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Published in: Radiation Oncology 1/2008

Open Access 01-12-2008 | Research

Motion compensation with a scanned ion beam: a technical feasibility study

Authors: Sven Oliver Grözinger, Christoph Bert, Thomas Haberer, Gerhard Kraft, Eike Rietzel

Published in: Radiation Oncology | Issue 1/2008

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Abstract

Background

Intrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target motion by tracking with the treatment beam.

Methods

Lateral motion components were compensated directly with the beam scanning system by adapting nominal beam positions according to the target motion. Longitudinal motion compensation to mitigate motion induced range changes was performed with a dedicated wedge system that adjusts effective particle energies at isocenter.

Results

Lateral compensation performance was better than 1% for a homogeneous dose distribution when comparing irradiations of a stationary radiographic film and a moving film using motion compensation. The accuracy of longitudinal range compensation was well below 1 mm.

Conclusion

Motion compensation with scanned particle beams is technically feasible with high precision.
Appendix
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Literature
1.
go back to reference ICRU: Report 50. Bethesda, Md, USA, International Commission on Radiation Units and Measurements; 1993. ICRU: Report 50. Bethesda, Md, USA, International Commission on Radiation Units and Measurements; 1993.
2.
go back to reference ICRU: Report 62. Bethesda, Md, USA, International Commission on Radiation Units and Measurements; 1999. ICRU: Report 62. Bethesda, Md, USA, International Commission on Radiation Units and Measurements; 1999.
3.
go back to reference Phillips MH, Pedroni E, Blattmann H, Boehringer T, Coray A, Scheib S: Effects of respiratory motion on dose uniformity with a charged particle scanning method. Phys Med Biol 1992, 37: 223-233. 10.1088/0031-9155/37/1/016CrossRefPubMed Phillips MH, Pedroni E, Blattmann H, Boehringer T, Coray A, Scheib S: Effects of respiratory motion on dose uniformity with a charged particle scanning method. Phys Med Biol 1992, 37: 223-233. 10.1088/0031-9155/37/1/016CrossRefPubMed
4.
go back to reference Grozinger SO, Rietzel E, Li Q, Bert C, Haberer T, Kraft G: Simulations to design an online motion compensation system for scanned particle beams. Phys Med Biol 2006, 51: 3517-3531. 10.1088/0031-9155/51/14/016CrossRefPubMed Grozinger SO, Rietzel E, Li Q, Bert C, Haberer T, Kraft G: Simulations to design an online motion compensation system for scanned particle beams. Phys Med Biol 2006, 51: 3517-3531. 10.1088/0031-9155/51/14/016CrossRefPubMed
5.
go back to reference Bert C, Grözinger SO, Rietzel E: Quantification of interplay effects of scanned particle beams and moving targets. Phys Med Biol 2008, 53: 2253-2265. 10.1088/0031-9155/53/9/003CrossRefPubMed Bert C, Grözinger SO, Rietzel E: Quantification of interplay effects of scanned particle beams and moving targets. Phys Med Biol 2008, 53: 2253-2265. 10.1088/0031-9155/53/9/003CrossRefPubMed
6.
