyroid storm is an endocrinological emergency caused by an exacerbation of the hyperthyroid state and is characterized by multi organ dysfunction. Liver dysfunction or injury predominantly of a cholestatic type is one of the atypical manifestations of thyroid storm and has been previously described in literature. However, there have been few published case reports among African patients and from resource limited settings.

Case report

We report a case of a 21 year old Ugandan female patient who presented with a thyroid storm due to untreated Graves’ disease complicated by cholestatic hepatic injury, congestive heart failure and acute kidney injury.

Conclusion

This case highlights the varied multi organ dysfunctions seen in a patient with thyroid storm with emphasis on liver injury mainly to increase awareness among clinicians in resource limited settings. Mechanisms of liver injury due to thyroid storm or hyperthyroidism are discussed in the literature review.

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Title: Cholestatic hepatic injury due to a thyroid storm: a case report from a resource limited setting
Authors: Davis Kibirige
Daniel Sekikubo Kiggundu
Richard Sanya
Edrisa Mutebi
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Thyroid Research / Issue 1/2012
Electronic ISSN: 1756-6614
DOI: https://doi.org/10.1186/1756-6614-5-6

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Introduction

Case report

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