Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2011

Open Access 01-12-2011 | Research article

Secondary omental and pectoralis major double flap reconstruction following aggressive sternectomy for deep sternal wound infections after cardiac surgery

Authors: Toshiro Kobayashi, Akihito Mikamo, Hiroshi Kurazumi, Ryo Suzuki, Bungo Shirasawa, Kimikazu Hamano

Published in: Journal of Cardiothoracic Surgery | Issue 1/2011

Login to get access

Abstract

Background

Deep sternal wound infection after cardiac surgery carries high morbidity and mortality. Our strategy for deep sternal wound infection is aggressive strenal debridement followed by vacuum-assisted closure (VAC) therapy and omental-muscle flap reconstrucion. We describe this strategy and examine the outcome and long-term quality of life (QOL) it achieves.

Methods

We retrospectively examined 16 patients treated for deep sternal wound infection between 2001 and 2007. The most recent nine patients were treated with total sternal resection followed by VAC therapy and secondary closure with omental-muscle flap reconstruction (recent group); whereas the former seven patients were treated with sternal preservation if possible, without VAC therapy, and four of these patients underwent primary closure (former group). We assessed long-term quality of life after DSWI by using the Short Form 36-Item Health Survey, Version 2 (SF36v2).

Results

One patient died and four required further surgery for recurrence of deep sternal wound infection in the former group. The duration of treatment for deep sternal wound infection in the recent group was significantly shorter than that in previous group (63.4 ± 54.1 days vs. 120.0 ± 31.8 days, respectively; p = 0.039). Despite aggressive sternal resection, the QOL of patients treated for DSWI was only minimally compromised compared with age-, sex-, surgical procedures-matched patients without deep sternal wound infection.

