Published in:
Open Access
01-03-2014 | Meeting abstract
Comparison of questionnaire responses with biomarkers of tobacco smoke exposure in a Canadian birth cohort at three months of age
Authors:
Kathleen McLean, Bruce Lanphear, Amanda J Wheeler, Jeff Brook, James Scott, Ryan Allen, Michael Brauer, Malcolm Sears, Padmaja Subbarao, Stuart Turvey, Allan Becker, Piush Mandhane, Tim Takaro
Published in:
Allergy, Asthma & Clinical Immunology
|
Special Issue 1/2014
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Excerpt
Exposure to tobacco smoke increases the risk for several adverse health effects in children including wheeze, asthma, and asthma exacerbation [
1,
2]. Accurately assessing tobacco smoke exposure is important for understanding and preventing these health effects. Questionnaires are a flexible and relatively inexpensive method of assessing exposure, but biomarkers of tobacco smoke exposure are considered more accurate. We developed questionnaire-based exposure models predicting urinary levels of biomarkers cotinine and
trans-3’-hydroxycotinine (3HC) (metabolites of nicotine) in 3-month old infants using parent-reported questionnaire responses about tobacco smoke exposure from the Canadian Healthy Infant Longitudinal Development (CHILD) Study. …