go back to reference Kraft G: Tumor Therapy with Heavy Charged Particles. Prog Part Nucl Phys 2000, 45: 473. 10.1016/S0146-6410(00)00112-5CrossRef Kraft G: Tumor Therapy with Heavy Charged Particles. Prog Part Nucl Phys 2000, 45: 473. 10.1016/S0146-6410(00)00112-5CrossRef
7.
go back to reference Debus J, Haberer T, Schulz-Ertner D, Jakel O, Wenz F, Enghardt W, Schlegel W, Kraft G, Wannenmacher M: Carbon ion irradiation of skull base tumors at GSI. First clinical results and future perspectives. Strahlenther Onkol 2000, 176: 211-216. 10.1007/s000660050002CrossRefPubMed Debus J, Haberer T, Schulz-Ertner D, Jakel O, Wenz F, Enghardt W, Schlegel W, Kraft G, Wannenmacher M: Carbon ion irradiation of skull base tumors at GSI. First clinical results and future perspectives. Strahlenther Onkol 2000, 176: 211-216. 10.1007/s000660050002CrossRefPubMed
8.
go back to reference Schulz-Ertner D, Jakel O, Schlegel W: Radiation therapy with charged particles. Semin Radiat Oncol 2006, 16: 249-259. 10.1016/j.semradonc.2006.04.008CrossRefPubMed Schulz-Ertner D, Jakel O, Schlegel W: Radiation therapy with charged particles. Semin Radiat Oncol 2006, 16: 249-259. 10.1016/j.semradonc.2006.04.008CrossRefPubMed
9.
go back to reference Schulz-Ertner D, Tsujii H: Particle Radiation Therapy Using Proton and Heavier Ion Beams. J Clin Oncol 2007, 25: 953-964. 10.1200/JCO.2006.09.7816CrossRefPubMed Schulz-Ertner D, Tsujii H: Particle Radiation Therapy Using Proton and Heavier Ion Beams. J Clin Oncol 2007, 25: 953-964. 10.1200/JCO.2006.09.7816CrossRefPubMed
10.
go back to reference Haberer T, Becher W, Schardt D, Kraft G: Magnetic scanning system for heavy ion therapy. Nucl Instrum Meth A 1993, 330: 296-305. 10.1016/0168-9002(93)91335-KCrossRef Haberer T, Becher W, Schardt D, Kraft G: Magnetic scanning system for heavy ion therapy. Nucl Instrum Meth A 1993, 330: 296-305. 10.1016/0168-9002(93)91335-KCrossRef
11.
go back to reference Krämer M, Scholz M: Treatment planning for heavy-ion radiotherapy: calculation and optimization of biologically effective dose. Phys Med Biol 2000, 45: 3319-3330. 10.1088/0031-9155/45/11/314CrossRefPubMed Krämer M, Scholz M: Treatment planning for heavy-ion radiotherapy: calculation and optimization of biologically effective dose. Phys Med Biol 2000, 45: 3319-3330. 10.1088/0031-9155/45/11/314CrossRefPubMed
12.
go back to reference Krämer M, Jäkel O, Haberer T, Kraft G, Schardt D, Weber U: Treatment planning for heavy-ion radiotherapy: physical beam model and dose optimization. Phys Med Biol 2000, 45: 3299-3317. 10.1088/0031-9155/45/11/313CrossRefPubMed Krämer M, Jäkel O, Haberer T, Kraft G, Schardt D, Weber U: Treatment planning for heavy-ion radiotherapy: physical beam model and dose optimization. Phys Med Biol 2000, 45: 3299-3317. 10.1088/0031-9155/45/11/313CrossRefPubMed
13.
go back to reference Krämer M, Scholz M: Rapid calculation of biological effects in ion radiotherapy. Phys Med Biol 2006, 51: 1959-1970. 10.1088/0031-9155/51/8/001CrossRefPubMed Krämer M, Scholz M: Rapid calculation of biological effects in ion radiotherapy. Phys Med Biol 2006, 51: 1959-1970. 10.1088/0031-9155/51/8/001CrossRefPubMed
14.
go back to reference Scholz M, Kraft G: Calculation of heavy ion inactivation probabilities based on track structure, x ray sensitivity and target size. Radiat Prot Dosim 1994, 52: 29-33. Scholz M, Kraft G: Calculation of heavy ion inactivation probabilities based on track structure, x ray sensitivity and target size. Radiat Prot Dosim 1994, 52: 29-33.