Conclusions

Aggressive sternal debridement followed by VAC therapy and secondary closure with an omental-muscle flap is effective for deep sternal wound infection. In this series, it resulted in a lower incidence of recurrent infection, shorter hospitalization, and it did not compromise long-term QOL greatly.
Appendix
Available only for authorised users
Literature
1.
go back to reference Shumacker HB, Mandelbaum I: Continuous antibiotic irrigation in the treatment of infection. Arch Surg. 1963, 86: 384-387.CrossRefPubMed Shumacker HB, Mandelbaum I: Continuous antibiotic irrigation in the treatment of infection. Arch Surg. 1963, 86: 384-387.CrossRefPubMed
2.
go back to reference Jurkiewicz MJ, Bostwick J, Hester TR, Bishop JB, Craver J: Infected median sternotomy wound. Successful treatment by muscle flaps. Ann Surg. 1980, 191: 738-744. 10.1097/00000658-198006000-00012.CrossRefPubMedPubMedCentral Jurkiewicz MJ, Bostwick J, Hester TR, Bishop JB, Craver J: Infected median sternotomy wound. Successful treatment by muscle flaps. Ann Surg. 1980, 191: 738-744. 10.1097/00000658-198006000-00012.CrossRefPubMedPubMedCentral
3.
go back to reference Klesius AA, Dzemali O, Simon A, Kleine P, Abdel-Rahman U, Herzog C, Wimmer-Greinecker G, Moritz A: Successful treatment of deep sternal infections following open heart surgery by bilateral pectoralis major flaps. Eur J Cardiothorac Surg. 2004, 25: 218-223. 10.1016/j.ejcts.2003.11.019.CrossRefPubMed Klesius AA, Dzemali O, Simon A, Kleine P, Abdel-Rahman U, Herzog C, Wimmer-Greinecker G, Moritz A: Successful treatment of deep sternal infections following open heart surgery by bilateral pectoralis major flaps. Eur J Cardiothorac Surg. 2004, 25: 218-223. 10.1016/j.ejcts.2003.11.019.CrossRefPubMed
4.
go back to reference Colen LB, Huntsman WT, Morain WD: The integrated approach to suppurative mediastinitis: rewiring the sternum over transposed omentum. Plast Reconstr Surg. 1989, 84: 936-941. 10.1097/00006534-198912000-00011. discussion 942-943CrossRefPubMed Colen LB, Huntsman WT, Morain WD: The integrated approach to suppurative mediastinitis: rewiring the sternum over transposed omentum. Plast Reconstr Surg. 1989, 84: 936-941. 10.1097/00006534-198912000-00011. discussion 942-943CrossRefPubMed
5.
go back to reference Yasuura K, Okamoto H, Morita S, Ogawa Y, Sawazaki M, Seki A, Masumoto H, Matsuura A, Maseki T, Torii S: Results of omental flap transposition for deep sternal wound infection after cardiovascular surgery. Ann Surg. 1998, 227: 455-459. 10.1097/00000658-199803000-00019.CrossRefPubMedPubMedCentral Yasuura K, Okamoto H, Morita S, Ogawa Y, Sawazaki M, Seki A, Masumoto H, Matsuura A, Maseki T, Torii S: Results of omental flap transposition for deep sternal wound infection after cardiovascular surgery. Ann Surg. 1998, 227: 455-459. 10.1097/00000658-199803000-00019.CrossRefPubMedPubMedCentral
6.
go back to reference Lovich SF, Iverson LI, Young JN, Ennix CL, Harrell JE, Ecker RR, Lau G, Joseph P, May IA: Omental pedicle grafting in the treatment of postcardiotomy sternotomy infection. Arch Surg. 1989, 124: 1192-1194.CrossRefPubMed Lovich SF, Iverson LI, Young JN, Ennix CL, Harrell JE, Ecker RR, Lau G, Joseph P, May IA: Omental pedicle grafting in the treatment of postcardiotomy sternotomy infection. Arch Surg. 1989, 124: 1192-1194.CrossRefPubMed
7.
go back to reference Hollenbeak CS, Murphy DM, Koenig S, Woodward RS, Dunagan WC, Fraser VJ: The clinical and economic impact of deep chest surgical site infections following coronary artery bypass graft surgery. Chest. 2000, 118: 397-402. 10.1378/chest.118.2.397.CrossRefPubMed Hollenbeak CS, Murphy DM, Koenig S, Woodward RS, Dunagan WC, Fraser VJ: The clinical and economic impact of deep chest surgical site infections following coronary artery bypass graft surgery. Chest. 2000, 118: 397-402. 10.1378/chest.118.2.397.CrossRefPubMed
8.
go back to reference Jenney AW, Harrington GA, Russo PL, Spelman DW: Cost of surgical site infections following coronary artery bypass surgery. ANZ J Surg. 2001, 71: 662-664. 10.1046/j.1445-1433.2001.02225.x.CrossRefPubMed Jenney AW, Harrington GA, Russo PL, Spelman DW: Cost of surgical site infections following coronary artery bypass surgery. ANZ J Surg. 2001, 71: 662-664. 10.1046/j.1445-1433.2001.02225.x.CrossRefPubMed
