Published in:
Open Access
01-01-2013 | Oral presentation
Late gadolinium enhancement cardiovascular magnetic resonance for sudden cardiac death risk stratification in hypertrophic cardiomyopathy
Authors:
Tevfik F Ismail, Andrew Jabbour, Ankur Gulati, Amy Mallorie, Sadaf Raza, Thomas E Cowling, Bibek Das, Jahanzaib Khwaja, Rick Wage, James Moon, Amanda Varnava, Carl Shakespeare, Perry Elliott, Rory OHanlon, Dudley J Pennell, Sanjay K Prasad
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2013
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Excerpt
Although myocardial fibrosis identified by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) may predict adverse outcomes among patients with hypertrophic cardiomyopathy (HCM), its precise role in risk stratification for sudden cardiac death (SCD) remains unresolved. Previous studies have relied on broad surrogate composite endpoints and were underpowered to assess SCD risk or to adjust for confounding variables. To address this, we studied the prognostic significance of LGE in a large HCM cohort with long-term follow-up. …