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Published in: Cost Effectiveness and Resource Allocation 1/2013

Open Access 01-12-2013 | Research

Efficient and equitable HIV prevention: A case study of male circumcision in South Africa

Author: Stéphane Verguet

Published in: Cost Effectiveness and Resource Allocation | Issue 1/2013

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Abstract

Background

We determine efficient, equitable and mixed efficient-equitable allocations of a male circumcision (MC) intervention reducing female to male HIV transmission in South Africa (SA), as a case study of an efficiency-equity framework for resource allocation in HIV prevention.

Methods

We present a mathematical model developed with epidemiological and cost data from the nine provinces of SA. The hypothetical one-year-long MC intervention with a budget of US$ 10 million targeted adult men 15–49 years of age in SA. The intervention was evaluated according to two criteria: an efficiency criterion, which focused on maximizing the number of HIV infections averted by the intervention, and an equity criterion (defined geographically), which focused on maximizing the chance that each male adult individual had access to the intervention regardless of his province.

Results

A purely efficient intervention would prevent 4,008 HIV infections over a year. In the meantime, a purely equitable intervention would avert 3,198 infections, which represents a 20% reduction in infection outcome as compared to the purely efficient scenario. A half efficient-half equitable scenario would prevent 3,749 infections, that is, a 6% reduction in infection outcome as compared to the purely efficient scenario.

