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Published in: BMC Medicine 1/2012

Open Access 01-12-2012 | Minireview

Personalized medicine in multiple sclerosis: hope or reality?

Author: Tobias Derfuss

Published in: BMC Medicine | Issue 1/2012

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Abstract

Personalized treatment is highly desirable in multiple sclerosis because it is an immensely heterogeneous disease. This heterogeneity is seen in both the disease course and the treatment responses. Currently, a combination of clinical features and imaging parameters in magnetic resonance imaging is used to classify active and non-active patients and treatment responders and non-responders. Although this classification works on a group level, individual patients often behave differently from the group. Therefore additional biomarkers are needed to provide better indicators for prognosis and treatment response. Basic and clinical research have discovered different promising targets. It is now essential to verify the utility and accuracy of these markers in large, prospectively sampled patient cohorts.
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Metadata
Title
Personalized medicine in multiple sclerosis: hope or reality?
Author
Tobias Derfuss
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2012
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/1741-7015-10-116

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