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Published in: Head & Face Medicine 1/2011

Open Access 01-12-2011 | Editorial

Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?

Authors: Jörg Handschel, Ulrich Meyer

Published in: Head & Face Medicine | Issue 1/2011

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Abstract

Osteonecrosis after craniofacial radiation (ORN), osteomyelitis and bisphosphonates related necrosis of the jaw (BRONJ) are the predominant bone diseases in Cranio- and Maxillofacial surgery. Although various hypothesis for the pathophysiological mechanisms including infection, altered vascularisation or remodelling exist, the treatment is still a challenge for clinicians. As the classical pharmacological or surgical treatment protocols have only limited success, stem cells might be a promising treatment option, indicated by recently published data.
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Metadata
Title
Infection, vascularization, remodelling - are stem cells the answers for bone diseases of the jaws?
Authors
Jörg Handschel
Ulrich Meyer
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Head & Face Medicine / Issue 1/2011
Electronic ISSN: 1746-160X
DOI
https://doi.org/10.1186/1746-160X-7-5

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