Published in:
Open Access
01-12-2012 | Review
Caspases in synaptic plasticity
Authors:
Zheng Li, Morgan Sheng
Published in:
Molecular Brain
|
Issue 1/2012
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Abstract
Caspases are a family of cysteine proteases that play key roles in programmed cell death (apoptosis). Mounting evidence in recent years shows that caspases also have important non-apoptotic functions in multiple cellular processes, such as synaptic plasticity, dendritic development, learning and memory. In this article, we review the studies on the non-apoptotic functions of caspases in neurons, with a focus on their roles in synaptic plasticity, learning and memory and neurodegeneration.