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Open Access 01-12-2012 | Opinion

Spectrum of gluten-related disorders: consensus on new nomenclature and classification

Authors: Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano

Published in: BMC Medicine | Issue 1/2012

Abstract

A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10 years, key milestones have moved celiac disease from obscurity into the popular spotlight worldwide. Now we are observing another interesting phenomenon that is generating great confusion among health care professionals. The number of individuals embracing a gluten-free diet (GFD) appears much higher than the projected number of celiac disease patients, fueling a global market of gluten-free products approaching $2.5 billion (US) in global sales in 2010. This trend is supported by the notion that, along with celiac disease, other conditions related to the ingestion of gluten have emerged as health care concerns. This review will summarize our current knowledge about the three main forms of gluten reactions: allergic (wheat allergy), autoimmune (celiac disease, dermatitis herpetiformis and gluten ataxia) and possibly immune-mediated (gluten sensitivity), and also outline pathogenic, clinical and epidemiological differences and propose new nomenclature and classifications.

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1741-7015/10/13/prepub

Title: Spectrum of gluten-related disorders: consensus on new nomenclature and classification
Authors: Anna Sapone
Julio C Bai
Carolina Ciacci
Jernej Dolinsek
Peter HR Green
Marios Hadjivassiliou
Katri Kaukinen
Kamran Rostami
David S Sanders
Michael Schumann
Reiner Ullrich
Danilo Villalta
Umberto Volta
Carlo Catassi
Alessio Fasano
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: BMC Medicine / Issue 1/2012
Electronic ISSN: 1741-7015
DOI: https://doi.org/10.1186/1741-7015-10-13

Keynote webinar | Spotlight on medication adherence

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Spectrum of gluten-related disorders: consensus on new nomenclature and classification

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Keynote webinar | Spotlight on medication adherence

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