15.
go back to reference Scholz M, Kellerer AM, Kraft-Weyrather W, Kraft G: Computation of cell survival in heavy ion beams for therapy. The model and its approximation. Radiat Environ Biophys 1997, 36: 59-66. 10.1007/s004110050055CrossRefPubMed Scholz M, Kellerer AM, Kraft-Weyrather W, Kraft G: Computation of cell survival in heavy ion beams for therapy. The model and its approximation. Radiat Environ Biophys 1997, 36: 59-66. 10.1007/s004110050055CrossRefPubMed
16.
go back to reference Jäkel O, Krämer M, Karger CP, Debus J: Treatment planning for heavy ion radiotherapy: clinical implementation and application. Phys Med Biol 2001, 46: 1101-1116. 10.1088/0031-9155/46/4/314CrossRefPubMed Jäkel O, Krämer M, Karger CP, Debus J: Treatment planning for heavy ion radiotherapy: clinical implementation and application. Phys Med Biol 2001, 46: 1101-1116. 10.1088/0031-9155/46/4/314CrossRefPubMed
17.
go back to reference Schulz-Ertner D, Nikoghosyan A, Thilmann C, Haberer T, Jäkel O, Karger C, Kraft G, Wannenmacher M, Debus J: Results of carbon ion radiotherapy in 152 patients. Int J Radiat Oncol 2004, 58: 631-640. 10.1016/j.ijrobp.2003.09.041CrossRef Schulz-Ertner D, Nikoghosyan A, Thilmann C, Haberer T, Jäkel O, Karger C, Kraft G, Wannenmacher M, Debus J: Results of carbon ion radiotherapy in 152 patients. Int J Radiat Oncol 2004, 58: 631-640. 10.1016/j.ijrobp.2003.09.041CrossRef
18.
go back to reference Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jakel O, Karger CP, Edler L, Debus J: Carbon ion radiotherapy of skull base chondrosarcomas. Int J Radiat Oncol Biol Phys 2007, 67: 171-177.CrossRefPubMed Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jakel O, Karger CP, Edler L, Debus J: Carbon ion radiotherapy of skull base chondrosarcomas. Int J Radiat Oncol Biol Phys 2007, 67: 171-177.CrossRefPubMed
19.
go back to reference Nikoghosyan A, Schulz-Ertner D, Didinger B, Jakel O, Zuna I, Hoss A, Wannenmacher M, Debus J: Evaluation of therapeutic potential of heavy ion therapy for patients with locally advanced prostate cancer. Int J Radiat Oncol Biol Phys 2004, 58: 89-97. 10.1016/S0360-3016(03)01439-1CrossRefPubMed Nikoghosyan A, Schulz-Ertner D, Didinger B, Jakel O, Zuna I, Hoss A, Wannenmacher M, Debus J: Evaluation of therapeutic potential of heavy ion therapy for patients with locally advanced prostate cancer. Int J Radiat Oncol Biol Phys 2004, 58: 89-97. 10.1016/S0360-3016(03)01439-1CrossRefPubMed
20.
go back to reference Li Q, Grözinger SO, Haberer T, Rietzel E, Kraft G: Online compensation of target motion with scanned particle beams: simulation environment. Phys Med Biol 2004, 49: 3029-3046. 10.1088/0031-9155/49/14/001CrossRefPubMed Li Q, Grözinger SO, Haberer T, Rietzel E, Kraft G: Online compensation of target motion with scanned particle beams: simulation environment. Phys Med Biol 2004, 49: 3029-3046. 10.1088/0031-9155/49/14/001CrossRefPubMed
21.
go back to reference Weber U, Becher W, Kraft G: Depth scanning for a conformal ion beam treatment of deep seated tumours. Phys Med Biol 2000, 45: 3627-3641. 10.1088/0031-9155/45/12/309CrossRefPubMed Weber U, Becher W, Kraft G: Depth scanning for a conformal ion beam treatment of deep seated tumours. Phys Med Biol 2000, 45: 3627-3641. 10.1088/0031-9155/45/12/309CrossRefPubMed
