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Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2011

Open Access 01-12-2011 | Case report

Intrathecal injection of human umbilical cord blood-derived mesenchymal stem cells for the treatment of basilar artery dissection: a case report

Authors: Hoon Han, Sang-Keun Chang, Jennifer J Chang, Soo-Han Hwang, Seung-Hyup Han, Bok-Hwan Chun

Published in: Journal of Medical Case Reports | Issue 1/2011

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Abstract

Introduction

Basilar artery dissection is a rare occurrence, and is significantly associated with morbidity and mortality. To the best of our knowledge, we report the first case of basilar artery dissection treated with mesenchymal stem cells.

Case presentation

We present the case of a 17-year-old Korean man who was diagnosed with basilar artery dissection. Infarction of the bilateral pons, midbrain and right superior cerebellum due to his basilar artery dissection was partially recanalized by intrathecal injection of human umbilical cord blood-derived mesenchymal stem cells. No immunosuppressants were given to our patient, and human leukocyte antigen alloantibodies were not detected after cell therapy.

Conclusions

This case indicates that intrathecal injections of mesenchymal stem cells can be used in the treatment of basilar artery dissection.
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Metadata
Title
Intrathecal injection of human umbilical cord blood-derived mesenchymal stem cells for the treatment of basilar artery dissection: a case report
Authors
Hoon Han
Sang-Keun Chang
Jennifer J Chang
Soo-Han Hwang
Seung-Hyup Han
Bok-Hwan Chun
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-5-562

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