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Pediatric Rheumatology
Published in: Pediatric Rheumatology 1/2011

Open Access 01-12-2011 | Case Report

Partial response to anakinra in life-threatening Henoch-Schönlein purpura: case report

Authors: Erynn M Boyer, Martin Turman, Kathleen M O'Neil

Published in: Pediatric Rheumatology | Issue 1/2011

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Abstract

Henoch-Schönlein purpura is one of the most common forms of systemic vasculitis of childhood. We report the response to anakinra, the interleukin-1 receptor antagonist, in a 9 year old girl without prior medical problems who developed life-threatening Henoch-Schönlein vasculitis that produced renal failure, pulmonary hemorrhage and vasculitis of the brain. Her response supports the theory that interleukin-1 may be an important mediator in this disease. Further study of interleukin-1 antagonists in severe Henoch-Schönlein purpura may be warranted.
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Metadata
Title
Partial response to anakinra in life-threatening Henoch-Schönlein purpura: case report
Authors
Erynn M Boyer
Martin Turman
Kathleen M O'Neil
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue 1/2011
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-9-21

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