Published in:
Open Access
01-01-2014 | Oral presentation
Evaluation of iron overload: dual-energy computed tomography versus magnetic resonance imaging
Authors:
El-Sayed H Ibrahim, Andrew W Bowman
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2014
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Excerpt
Iron toxicity is key factor for tissue damage in iron-overloaded patients, with induced heart failure as the main cause of death. T2*-weighted MRI has been established as the method of choice for evaluating iron-content with strong correlation with biopsy, where T2* < 20 ms and T2* < 10 ms at 1.5T indicate iron overload and severe iron overload, respectively. Recently-introduced dual-energy CT (DECT) has the potential for evaluating iron overload without energy-dependent CT attenuation or tissue fat effects. The aim of this study is to investigate the performance of DECT for iron mapping in in-vitro scans of calibrated iron phantoms and compare results to MRI. …