Skip to main content
Top
Published in: Diagnostic Pathology 1/2009

Open Access 01-12-2009 | Research

Histopathological study of lesions of the caruncle: a 15-year single center review

Authors: Helena P Solari, M Palis Ventura, Maria Eugenia Orellana, Gustavo A Novais, Devinder P Cheema, Miguel N Burnier Jr

Published in: Diagnostic Pathology | Issue 1/2009

Login to get access

Abstract

Introduction

The caruncle is a modified cutaneous tissue located at the inner canthus that contains hair follicles, accessory lacrimal glands, sweat glands and sebaceous glands. These different types of tissues can give rise to a wide variety of lesions that make the clinical diagnosis difficult. The aim of the study was to investigate the most common types of caruncle lesions and the clinical and pathological correlation.

Methods

Retrospective, observational case series. Records of caruncle lesions examined at the Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Canada, between 1993 and 2008 were analyzed, comparing the clinical and histopathological findings.

Results

A total of 42 lesions from 42 patients were analyzed. Twenty-six (61.90%) of the patients were women and 16 (38.10%) were men and the age range from 20 to 84. The main diagnoses were: 16 epithelial lesions (38.09%), 14 inflammatory lesions (31.70%), 10 melanocytic lesions (21,95%), 2 lymphoid lesions (4.87%). From the 28 cases that had a preoperative clinical hypothesis only 17 presented a histopathological confirmation of the diagnosis (60.71%).