Conclusions

This paper provides a framework for resource allocation in the health sector which incorporates a simple equity metric in addition to efficiency. In the specific context of SA with a MC intervention for the prevention of HIV, incorporation of geographical equity only slightly reduces the overall efficiency of the intervention.
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Literature
2.
go back to reference Abdool Karim Q: South Africa: host to a new and emerging HIV epidemic. Sex Transm Infect 1999, 75: 139–147. 10.1136/sti.75.3.139CrossRefPubMed Abdool Karim Q: South Africa: host to a new and emerging HIV epidemic. Sex Transm Infect 1999, 75: 139–147. 10.1136/sti.75.3.139CrossRefPubMed
3.
go back to reference Lurie MN, Williams BG, Zuma K, Mkaya-Mwamburi D, Garnett GP, Sturm A, Sweat M, Gittelsohn J, Abdool Karim SS: The impact of migration on HIV-1 transmission in South Africa. Sex Transm Dis 2003, 30(2):149–156. 10.1097/00007435-200302000-00011CrossRefPubMed Lurie MN, Williams BG, Zuma K, Mkaya-Mwamburi D, Garnett GP, Sturm A, Sweat M, Gittelsohn J, Abdool Karim SS: The impact of migration on HIV-1 transmission in South Africa. Sex Transm Dis 2003, 30(2):149–156. 10.1097/00007435-200302000-00011CrossRefPubMed
4.
go back to reference Hargrove JW: Migration, mines and mores: the HIV epidemic in Southern Africa. S Afr J Sci 2008, 104: 53–61. Hargrove JW: Migration, mines and mores: the HIV epidemic in Southern Africa. S Afr J Sci 2008, 104: 53–61.
5.
go back to reference Chigwedere P, Seage GR III, Gruskin S, Lee TH, Essex M: Estimating the lost benefits of antiretroviral drug use in South Africa. AIDS 2008, 49(4):410–415. Chigwedere P, Seage GR III, Gruskin S, Lee TH, Essex M: Estimating the lost benefits of antiretroviral drug use in South Africa. AIDS 2008, 49(4):410–415.
6.
go back to reference Celentano DD, Nelson KE, Lyles CM, Beyrer C, Eiumtrakul S, Go V, Kuntolbutra S, Khamboonruang C: Decreasing incidence of HIV and sexually transmitted diseases in young Thai men: evidence for success of the HIV/AIDS control and prevention program. AIDS 1998, 12: F29-F36. 10.1097/00002030-199805000-00004CrossRefPubMed Celentano DD, Nelson KE, Lyles CM, Beyrer C, Eiumtrakul S, Go V, Kuntolbutra S, Khamboonruang C: Decreasing incidence of HIV and sexually transmitted diseases in young Thai men: evidence for success of the HIV/AIDS control and prevention program. AIDS 1998, 12: F29-F36. 10.1097/00002030-199805000-00004CrossRefPubMed
7.
go back to reference Green EC, Halperin DT, Nantulya V, Hogle JA: Uganda’s HIV prevention success: the role of sexual behavior change. AIDS Behav 2006, 10(4):335–346. 10.1007/s10461-006-9073-yPubMedCentralCrossRefPubMed Green EC, Halperin DT, Nantulya V, Hogle JA: Uganda’s HIV prevention success: the role of sexual behavior change. AIDS Behav 2006, 10(4):335–346. 10.1007/s10461-006-9073-yPubMedCentralCrossRefPubMed
8.
go back to reference Potts M, Halperin DT, Kirby D, Swidler A, Marseille E, Klausner JD, Hearst N, Wamai RG, Kahn JG, Walsh J: Reassessing HIV prevention. Science 2008, 320: 749–750. 10.1126/science.1153843PubMedCentralCrossRefPubMed Potts M, Halperin DT, Kirby D, Swidler A, Marseille E, Klausner JD, Hearst N, Wamai RG, Kahn JG, Walsh J: Reassessing HIV prevention. Science 2008, 320: 749–750. 10.1126/science.1153843PubMedCentralCrossRefPubMed
9.
go back to reference Piot P: AIDS: from crisis management to sustained strategic response. Lancet 2006, 368: S26–30.CrossRef Piot P: AIDS: from crisis management to sustained strategic response. Lancet 2006, 368: S26–30.CrossRef
10.
go back to reference Wegbreit J, Bertozzi S, DeMaria LM, Padian N: Effectiveness of HIV prevention strategies in resource-poor countries: tailoring the intervention to the context. AIDS 2006, 20(9):1217–1235. 10.1097/01.aids.0000232229.96134.56CrossRefPubMed Wegbreit J, Bertozzi S, DeMaria LM, Padian N: Effectiveness of HIV prevention strategies in resource-poor countries: tailoring the intervention to the context. AIDS 2006, 20(9):1217–1235. 10.1097/01.aids.0000232229.96134.56CrossRefPubMed
