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Open Access 01-12-2008 | Study protocol

FDG-PET/CT imaging for staging and radiotherapy treatment planning of head and neck carcinoma

Authors: Letizia Deantonio, Debora Beldì, Giuseppina Gambaro, Gianfranco Loi, Marco Brambilla, Eugenio Inglese, Marco Krengli

Published in: Radiation Oncology | Issue 1/2008

Abstract

Background

Positron emission tomography (PET) has a potential improvement for staging and radiation treatment planning of various tumor sites. We analyzed the use of ¹⁸F-fluorodeoxyglucose (FDG)-PET/computed tomography (CT) images for staging and target volume delineation of patients with head and neck carcinoma candidates for radiotherapy.

Methods

Twenty-two patients candidates for primary radiotherapy, who did not receive any curative surgery, underwent both CT and PET/CT simulation. Gross Tumor Volume (GTV) was contoured on CT (CT-GTV), PET (PET-GTV), and PET/CT images (PET/CT-GTV). The resulting volumes were analyzed and compared.

Results

Based on PET/CT, changes in TNM categories and clinical stage occurred in 5/22 cases (22%). The difference between CT-GTV and PET-GTV was not statistically significant (p = 0.2) whereas the difference between the composite volume (PET/CT-GTV) and CT-GTV was statistically significant (p < 0.0001).

Conclusion

PET/CT fusion images could have a potential impact on both tumor staging and treatment planning.

Available only for authorised users

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Title: FDG-PET/CT imaging for staging and radiotherapy treatment planning of head and neck carcinoma
Authors: Letizia Deantonio
Debora Beldì
Giuseppina Gambaro
Gianfranco Loi
Marco Brambilla
Eugenio Inglese
Marco Krengli
Publication date: 01-12-2008
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2008
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-3-29

Keynote webinar | Spotlight on medication adherence

Springer Medicine

FDG-PET/CT imaging for staging and radiotherapy treatment planning of head and neck carcinoma

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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