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Open Access 01-12-2006 | Review

Breaking down the barriers: fMRI applications in pain, analgesia and analgesics

Authors: David Borsook, Lino R Becerra

Published in: Molecular Pain | Issue 1/2006

Abstract

This review summarizes functional magnetic resonance imaging (fMRI) findings that have informed our current understanding of pain, analgesia and related phenomena, and discusses the potential role of fMRI in improved therapeutic approaches to pain. It is divided into 3 main sections: (1) fMRI studies of acute and chronic pain. Physiological studies of pain have found numerous regions of the brain to be involved in the interpretation of the 'pain experience'; studies in chronic pain conditions have identified a significant CNS component; and fMRI studies of surrogate models of chronic pain are also being used to further this understanding. (2) fMRI studies of endogenous pain processing including placebo, empathy, attention or cognitive modulation of pain. (3) The use of fMRI to evaluate the effects of analgesics on brain function in acute and chronic pain. fMRI has already provided novel insights into the neurobiology of pain. These insights should significantly advance therapeutic approaches to chronic pain.

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Title: Breaking down the barriers: fMRI applications in pain, analgesia and analgesics
Authors: David Borsook
Lino R Becerra
Publication date: 01-12-2006
Publisher: BioMed Central
Published in: Molecular Pain / Issue 1/2006
Electronic ISSN: 1744-8069
DOI: https://doi.org/10.1186/1744-8069-2-30

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Breaking down the barriers: fMRI applications in pain, analgesia and analgesics

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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