22.
go back to reference Sihver L, Schardt D, Kanai T: Depth-dose distributions of high-energy carbon, oxygen and neon beams in water. Jpn J Med Phys 1998, 18: 1-21. Sihver L, Schardt D, Kanai T: Depth-dose distributions of high-energy carbon, oxygen and neon beams in water. Jpn J Med Phys 1998, 18: 1-21.
23.
go back to reference Bathelt B: Filmdosimetrie in der Schwerionen-Tumortherapie: 3-dimensionale Dosisverifikation in gemischten Teilchenstrahlfeldern. Gesamthochschule Kassel; 2000. Bathelt B: Filmdosimetrie in der Schwerionen-Tumortherapie: 3-dimensionale Dosisverifikation in gemischten Teilchenstrahlfeldern. Gesamthochschule Kassel; 2000.
24.
go back to reference Spielberger B, Scholz M, Krämer M, Kraft G: Experimental investigations of the response of films to heavy-ion irradiation. Phys Med Biol 2001, 46: 2889-2897. 10.1088/0031-9155/46/11/309CrossRefPubMed Spielberger B, Scholz M, Krämer M, Kraft G: Experimental investigations of the response of films to heavy-ion irradiation. Phys Med Biol 2001, 46: 2889-2897. 10.1088/0031-9155/46/11/309CrossRefPubMed
25.
go back to reference Schardt D, Stelzer H, Junk H, Arndt U: Bragg curve measurements with ionisation chambers. Grundinger, U. 336. Darmstadt, Gesellschaft für Schwerionenforschung mbH. GSI Scientific Report 1992 1993. Schardt D, Stelzer H, Junk H, Arndt U: Bragg curve measurements with ionisation chambers. Grundinger, U. 336. Darmstadt, Gesellschaft für Schwerionenforschung mbH. GSI Scientific Report 1992 1993.
26.
go back to reference Rietzel E, Schardt D, Haberer T: Range accuracy in carbon ion treatment planning based on CT-calibration with real tissue samples. Radiat Oncol 2007, 2: 14. 10.1186/1748-717X-2-14PubMedCentralCrossRefPubMed Rietzel E, Schardt D, Haberer T: Range accuracy in carbon ion treatment planning based on CT-calibration with real tissue samples. Radiat Oncol 2007, 2: 14. 10.1186/1748-717X-2-14PubMedCentralCrossRefPubMed
27.
go back to reference Schardt D, Schall I, Geissel H, Irnich H, Kraft G, Magel A, Mohar MF, Munzenberg G, Nickel F, Scheidenberger C, Schwab W, Sihver L: Nuclear fragmentation of high-energy heavy-ion beams in water. Adv Space Res 1996, 17: 87-94. 10.1016/0273-1177(95)00516-HCrossRefPubMed Schardt D, Schall I, Geissel H, Irnich H, Kraft G, Magel A, Mohar MF, Munzenberg G, Nickel F, Scheidenberger C, Schwab W, Sihver L: Nuclear fragmentation of high-energy heavy-ion beams in water. Adv Space Res 1996, 17: 87-94. 10.1016/0273-1177(95)00516-HCrossRefPubMed
28.
go back to reference Schall I, Schardt D, Geissel H, Irnich H, Kankeleit E, Kraft G, Magel A, Mohar MF, Mnnzenberg G, Nickel F, Scheidenberger C, Schwab W: Charge-changing nuclear reactions of relativistic light-ion beams (5 <= Z <= 10) passing through thick absorbers. Nucl Instrum Meth B 1996, 117: 221-234. 10.1016/0168-583X(96)00325-4CrossRef Schall I, Schardt D, Geissel H, Irnich H, Kankeleit E, Kraft G, Magel A, Mohar MF, Mnnzenberg G, Nickel F, Scheidenberger C, Schwab W: Charge-changing nuclear reactions of relativistic light-ion beams (5 <= Z <= 10) passing through thick absorbers. Nucl Instrum Meth B 1996, 117: 221-234. 10.1016/0168-583X(96)00325-4CrossRef
