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Published in: Pediatric Rheumatology 1/2014

Open Access 01-09-2014 | Poster presentation

Elicitation of expert prior opinion: application to the mypan trial in childhood polyarteritis nodosa

Authors: Lisa Hampson, John Whitehead, Despina Eleftheriou, Catherine Tudur-Smith, Rachel Jones, David Jayne, Helen Hickey, Paul Brogan, MYPAN vasculitis expert group

Published in: Pediatric Rheumatology | Special Issue 1/2014

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Excerpt

A major challenge in rare diseases is conducting clinical trials with sufficient power to inform best clinical practice when anticipated sample sizes are small. Historically, this has been a major barrier in rare paediatric autoimmune diseases. Bayesian methodology can be used to augment the sparse therapeutic data obtained from clinical trials in these circumstances. …
Metadata
Title
Elicitation of expert prior opinion: application to the mypan trial in childhood polyarteritis nodosa
Authors
Lisa Hampson
John Whitehead
Despina Eleftheriou
Catherine Tudur-Smith
Rachel Jones
David Jayne
Helen Hickey
Paul Brogan
MYPAN vasculitis expert group
Publication date
01-09-2014
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue Special Issue 1/2014
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-12-S1-P125

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