9.
go back to reference Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W: Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997, 38: 553-562. 10.1097/00000637-199706000-00001.CrossRefPubMed Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W: Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997, 38: 553-562. 10.1097/00000637-199706000-00001.CrossRefPubMed
10.
go back to reference Argenta LC, Morykwas MJ: Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997, 38: 563-576. 10.1097/00000637-199706000-00002. discussion 577CrossRefPubMed Argenta LC, Morykwas MJ: Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997, 38: 563-576. 10.1097/00000637-199706000-00002. discussion 577CrossRefPubMed
11.
go back to reference Obdeijn MC, de Lange MY, Lichtendahl DH, de Boer WJ: Vacuum-assisted closure in the treatment of poststernotomy mediastinitis. Ann Thorac Surg. 1999, 68: 2358-2360. 10.1016/S0003-4975(99)01159-5.CrossRefPubMed Obdeijn MC, de Lange MY, Lichtendahl DH, de Boer WJ: Vacuum-assisted closure in the treatment of poststernotomy mediastinitis. Ann Thorac Surg. 1999, 68: 2358-2360. 10.1016/S0003-4975(99)01159-5.CrossRefPubMed
12.
go back to reference El Oakley RM, Wright JE: Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996, 61: 1030-1036. 10.1016/0003-4975(95)01035-1.CrossRefPubMed El Oakley RM, Wright JE: Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996, 61: 1030-1036. 10.1016/0003-4975(95)01035-1.CrossRefPubMed
13.
go back to reference Milano CA, Kesler K, Archibald N, Sexton DJ, Jones RH: Mediastinitis After Coronary Artery Bypass Graft Surgery. Circulation. 1995, 92: 2245-2251.CrossRefPubMed Milano CA, Kesler K, Archibald N, Sexton DJ, Jones RH: Mediastinitis After Coronary Artery Bypass Graft Surgery. Circulation. 1995, 92: 2245-2251.CrossRefPubMed
14.
go back to reference Luckraz H, Murphy F, Bryant S, Charman SC, Ritchie AJ: Vacuum-assisted closure as a treatment modality for infections after cardiac surgery. J Thorac Cardiovasc Surg. 2003, 125: 301-305. 10.1067/mtc.2003.74.CrossRefPubMed Luckraz H, Murphy F, Bryant S, Charman SC, Ritchie AJ: Vacuum-assisted closure as a treatment modality for infections after cardiac surgery. J Thorac Cardiovasc Surg. 2003, 125: 301-305. 10.1067/mtc.2003.74.CrossRefPubMed
15.
go back to reference Fukuhara S, Bito S, Green J, Hsiao A, Kurokawa K: Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol. 1998, 51: 1037-1044. 10.1016/S0895-4356(98)00095-X.CrossRefPubMed Fukuhara S, Bito S, Green J, Hsiao A, Kurokawa K: Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol. 1998, 51: 1037-1044. 10.1016/S0895-4356(98)00095-X.CrossRefPubMed
16.
go back to reference Fukuhara S, Ware JE, Kosinski M, Wada S, Gandek B: Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol. 1998, 51: 1045-1053. 10.1016/S0895-4356(98)00096-1.CrossRefPubMed Fukuhara S, Ware JE, Kosinski M, Wada S, Gandek B: Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol. 1998, 51: 1045-1053. 10.1016/S0895-4356(98)00096-1.CrossRefPubMed
17.
go back to reference Fukuhara S, Suzukamo Y: Manual of SF-36v2 Japanese version: Institute for Health Outcomes & Process Evaluation Research, Kyoto. 2004 Fukuhara S, Suzukamo Y: Manual of SF-36v2 Japanese version: Institute for Health Outcomes & Process Evaluation Research, Kyoto. 2004
18.
go back to reference Schroeyers P, Wellens F, Degrieck I, De Geest R, Van Praet F, Vermeulen Y, Vanermen H: Aggressive primary treatment for poststernotomy acute mediastinitis: our experience with omental- and muscle flaps surgery. Eur J Cardiothorac Surg. 2001, 20: 743-746. 10.1016/S1010-7940(01)00873-9.CrossRefPubMed Schroeyers P, Wellens F, Degrieck I, De Geest R, Van Praet F, Vermeulen Y, Vanermen H: Aggressive primary treatment for poststernotomy acute mediastinitis: our experience with omental- and muscle flaps surgery. Eur J Cardiothorac Surg. 2001, 20: 743-746. 10.1016/S1010-7940(01)00873-9.CrossRefPubMed
19.