29.
go back to reference Gunzert-Marx K, Iwase H, Schardt D, Simon RS: Secondary beam fragments produced by 200 MeVu(-1) C-12 ions in water and their dose contributions in carbon ion radiotherapy. New Journal of Physics 2008., 10: Gunzert-Marx K, Iwase H, Schardt D, Simon RS: Secondary beam fragments produced by 200 MeVu(-1) C-12 ions in water and their dose contributions in carbon ion radiotherapy. New Journal of Physics 2008., 10:
30.
go back to reference Ford EC, Mageras GS, Yorke E, Ling CC: Respiration-correlated spiral CT: A method of measuring respiratory-induced anatomic motion for radiation treatment planning. Med Phys 2003, 30: 88-97. 10.1118/1.1531177CrossRefPubMed Ford EC, Mageras GS, Yorke E, Ling CC: Respiration-correlated spiral CT: A method of measuring respiratory-induced anatomic motion for radiation treatment planning. Med Phys 2003, 30: 88-97. 10.1118/1.1531177CrossRefPubMed
31.
go back to reference Vedam SS, Keall PJ, Kini VR, Mostafavi H, Shukla HP, Mohan R: Acquiring a four-dimensional computed tomography dataset using an external respiratory signal. Phys Med Biol 2003, 48: 45-62. 10.1088/0031-9155/48/1/304CrossRefPubMed Vedam SS, Keall PJ, Kini VR, Mostafavi H, Shukla HP, Mohan R: Acquiring a four-dimensional computed tomography dataset using an external respiratory signal. Phys Med Biol 2003, 48: 45-62. 10.1088/0031-9155/48/1/304CrossRefPubMed
32.
go back to reference Rietzel E, Pan T, Chen GTY: Four-dimensional computed tomography: Image formation and clinical protocol. Med Phys 2005, 32: 874-889. 10.1118/1.1869852CrossRefPubMed Rietzel E, Pan T, Chen GTY: Four-dimensional computed tomography: Image formation and clinical protocol. Med Phys 2005, 32: 874-889. 10.1118/1.1869852CrossRefPubMed
33.
go back to reference Shirato H, Shimizu S, Kunieda T, Kitamura K, Kagei K, Nishioka T, Hashimoto S, Fujita K, Aoyama H: Physical aspects of a real-time tumor-tracking system for gated radiotherapy. Int J Radiat Oncol 2000, 48: 1187-1195. 10.1016/S0360-3016(00)00748-3CrossRef Shirato H, Shimizu S, Kunieda T, Kitamura K, Kagei K, Nishioka T, Hashimoto S, Fujita K, Aoyama H: Physical aspects of a real-time tumor-tracking system for gated radiotherapy. Int J Radiat Oncol 2000, 48: 1187-1195. 10.1016/S0360-3016(00)00748-3CrossRef
34.
go back to reference Berbeco RI, Jiang SB, Sharp GC, Chen GTY, Mostafavi H, Shirato H: Integrated radiotherapy imaging system (IRIS): design considerations of tumour tracking with linac gantry-mounted diagnostic x-ray systems with flat-panel detectors. Phys Med Biol 2004, 49: 243-255. 10.1088/0031-9155/49/2/005CrossRefPubMed Berbeco RI, Jiang SB, Sharp GC, Chen GTY, Mostafavi H, Shirato H: Integrated radiotherapy imaging system (IRIS): design considerations of tumour tracking with linac gantry-mounted diagnostic x-ray systems with flat-panel detectors. Phys Med Biol 2004, 49: 243-255. 10.1088/0031-9155/49/2/005CrossRefPubMed
35.
