Published in:
Open Access
01-12-2011 | Case report
Spindle cell oncocytoma of the adenohypophysis in a woman: a case report and review of the literature
Authors:
M Mlika, H Azouz, I Chelly, I Ben Saïd, H Jemel, S Haouet, M Zitouna, N Kchir
Published in:
Journal of Medical Case Reports
|
Issue 1/2011
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Abstract
Introduction
Spindle cell oncocytoma of the adenohypophysis is a rare tumour recently reported by Roncaroli et al. in 2002. This tumour is considered a grade I tumour by the World Health Organization.
Case presentation
We describe what is, to the best of our knowledge, the 14th case of its kind in the literature. A 45-year-old African woman presented clinical and radiological findings related to a nonfunctioning pituitary adenoma. The diagnosis was made on the basis of histological and immunohistochemical findings.
Conclusion
The purpose of this work is to report a rare pituitary tumour and to describe its histological and immunohistochemical features, which were characterized by the expression of thyroid transcription factor 1 antigen by tumour cells. This fact could support the theory of a possible common origin of these tumours in pituicytomas. In fact, thyroid transcription factor 1 is considered to be a specific marker of pituicytes.