go back to reference Fleck TM, Koller R, Giovanoli P, Moidl R, Czerny M, Fleck M, Wolner E, Grabenwoger M: Primary or delayed closure for the treatment of poststernotomy wound infections?. Ann Plast Surg. 2004, 52: 310-314. 10.1097/01.sap.0000105524.75597.e0.CrossRefPubMed Fleck TM, Koller R, Giovanoli P, Moidl R, Czerny M, Fleck M, Wolner E, Grabenwoger M: Primary or delayed closure for the treatment of poststernotomy wound infections?. Ann Plast Surg. 2004, 52: 310-314. 10.1097/01.sap.0000105524.75597.e0.CrossRefPubMed
20.
go back to reference Lindsey JT: A retrospective analysis of 48 infected sternal wound closures: delayed closure decreases wound complications. Plast Reconstr Surg. 2002, 109: 1882-1885. 10.1097/00006534-200205000-00015. discussion 1886-1887CrossRefPubMed Lindsey JT: A retrospective analysis of 48 infected sternal wound closures: delayed closure decreases wound complications. Plast Reconstr Surg. 2002, 109: 1882-1885. 10.1097/00006534-200205000-00015. discussion 1886-1887CrossRefPubMed
21.
go back to reference Fleck TM, Fleck M, Moidl R, Czerny M, Koller R, Giovanoli P, Hiesmayer MJ, Zimpfer D, Wolner E, Grabenwoger M: The vacuum-assisted closure system for the treatment of deep sternal wound infections after cardiac surgery. Ann Thorac Surg. 2002, 74: 1596-1600. 10.1016/S0003-4975(02)03948-6. discussion 1600CrossRefPubMed Fleck TM, Fleck M, Moidl R, Czerny M, Koller R, Giovanoli P, Hiesmayer MJ, Zimpfer D, Wolner E, Grabenwoger M: The vacuum-assisted closure system for the treatment of deep sternal wound infections after cardiac surgery. Ann Thorac Surg. 2002, 74: 1596-1600. 10.1016/S0003-4975(02)03948-6. discussion 1600CrossRefPubMed
22.
go back to reference Gustafsson R, Johnsson P, Algotsson L, Blomquist S, Ingemansson R: Vacuum-assisted closure therapy guided by C-reactive protein level in patients with deep sternal wound infection. J Thorac Cardiovasc Surg. 2002, 123: 895-900. 10.1067/mtc.2002.121306.CrossRefPubMed Gustafsson R, Johnsson P, Algotsson L, Blomquist S, Ingemansson R: Vacuum-assisted closure therapy guided by C-reactive protein level in patients with deep sternal wound infection. J Thorac Cardiovasc Surg. 2002, 123: 895-900. 10.1067/mtc.2002.121306.CrossRefPubMed
23.
go back to reference Domkowski PW, Smith ML, Gonyon DL, Drye C, Wooten MK, Levin LS, Wolfe WG: Evaluation of vacuum-assisted closure in the treatment of poststernotomy mediastinitis. J Thorac Cardiovasc Surg. 2003, 126: 386-390. 10.1016/S0022-5223(03)00352-0.CrossRefPubMed Domkowski PW, Smith ML, Gonyon DL, Drye C, Wooten MK, Levin LS, Wolfe WG: Evaluation of vacuum-assisted closure in the treatment of poststernotomy mediastinitis. J Thorac Cardiovasc Surg. 2003, 126: 386-390. 10.1016/S0022-5223(03)00352-0.CrossRefPubMed
24.
go back to reference Immer FF, Durrer M, Muhlemann KS, Erni D, Gahl B, Carrel TP: Deep sternal wound infection after cardiac surgery: modality of treatment and outcome. Ann Thorac Surg. 2005, 80: 957-961. 10.1016/j.athoracsur.2005.03.035.CrossRefPubMed Immer FF, Durrer M, Muhlemann KS, Erni D, Gahl B, Carrel TP: Deep sternal wound infection after cardiac surgery: modality of treatment and outcome. Ann Thorac Surg. 2005, 80: 957-961. 10.1016/j.athoracsur.2005.03.035.CrossRefPubMed
25.
go back to reference Cowan KN, Teague L, Sue SC, Mahoney JL: Vacuum-assisted wound closure of deep sternal infections in high-risk patients after cardiac surgery. Ann Thorac Surg. 2005, 80: 2205-2212. 10.1016/j.athoracsur.2005.04.005.CrossRefPubMed Cowan KN, Teague L, Sue SC, Mahoney JL: Vacuum-assisted wound closure of deep sternal infections in high-risk patients after cardiac surgery. Ann Thorac Surg. 2005, 80: 2205-2212. 10.1016/j.athoracsur.2005.04.005.CrossRefPubMed
Metadata
Title
Secondary omental and pectoralis major double flap reconstruction following aggressive sternectomy for deep sternal wound infections after cardiac surgery
Authors
Toshiro Kobayashi
Akihito Mikamo
Hiroshi Kurazumi
Ryo Suzuki
Bungo Shirasawa
Kimikazu Hamano
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2011
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/1749-8090-6-56

Other articles of this Issue 1/2011

Journal of Cardiothoracic Surgery 1/2011 Go to the issue