11.
go back to reference Weiss HA, Quigley MA, Hayes RJ: Male circumcision and risk of HIV infection in Sub-Saharan Africa: a systematic review and meta-analysis. AIDS 2000, 14: 2361–2370. 10.1097/00002030-200010200-00018CrossRefPubMed Weiss HA, Quigley MA, Hayes RJ: Male circumcision and risk of HIV infection in Sub-Saharan Africa: a systematic review and meta-analysis. AIDS 2000, 14: 2361–2370. 10.1097/00002030-200010200-00018CrossRefPubMed
12.
go back to reference Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A: Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 Trial. PLoS Med 2005, 2(11):e298. 10.1371/journal.pmed.0020298PubMedCentralCrossRefPubMed Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A: Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 Trial. PLoS Med 2005, 2(11):e298. 10.1371/journal.pmed.0020298PubMedCentralCrossRefPubMed
13.
go back to reference Bailey RC, Moses S, Parker CB, Agot K, Maclean I, Krieger JN, Williams CFM, Campbell RT, Ndinya-Achola JO: Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomized controlled trial. Lancet 2007, 369: 643–656. 10.1016/S0140-6736(07)60312-2CrossRefPubMed Bailey RC, Moses S, Parker CB, Agot K, Maclean I, Krieger JN, Williams CFM, Campbell RT, Ndinya-Achola JO: Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomized controlled trial. Lancet 2007, 369: 643–656. 10.1016/S0140-6736(07)60312-2CrossRefPubMed
14.
go back to reference Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, Kiwanuka N, Moulton LH, Chaudhary MA, Chen MZ, Sewankambo NK, Wabwire-Mangen F, Bacon MC, Williams CFM, Opendi P, Reynolds SJ, Laeyendecker O, Quinn TC, Wawer M: Male circumcision for HIV prevention in men in Rakai, Uganda: a randomized trial. Lancet 2007, 369: 657–666. 10.1016/S0140-6736(07)60313-4CrossRefPubMed Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, Kiwanuka N, Moulton LH, Chaudhary MA, Chen MZ, Sewankambo NK, Wabwire-Mangen F, Bacon MC, Williams CFM, Opendi P, Reynolds SJ, Laeyendecker O, Quinn TC, Wawer M: Male circumcision for HIV prevention in men in Rakai, Uganda: a randomized trial. Lancet 2007, 369: 657–666. 10.1016/S0140-6736(07)60313-4CrossRefPubMed
15.
go back to reference Williams BG, Lloyd-Smith JO, Gouws E, Hankins C, Getz W, Hargorve J, de Zoysa I, Dye C, Auvert B: The potential impact of male circumcision on HIV in Sub-Saharan Africa. PLoS Med 2006, 3(7):e262. 10.1371/journal.pmed.0030262PubMedCentralCrossRefPubMed Williams BG, Lloyd-Smith JO, Gouws E, Hankins C, Getz W, Hargorve J, de Zoysa I, Dye C, Auvert B: The potential impact of male circumcision on HIV in Sub-Saharan Africa. PLoS Med 2006, 3(7):e262. 10.1371/journal.pmed.0030262PubMedCentralCrossRefPubMed
16.
go back to reference Kahn JG, Marseille E, Auvert B: Cost-effectiveness of male circumcision for HIV prevention in a South African setting. PLoS Med 2006, 3(12):e7.CrossRef Kahn JG, Marseille E, Auvert B: Cost-effectiveness of male circumcision for HIV prevention in a South African setting. PLoS Med 2006, 3(12):e7.CrossRef
17.
go back to reference Bertozzi S, Padian NS, Wegbreit J, DeMaria LM, Feldman B, Gayle H, Gold J, Grant R, Isbell MT: HIV/AIDS prevention and treatment. In Disease Control Priorities in Developing Countries. Edited by: Jamison DT, Breman JG, Measham AR, Alleyne G, Clamson M, Evans DB, Jha P, Mills A, Musgrove P. The World Bank Group, Washington DC; 2006. Bertozzi S, Padian NS, Wegbreit J, DeMaria LM, Feldman B, Gayle H, Gold J, Grant R, Isbell MT: HIV/AIDS prevention and treatment. In Disease Control Priorities in Developing Countries. Edited by: Jamison DT, Breman JG, Measham AR, Alleyne G, Clamson M, Evans DB, Jha P, Mills A, Musgrove P. The World Bank Group, Washington DC; 2006.
18.
go back to reference Westercamp N, Bailey RC: Acceptability of male circumcision for prevention of HIV/AIDS in Sub-Saharan Africa: a review. AIDS Behav 2007, 11: 341–355. 10.1007/s10461-006-9169-4PubMedCentralCrossRefPubMed Westercamp N, Bailey RC: Acceptability of male circumcision for prevention of HIV/AIDS in Sub-Saharan Africa: a review. AIDS Behav 2007, 11: 341–355. 10.1007/s10461-006-9169-4PubMedCentralCrossRefPubMed