go back to reference Shirato H, Harada T, Harabayashi T, Hida K, Endo H, Kitamura K, Onimaru R, Yamazaki K, Kurauchi N, Shimizu T, Shinohara N, Matsushita M, aka-Akita H, Miyasaka K: Feasibility of insertion/implantation of 2.0-mm-diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy. Int J Radiat Oncol Biol Phys 2003, 56: 240-247.CrossRefPubMed Shirato H, Harada T, Harabayashi T, Hida K, Endo H, Kitamura K, Onimaru R, Yamazaki K, Kurauchi N, Shimizu T, Shinohara N, Matsushita M, aka-Akita H, Miyasaka K: Feasibility of insertion/implantation of 2.0-mm-diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy. Int J Radiat Oncol Biol Phys 2003, 56: 240-247.CrossRefPubMed
36.
go back to reference Shimizu S, Shirato H, Kitamura K, Shinohara N, Harabayashi T, Tsukamoto T, Koyanagi T, Miyasaka K: Use of an implanted marker and real-time tracking of the marker for the positioning of prostate and bladder cancers. Int J Radiat Oncol 2000, 48: 1591-1597. 10.1016/S0360-3016(00)00809-9CrossRef Shimizu S, Shirato H, Kitamura K, Shinohara N, Harabayashi T, Tsukamoto T, Koyanagi T, Miyasaka K: Use of an implanted marker and real-time tracking of the marker for the positioning of prostate and bladder cancers. Int J Radiat Oncol 2000, 48: 1591-1597. 10.1016/S0360-3016(00)00809-9CrossRef
37.
go back to reference Schweikard A, Shiomi H, Adler J: Respiration tracking in radiosurgery. Med Phys 2004, 31: 2738-2741. 10.1118/1.1774132CrossRefPubMed Schweikard A, Shiomi H, Adler J: Respiration tracking in radiosurgery. Med Phys 2004, 31: 2738-2741. 10.1118/1.1774132CrossRefPubMed
38.
go back to reference Rietzel E, Rosenthal SJ, Gierga DP, Willet CG, Chen GT: Moving targets: detection and tracking of internal organ motion for treatment planning and patient set-up. Radiother Oncol 2004,73(Suppl 2):S68-S72. 10.1016/S0167-8140(04)80018-5CrossRefPubMed Rietzel E, Rosenthal SJ, Gierga DP, Willet CG, Chen GT: Moving targets: detection and tracking of internal organ motion for treatment planning and patient set-up. Radiother Oncol 2004,73(Suppl 2):S68-S72. 10.1016/S0167-8140(04)80018-5CrossRefPubMed
39.
go back to reference Baroni G, Ferrigno G, Pedotti A: Implementation and application of real-time motion analysis based on passive markers. Med Biol Eng Comput 1998, 36: 693-703. 10.1007/BF02518871CrossRefPubMed Baroni G, Ferrigno G, Pedotti A: Implementation and application of real-time motion analysis based on passive markers. Med Biol Eng Comput 1998, 36: 693-703. 10.1007/BF02518871CrossRefPubMed
40.
go back to reference Kubo HD, Len PM, Minohara S, Mostafavi H: Breathing-synchronized radiotherapy program at the University of California Davis Cancer Center. Med Phys 2000, 27: 346-353. 10.1118/1.598837CrossRefPubMed Kubo HD, Len PM, Minohara S, Mostafavi H: Breathing-synchronized radiotherapy program at the University of California Davis Cancer Center. Med Phys 2000, 27: 346-353. 10.1118/1.598837CrossRefPubMed
41.
go back to reference Ford EC, Mageras GS, Yorke E, Rosenzweig KE, Wagman R, Ling CC: Evaluation of respiratory movement during gated radiotherapy using film and electronic portal imaging. Int J Radiat Oncol 2002, 52: 522-531. 10.1016/S0360-3016(01)02681-5CrossRef Ford EC, Mageras GS, Yorke E, Rosenzweig KE, Wagman R, Ling CC: Evaluation of respiratory movement during gated radiotherapy using film and electronic portal imaging. Int J Radiat Oncol 2002, 52: 522-531. 10.1016/S0360-3016(01)02681-5CrossRef
42.