Conclusion

The most common caruncle lesions were epithelial tumors followed by chronic inflammation and melanocytic lesions. Although most of the lesions were benign, there was a great number of misdiagnose based on the clinical suspicious.
Appendix
Available only for authorised users
Literature
1.
go back to reference Spencer WH, Folberg R: Conjunctiva. Ophthalmic Pathology. An Atlas and Textbook. 1996, WB Saunders. Philadelphia: Spencer WH, I: 125-155. 4 Spencer WH, Folberg R: Conjunctiva. Ophthalmic Pathology. An Atlas and Textbook. 1996, WB Saunders. Philadelphia: Spencer WH, I: 125-155. 4
2.
go back to reference Kaeser P, Uffer S, Zografos L, Hamédani M: Tumors of the caruncle: a clinicopathologic correlation. Am J Ophthalmol. 2006, 142: 448-455. 10.1016/j.ajo.2006.04.035.CrossRefPubMed Kaeser P, Uffer S, Zografos L, Hamédani M: Tumors of the caruncle: a clinicopathologic correlation. Am J Ophthalmol. 2006, 142: 448-455. 10.1016/j.ajo.2006.04.035.CrossRefPubMed
3.
go back to reference Luthra CL, Doxanas MT, Green WR: Lesions of the caruncle: a clinicohistopathologic study. Surv Ophthalmol. 1978, 23: 183-195. 10.1016/0039-6257(78)90155-8.CrossRefPubMed Luthra CL, Doxanas MT, Green WR: Lesions of the caruncle: a clinicohistopathologic study. Surv Ophthalmol. 1978, 23: 183-195. 10.1016/0039-6257(78)90155-8.CrossRefPubMed
4.
go back to reference Kiratli H, Kocabeyoglu S, Saglam A, Soylemezogh F: Langerhans cell histiocytosis of the caruncle. Clin and Experim Ophthalmol. 2007, 35: 661-663. 10.1111/j.1442-9071.2007.01567.x.CrossRef Kiratli H, Kocabeyoglu S, Saglam A, Soylemezogh F: Langerhans cell histiocytosis of the caruncle. Clin and Experim Ophthalmol. 2007, 35: 661-663. 10.1111/j.1442-9071.2007.01567.x.CrossRef
5.
go back to reference Shields CL, Shields JA, White D, Augsburger JJ: Types and frequency of lesions of the caruncle. Am J Ophthalmol. 1986, 102: 771-778.CrossRefPubMed Shields CL, Shields JA, White D, Augsburger JJ: Types and frequency of lesions of the caruncle. Am J Ophthalmol. 1986, 102: 771-778.CrossRefPubMed
6.
go back to reference Santos A, Gomez-Leal A: Lesion of the lacrimal caruncle: clinicopathologic features. Ophthalmology. 1991, 101: 943-949.CrossRef Santos A, Gomez-Leal A: Lesion of the lacrimal caruncle: clinicopathologic features. Ophthalmology. 1991, 101: 943-949.CrossRef
7.
go back to reference Nelson JD, Cameron JD: The conjunctiva. Cornea. Fundamentals of Cornea and External Disease. Edited by: Krachmer JH, Mannis MJ, Holland EJ. 2004, Elsevier Mosby. St. Louis, I: 37-44. 2 Nelson JD, Cameron JD: The conjunctiva. Cornea. Fundamentals of Cornea and External Disease. Edited by: Krachmer JH, Mannis MJ, Holland EJ. 2004, Elsevier Mosby. St. Louis, I: 37-44. 2
8.
go back to reference Bron AJ, Tripathi RC, Tripathi BJ: Wolff's anatomy of the eye and orbit. 1997, Chapman and Hall Medical. Spain, 70-1. 18 Bron AJ, Tripathi RC, Tripathi BJ: Wolff's anatomy of the eye and orbit. 1997, Chapman and Hall Medical. Spain, 70-1. 18
9.
go back to reference Song A, Carter KD, Syed NA, Song J, Nerad JA: Sebaceous cell carcinoma of the ocular adnexa: clinical presentations, histopathology, and outcomes. Ophthalmic Plastic and Reconstructive Surgery. 2008, 24 (3): 194-200. 10.1097/IOP.0b013e31816d925f.CrossRefPubMed Song A, Carter KD, Syed NA, Song J, Nerad JA: Sebaceous cell carcinoma of the ocular adnexa: clinical presentations, histopathology, and outcomes. Ophthalmic Plastic and Reconstructive Surgery. 2008, 24 (3): 194-200. 10.1097/IOP.0b013e31816d925f.CrossRefPubMed
10.
go back to reference Filho JP, Vianna RNG, Coutinho AM, Arthurs B, Burnier MN: Oncocytoma of the caruncle: a clinicopathologic case report. Invest Ophthalmol Vis Sci. 2004, 25 (5-6): 321-323. Filho JP, Vianna RNG, Coutinho AM, Arthurs B, Burnier MN: Oncocytoma of the caruncle: a clinicopathologic case report. Invest Ophthalmol Vis Sci. 2004, 25 (5-6): 321-323.
11.
go back to reference Ozdal PC, Kangi S, Göka S, Callejo SA, Hucumengus S, Burnier MN: Capillary hemangioma of the caruncle. Can J Ophthalmol. 2004, 39 (5): 560-CrossRefPubMed Ozdal PC, Kangi S, Göka S, Callejo SA, Hucumengus S, Burnier MN: Capillary hemangioma of the caruncle. Can J Ophthalmol. 2004, 39 (5): 560-CrossRefPubMed
12.
go back to reference Shields CL, Shields JA, White D, Ausburger JJ: Types and frequency of lesions of the caruncle. Am J Ophthalmol. 1986, 15;102 (6): 771-8.CrossRef Shields CL, Shields JA, White D, Ausburger JJ: Types and frequency of lesions of the caruncle. Am J Ophthalmol. 1986, 15;102 (6): 771-8.CrossRef
13.
go back to reference Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc. 2008, 83 (4): 489-51. 10.4065/83.4.489.CrossRefPubMed Marur S, Forastiere AA: Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc. 2008, 83 (4): 489-51. 10.4065/83.4.489.CrossRefPubMed
14.
go back to reference Shields JA, Shield CL, Marr BP, Eagle RC: Sebaceous carcinoma of the caruncle. Cornea. 2006, 25 (7): 858-859. 10.1097/01.ico.0000224641.35977.e4.CrossRefPubMed Shields JA, Shield CL, Marr BP, Eagle RC: Sebaceous carcinoma of the caruncle. Cornea. 2006, 25 (7): 858-859. 10.1097/01.ico.0000224641.35977.e4.CrossRefPubMed
15.
go back to reference Ostergaard J, Pause JU, Heegaard S: Caruncular lesions in Denmark 1978-2002: a histopathological study with correlation to clinical referral diagnosis. Acta Ophthlmol Scand. 2006, 84: 130-6. 10.1111/j.1600-0420.2005.00543.x.CrossRef Ostergaard J, Pause JU, Heegaard S: Caruncular lesions in Denmark 1978-2002: a histopathological study with correlation to clinical referral diagnosis. Acta Ophthlmol Scand. 2006, 84: 130-6. 10.1111/j.1600-0420.2005.00543.x.CrossRef
Metadata
Title
Histopathological study of lesions of the caruncle: a 15-year single center review
Authors
Helena P Solari
M Palis Ventura
Maria Eugenia Orellana
Gustavo A Novais
Devinder P Cheema
Miguel N Burnier Jr
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2009
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-4-29

Other articles of this Issue 1/2009

Diagnostic Pathology 1/2009 Go to the issue