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Pediatric Rheumatology
Published in: Pediatric Rheumatology 1/2011

Open Access 01-12-2011 | Poster presentation

Interleukin-1 antagonists in Mevalonate Kinase Deficiency

Authors: C Galeotti, L Rossi-Semerano, S Guillaume, A Duquesne, P Pillet, O Richer, E Hachulla, I Koné-Paut

Published in: Pediatric Rheumatology | Special Issue 1/2011

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Excerpt

Mevalonate Kinase Deficiency (MKD) is one of the autoinflammatory fever syndromes, caused by mutations in the MKD gene. Systemic inflammatory symptoms may be mild to severe leading to early death, and recurrent bacterial infections frequently develop in the disease course. On demand NSAID and steroids are the most commonly used. Few case-reports suggested that interleukin-1 (IL-1) antagonists could alleviate MKD symptoms. …
Metadata
Title
Interleukin-1 antagonists in Mevalonate Kinase Deficiency
Authors
C Galeotti
L Rossi-Semerano
S Guillaume
A Duquesne
P Pillet
O Richer
E Hachulla
I Koné-Paut
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue Special Issue 1/2011
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-9-S1-P7

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