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Open Access 01-12-2011 | Study protocol

The Home-Based Older People's Exercise (HOPE) trial: study protocol for a randomised controlled trial

Authors: Andrew Clegg, Sally Barber, John Young, Anne Forster, Steve Iliffe

Published in: Trials | Issue 1/2011

Abstract

Background

Frailty is common in older age, and is associated with important adverse health outcomes including increased risk of disability and admission to hospital or long-term care. Exercise interventions for frail older people have the potential to reduce the risk of these adverse outcomes by increasing muscle strength and improving mobility.

Methods/Design

The Home-Based Older People's Exercise (HOPE) trial is a two arm, assessor blind pilot randomised controlled trial (RCT) to assess the effectiveness of a 12 week exercise intervention (the HOPE programme) designed to improve the mobility and functional abilities of frail older people living at home, compared with usual care. The primary outcome is the timed-up-and-go test (TUGT), measured at baseline and 14 weeks post-randomisation. Secondary outcomes include the Barthel Index of activities of daily living (ADL), EuroQol Group 5-Dimension Self-Report Questionnaire (EQ-5D) quality of life measure and the geriatric depression scale (GDS), measured at baseline and 14 weeks post-randomisation. We will record baseline frailty using the Edmonton Frail Scale (EFS), record falls and document muscle/joint pain. We will test the feasibility of collection of data to identify therapy resources required for delivery of the intervention.

Discussion

The HOPE trial will explore and evaluate a home-based exercise intervention for frail older people. Although previous RCTs have used operationalised, non-validated methods of measuring frailty, the HOPE trial is, to our knowledge, the first RCT of an exercise intervention for frail older people that includes a validated method of frailty assessment at baseline.

Trial registration

ISRCTN: ISRCTN57066881

Available only for authorised users

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Title: The Home-Based Older People's Exercise (HOPE) trial: study protocol for a randomised controlled trial
Authors: Andrew Clegg
Sally Barber
John Young
Anne Forster
Steve Iliffe
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Trials / Issue 1/2011
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/1745-6215-12-143

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The Home-Based Older People's Exercise (HOPE) trial: study protocol for a randomised controlled trial

Abstract

Background

Methods/Design

Discussion

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods/Design

Discussion

Trial registration

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