Published in:
Open Access
01-01-2013 | Poster presentation
Associated factors for a false negative cardiovascular magnetic resonance perfusion study: a CE-MARC substudy
Authors:
Sven Plein, Ananth Kidambi, Steven Sourbron, Neil Maredia, Akhlaque Uddin, Manish Motwani, David P Ripley, Bernhard A Herzog, Julia Brown, Jane Nixon, Colin Everett, John P Greenwood
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2013
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Excerpt
Diagnosis of coronary ischemia by perfusion CMR has high sensitivity and specificity when using X-ray coronary angiography as the reference standard. A variety of possible reasons have been given for false negative perfusion CMR studies, such as suboptimal image quality, technical reasons, or the potential discrepancy between angiographic stenosis and detectable myocardial hypoperfusion. The rates at which these factors occur have not been specifically studied to date. The CE-MARC study prospectively enrolled 752 patients with suspected coronary artery disease, scheduled to undergo CMR, SPECT and X-ray coronary angiography [
1]. We assessed potential reasons for the false negative CMR perfusion studies within CE-MARC. …