Published in:
Open Access
01-12-2011 | Editorial
Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
Authors:
Jörg Handschel, Ulrich Meyer
Published in:
Head & Face Medicine
|
Issue 1/2011
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Abstract
Osteonecrosis after craniofacial radiation (ORN), osteomyelitis and bisphosphonates related necrosis of the jaw (BRONJ) are the predominant bone diseases in Cranio- and Maxillofacial surgery. Although various hypothesis for the pathophysiological mechanisms including infection, altered vascularisation or remodelling exist, the treatment is still a challenge for clinicians. As the classical pharmacological or surgical treatment protocols have only limited success, stem cells might be a promising treatment option, indicated by recently published data.