19.
go back to reference McIntyre D, Gilson L: Putting equity in health back onto the social policy agenda: experience from South Africa. Soc Sci Med 2002, 54: 1637–1656. 10.1016/S0277-9536(01)00332-XCrossRefPubMed McIntyre D, Gilson L: Putting equity in health back onto the social policy agenda: experience from South Africa. Soc Sci Med 2002, 54: 1637–1656. 10.1016/S0277-9536(01)00332-XCrossRefPubMed
22.
go back to reference Baltussen R, Niessen L: Priority setting of health interventions: the need for multi-criteria decision analysis. Cost Effective Resour Allocat 2006, 4: 14. 10.1186/1478-7547-4-14CrossRef Baltussen R, Niessen L: Priority setting of health interventions: the need for multi-criteria decision analysis. Cost Effective Resour Allocat 2006, 4: 14. 10.1186/1478-7547-4-14CrossRef
23.
go back to reference Kaplan EH, Merson MH: Allocating HIV-prevention resources: balancing efficiency and equity. Am J Public Health 2002, 92(12):1905–1907. 10.2105/AJPH.92.12.1905PubMedCentralCrossRefPubMed Kaplan EH, Merson MH: Allocating HIV-prevention resources: balancing efficiency and equity. Am J Public Health 2002, 92(12):1905–1907. 10.2105/AJPH.92.12.1905PubMedCentralCrossRefPubMed
24.
go back to reference Cleary S: Equity and efficiency in scaling up access to HIV-related interventions in resource-limited settings. Curr Opin HIV AIDS 5: 210–214. Cleary S: Equity and efficiency in scaling up access to HIV-related interventions in resource-limited settings. Curr Opin HIV AIDS 5: 210–214.
25.
go back to reference Segall RS: Some nonlinear optimization modeling for planning objectives of large market-oriented systems: with an application to real health data. Appl Math Model 1989, 13: 203–214. 10.1016/0307-904X(89)90078-4CrossRef Segall RS: Some nonlinear optimization modeling for planning objectives of large market-oriented systems: with an application to real health data. Appl Math Model 1989, 13: 203–214. 10.1016/0307-904X(89)90078-4CrossRef
26.
go back to reference Birch S, Gafni A: Cost-effectiveness/utility analyses. Do current decisions lead us to where we want to be? J Health Econ 1992, 11: 279–296. 10.1016/0167-6296(92)90004-KCrossRefPubMed Birch S, Gafni A: Cost-effectiveness/utility analyses. Do current decisions lead us to where we want to be? J Health Econ 1992, 11: 279–296. 10.1016/0167-6296(92)90004-KCrossRefPubMed
27.
go back to reference Stinnett AA, Paltiel DA: Mathematical programming for the efficient allocation of health care resources. J Health Econ 1996, 15: 641–653. 10.1016/S0167-6296(96)00493-6CrossRefPubMed Stinnett AA, Paltiel DA: Mathematical programming for the efficient allocation of health care resources. J Health Econ 1996, 15: 641–653. 10.1016/S0167-6296(96)00493-6CrossRefPubMed
28.
go back to reference Bleichrodt H, Diecidue E, Quiggin J: Equity weights in the allocation of health care: the rank-dependent QALY model. J Health Econ 2004, 23: 157–171. 10.1016/j.jhealeco.2003.08.002CrossRefPubMed Bleichrodt H, Diecidue E, Quiggin J: Equity weights in the allocation of health care: the rank-dependent QALY model. J Health Econ 2004, 23: 157–171. 10.1016/j.jhealeco.2003.08.002CrossRefPubMed
29.
go back to reference Epstein D, Chalabi Z, Claxton K, Sculpher M: Efficiency, Equity, and Budgetary Policies: Informing Decisions Using Mathematical Programming. Med Decis Mak 2007, 27: 128–137. 10.1177/0272989X06297396CrossRef Epstein D, Chalabi Z, Claxton K, Sculpher M: Efficiency, Equity, and Budgetary Policies: Informing Decisions Using Mathematical Programming. Med Decis Mak 2007, 27: 128–137. 10.1177/0272989X06297396CrossRef
30.
go back to reference Earnshaw SR, Hicks K, Richter A, Honeycutt A: A linear programming model for allocating HIV prevention funds with state agencies: a pilot study. Health Care Manag Sci 2007, 10: 239–252. 10.1007/s10729-007-9017-8CrossRefPubMed Earnshaw SR, Hicks K, Richter A, Honeycutt A: A linear programming model for allocating HIV prevention funds with state agencies: a pilot study. Health Care Manag Sci 2007, 10: 239–252. 10.1007/s10729-007-9017-8CrossRefPubMed
