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Open Access 01-12-2004 | Review

Microglia and neuroinflammation: a pathological perspective

Authors: Wolfgang J Streit, Robert E Mrak, W Sue T Griffin

Published in: Journal of Neuroinflammation | Issue 1/2004

Abstract

Microglia make up the innate immune system of the central nervous system and are key cellular mediators of neuroinflammatory processes. Their role in central nervous system diseases, including infections, is discussed in terms of a participation in both acute and chronic neuroinflammatory responses. Specific reference is made also to their involvement in Alzheimer's disease where microglial cell activation is thought to be critically important in the neurodegenerative process.

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Title: Microglia and neuroinflammation: a pathological perspective
Authors: Wolfgang J Streit
Robert E Mrak
W Sue T Griffin
Publication date: 01-12-2004
Publisher: BioMed Central
Published in: Journal of Neuroinflammation / Issue 1/2004
Electronic ISSN: 1742-2094
DOI: https://doi.org/10.1186/1742-2094-1-14

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Microglia and neuroinflammation: a pathological perspective

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