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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-01-2014 | Poster presentation

Native T1 values in discrimination of subclinical profibrotic phenotype in relatives of patients with hypertrophic cardiomyopathy

Authors: Rocio Hinojar, Benjamin P Goodman, Adriana Villa, Darius Dabir, Eduardo Arroyo Ucar, Thomas Jackson, Tobias Schaeffter, Eike Nagel, Valentina Puntmann

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2014

Excerpt

Hypertrophic cardiomyopathy (HCM) is associated with significant associated morbidity and mortality. Increased maximal left ventricular wall thickness (LVWT) has been postulated as major risk factor of sudden death; however, relatives with normal LVWT are also at risk. Genetically driven interstitial collagenesis has been proposed as a possible mechanism of diffuse myocardial fibrosis and increased extracellular volume fractions (ECV) has been demonstrated in genotype positive subjects. We investigated whether native T1 can also separate genotype positive subjects in the absence of increase in LVWT and how does it relate to ECV measurements. …

Title: Native T1 values in discrimination of subclinical profibrotic phenotype in relatives of patients with hypertrophic cardiomyopathy
Authors: Rocio Hinojar
Benjamin P Goodman
Adriana Villa
Darius Dabir
Eduardo Arroyo Ucar
Thomas Jackson
Tobias Schaeffter
Eike Nagel
Valentina Puntmann
Publication date: 01-01-2014
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue Special Issue 1/2014
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/1532-429X-16-S1-P241

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Native T1 values in discrimination of subclinical profibrotic phenotype in relatives of patients with hypertrophic cardiomyopathy

Excerpt

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