31.
go back to reference Lasry A, Zaric GS, Carter MW: Multi-level resource allocation for HIV prevention: A model for developing countries. Eur J Oper Res 2007, 18: 786–799.CrossRef Lasry A, Zaric GS, Carter MW: Multi-level resource allocation for HIV prevention: A model for developing countries. Eur J Oper Res 2007, 18: 786–799.CrossRef
32.
go back to reference Richter A, Hicks KA, Earnshaw SR, Honeycutt AA: Allocating HIV prevention resources: A tool for state and local decision making. Health Policy 2008, 87: 342–349. 10.1016/j.healthpol.2008.01.008CrossRefPubMed Richter A, Hicks KA, Earnshaw SR, Honeycutt AA: Allocating HIV prevention resources: A tool for state and local decision making. Health Policy 2008, 87: 342–349. 10.1016/j.healthpol.2008.01.008CrossRefPubMed
33.
go back to reference Lasry A, Carter MW, Zaric GS: S4HARA: System for HIV/AIDS resource allocation. Cost Effective Resour Allocat 2008, 6: 7. 10.1186/1478-7547-6-7CrossRef Lasry A, Carter MW, Zaric GS: S4HARA: System for HIV/AIDS resource allocation. Cost Effective Resour Allocat 2008, 6: 7. 10.1186/1478-7547-6-7CrossRef
34.
go back to reference Cleary S, Mooney G, McIntyre D: Equity and Efficiency in HIV-treatment in South Africa: The contribution of mathematical programming to priority setting. Health Econ 2010, 19(10):1166–1180. 10.1002/hec.1542CrossRefPubMed Cleary S, Mooney G, McIntyre D: Equity and Efficiency in HIV-treatment in South Africa: The contribution of mathematical programming to priority setting. Health Econ 2010, 19(10):1166–1180. 10.1002/hec.1542CrossRefPubMed
35.
go back to reference Auvert B, Marseille E, Korenromp EL, Lloyd-Smith J, Sitta R, Taljaard D, Pretorius C, Williams B, Kahn JG: Estimating the resources needed and savings anticipated from roll-out of adult male circumcision in Sub-Saharan Africa. PLoS One 2008, 3(8):e2679. 10.1371/journal.pone.0002679PubMedCentralCrossRefPubMed Auvert B, Marseille E, Korenromp EL, Lloyd-Smith J, Sitta R, Taljaard D, Pretorius C, Williams B, Kahn JG: Estimating the resources needed and savings anticipated from roll-out of adult male circumcision in Sub-Saharan Africa. PLoS One 2008, 3(8):e2679. 10.1371/journal.pone.0002679PubMedCentralCrossRefPubMed
36.
go back to reference Shisana O, Rehle T, Simbayi LC, Zuma K, Jooste S, Pillay-van-Wyk V, Mbelle N, Van Zyl J, Parker W, Zungu NP, Pezi S & the SABSSM III Implementation Team: South African national HIV prevalence, incidence, behaviour, and communication survey 2008: a turning tide among teenagers?. HSRC Press, Cape Town; 2009. Shisana O, Rehle T, Simbayi LC, Zuma K, Jooste S, Pillay-van-Wyk V, Mbelle N, Van Zyl J, Parker W, Zungu NP, Pezi S & the SABSSM III Implementation Team: South African national HIV prevalence, incidence, behaviour, and communication survey 2008: a turning tide among teenagers?. HSRC Press, Cape Town; 2009.
37.
go back to reference Statistics South Africa: The people of South Africa: population census 1996, census in brief/Statistics South Africa. Statistics South Africa, Pretoria; 1998. Statistics South Africa: The people of South Africa: population census 1996, census in brief/Statistics South Africa. Statistics South Africa, Pretoria; 1998.
38.
go back to reference Department of Health, ORC Macro: South Africa Demographic and Health Survey 2003: preliminary report. Department of Health, Pretoria; 2004. Department of Health, ORC Macro: South Africa Demographic and Health Survey 2003: preliminary report. Department of Health, Pretoria; 2004.
39.
go back to reference Weiss HA, Hankins CA, Dickson K: Male circumcision and risk of HIV infection in women: a systematic review and meta-analysis. Lancet 2009, 9: 669–677.CrossRefPubMed Weiss HA, Hankins CA, Dickson K: Male circumcision and risk of HIV infection in women: a systematic review and meta-analysis. Lancet 2009, 9: 669–677.CrossRefPubMed
40.
