Published in:
Open Access
01-01-2014 | Poster presentation
CMR trabecular fractal analysis - technical development of a measurement system
Authors:
Gaby Captur, Vivek Muthurangu, Gherardo Finocchiaro, Filip Zemrak, Vanessa M Ferreira, Songtao Liu, Chunming Li, Steffen E Petersen, William J McKenna, Timothy J Mohun, David Bluemke, Perry M Elliott, James Moon
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2014
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Excerpt
Cardiac trabeculae are complex and difficult to quantify but measuring their biological signal in many cardiac diseases (left ventricular [LV] non-compaction, hypertrophic cardiomyopathy [HCM]) has value. We have recently shown how trabeculae differ between ethnicities in health and between HCM mutation carriers without hypertrophy and healthy volunteers. Here we present a novel tool for measurement for LV trabecular complexity by cardiovascular magnetic resonance (CMR) using a fractal analysis. Theoretical fundamentals are discussed. They include the measurement procedure, mathematical modeling and performance evaluation through validation by digital phantoms and reproducibility analysis when applied to real-world cardiac data. …