go back to reference Smith N, Meir I, Hale G, Howe R, Johnson L, Edwards P, Hawkes D, Bidmead M, Landau D: Real-time 3D surface imaging for patient positioning in radiotherapy. Int J Radiat Oncol 2003, 57: S187.CrossRef Smith N, Meir I, Hale G, Howe R, Johnson L, Edwards P, Hawkes D, Bidmead M, Landau D: Real-time 3D surface imaging for patient positioning in radiotherapy. Int J Radiat Oncol 2003, 57: S187.CrossRef
43.
go back to reference Kuechler S, Hoinkis C, Thierfelder C, Becker B, Zahn P, Geyer P, Lehmann D: Respiratory motion – first investigations on the optimization of gating parameters. Int J Radiat Oncol 2004, 60: 579. 10.1016/j.ijrobp.2004.07.570CrossRef Kuechler S, Hoinkis C, Thierfelder C, Becker B, Zahn P, Geyer P, Lehmann D: Respiratory motion – first investigations on the optimization of gating parameters. Int J Radiat Oncol 2004, 60: 579. 10.1016/j.ijrobp.2004.07.570CrossRef
44.
go back to reference Bert C, Metheany KG, Doppke K, Chen GT: A phantom evaluation of a stereo-vision surface imaging system for radiotherapy patient setup. Med Phys 2005, 32: 2753-2762. 10.1118/1.1984263CrossRefPubMed Bert C, Metheany KG, Doppke K, Chen GT: A phantom evaluation of a stereo-vision surface imaging system for radiotherapy patient setup. Med Phys 2005, 32: 2753-2762. 10.1118/1.1984263CrossRefPubMed
45.
go back to reference Li XA, Stepaniak C, Gore E: Technical and dosimetric aspects of respiratory gating using a pressure-sensor motion monitoring system. Med Phys 2006, 33: 145-154. 10.1118/1.2147743CrossRefPubMed Li XA, Stepaniak C, Gore E: Technical and dosimetric aspects of respiratory gating using a pressure-sensor motion monitoring system. Med Phys 2006, 33: 145-154. 10.1118/1.2147743CrossRefPubMed
46.
go back to reference Willoughby TR, Forbes AR, Buchholz D, Langen KM, Wagner TH, Zeidan OA, Kupelian PA, Meeks SL: Evaluation of an infrared camera and X-ray system using implanted fiducials in patients with lung tumors for gated radiation therapy. Int J Radiat Oncol Biol Phys 2006, 66: 568-575.CrossRefPubMed Willoughby TR, Forbes AR, Buchholz D, Langen KM, Wagner TH, Zeidan OA, Kupelian PA, Meeks SL: Evaluation of an infrared camera and X-ray system using implanted fiducials in patients with lung tumors for gated radiation therapy. Int J Radiat Oncol Biol Phys 2006, 66: 568-575.CrossRefPubMed
47.
go back to reference Rietzel E, Chen GTY, Choi NC, Willet CG: Four-dimensional image-based treatment planning: Target volume segmentation and dose calculation in the presence of respiratory motion. Int J Radiat Oncol 2005, 61: 1535-1550. 10.1016/j.ijrobp.2004.11.037CrossRef Rietzel E, Chen GTY, Choi NC, Willet CG: Four-dimensional image-based treatment planning: Target volume segmentation and dose calculation in the presence of respiratory motion. Int J Radiat Oncol 2005, 61: 1535-1550. 10.1016/j.ijrobp.2004.11.037CrossRef
48.
go back to reference Bert C, Rietzel E: 4D treatment planning for scanned ion beams. Radiat Oncol 2007., 2: Bert C, Rietzel E: 4D treatment planning for scanned ion beams. Radiat Oncol 2007., 2:
Metadata
Title
Motion compensation with a scanned ion beam: a technical feasibility study
Authors
Sven Oliver Grözinger
Christoph Bert
Thomas Haberer
Gerhard Kraft
Eike Rietzel
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2008
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/1748-717X-3-34

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