go back to reference Pinkerton SD, Abramson PR: The Bernoulli-process of HIV transmission: applications and implications. Plenum Press, New York, In Handbook of economic evaluation of HIV prevention programs Edited by Holtgrave DR; 1998. Pinkerton SD, Abramson PR: The Bernoulli-process of HIV transmission: applications and implications. Plenum Press, New York, In Handbook of economic evaluation of HIV prevention programs Edited by Holtgrave DR; 1998.
41.
go back to reference Boily MC, Baggaley RF, Wang L, Masse B, White RG, Hayes RJ, Alary M: Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies. Lancet Infect Dis 2009, 9: 118–129. 10.1016/S1473-3099(09)70021-0PubMedCentralCrossRefPubMed Boily MC, Baggaley RF, Wang L, Masse B, White RG, Hayes RJ, Alary M: Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies. Lancet Infect Dis 2009, 9: 118–129. 10.1016/S1473-3099(09)70021-0PubMedCentralCrossRefPubMed
42.
go back to reference Wawer M, Gray RH, Sewankambo NK, Serwadda D, Li X, Laeyendecker O, Kiwanuka N, Kigozi G, Kiddugavu M, Lutalo T, Nalugoda F, Wabwire-Mangen F, Meehan MP, Quinn TC: Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis 2005, 191: 1403–1409. 10.1086/429411CrossRefPubMed Wawer M, Gray RH, Sewankambo NK, Serwadda D, Li X, Laeyendecker O, Kiwanuka N, Kigozi G, Kiddugavu M, Lutalo T, Nalugoda F, Wabwire-Mangen F, Meehan MP, Quinn TC: Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis 2005, 191: 1403–1409. 10.1086/429411CrossRefPubMed
43.
go back to reference Pinkerton SD, Abramson PR: Effectiveness of condoms in preventing HIV transmission. Soc Sci Med 1997, 44(9):1003–1012.CrossRef Pinkerton SD, Abramson PR: Effectiveness of condoms in preventing HIV transmission. Soc Sci Med 1997, 44(9):1003–1012.CrossRef
44.
go back to reference Wilson DP, Blower SM: Designing equitable antiretroviral allocation strategies in resource-constrained countries. PLoS Med 2005, 2(2):e50. 10.1371/journal.pmed.0020050PubMedCentralCrossRefPubMed Wilson DP, Blower SM: Designing equitable antiretroviral allocation strategies in resource-constrained countries. PLoS Med 2005, 2(2):e50. 10.1371/journal.pmed.0020050PubMedCentralCrossRefPubMed
45.
go back to reference Kalichman S, Eaton L, Pinkerton S: Circumcision for HIV prevention: failure to fully account for behavioral risk compensation. PLoS Med 2007, 4(3):e138. 10.1371/journal.pmed.0040138PubMedCentralCrossRefPubMed Kalichman S, Eaton L, Pinkerton S: Circumcision for HIV prevention: failure to fully account for behavioral risk compensation. PLoS Med 2007, 4(3):e138. 10.1371/journal.pmed.0040138PubMedCentralCrossRefPubMed
46.
go back to reference Wilson DP, Kahn J, Blower SM: Predicting the epidemiological impact of antiretroviral allocation strategies in KwaZulu-Natal: The effect of the urban–rural divide. Proc Natl Acad Sci 2006, 103(38):14228–14233. 10.1073/pnas.0509689103PubMedCentralCrossRefPubMed Wilson DP, Kahn J, Blower SM: Predicting the epidemiological impact of antiretroviral allocation strategies in KwaZulu-Natal: The effect of the urban–rural divide. Proc Natl Acad Sci 2006, 103(38):14228–14233. 10.1073/pnas.0509689103PubMedCentralCrossRefPubMed
47.
go back to reference Noor AM, Zurovac D, Hay SI, Ochola SA, Snow RW: Defining equity in physical access to clinical services using geographical information systems as part of malaria planning and monitoring in Kenya. Trop Med Int Health 2003, 8(10):917–926. 10.1046/j.1365-3156.2003.01112.xPubMedCentralCrossRefPubMed Noor AM, Zurovac D, Hay SI, Ochola SA, Snow RW: Defining equity in physical access to clinical services using geographical information systems as part of malaria planning and monitoring in Kenya. Trop Med Int Health 2003, 8(10):917–926. 10.1046/j.1365-3156.2003.01112.xPubMedCentralCrossRefPubMed
Metadata
Title
Efficient and equitable HIV prevention: A case study of male circumcision in South Africa
Author
Stéphane Verguet
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Cost Effectiveness and Resource Allocation / Issue 1/2013
Electronic ISSN: 1478-7547
DOI
https://doi.org/10.1186/1478-7547-11-1

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