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Open Access 01-12-2009 | Review

Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system

Authors: Nisarg R Desai, Kavindra K Kesari, Ashok Agarwal

Published in: Reproductive Biology and Endocrinology | Issue 1/2009

Abstract

Hazardous health effects stemming from exposure to radiofrequency electromagnetic waves (RF-EMW) emitted from cell phones have been reported in the literature. However, the cellular target of RF-EMW is still controversial. This review identifies the plasma membrane as a target of RF-EMW. In addition, the effects of RF-EMW on plasma membrane structures (i.e. NADH oxidase, phosphatidylserine, ornithine decarboxylase) and voltage-gated calcium channels are discussed. We explore the disturbance in reactive oxygen species (ROS) metabolism caused by RF-EMW and delineate NADH oxidase mediated ROS formation as playing a central role in oxidative stress (OS) due to cell phone radiation (with a focus on the male reproductive system). This review also addresses: 1) the controversial effects of RF-EMW on mammalian cells and sperm DNA as well as its effect on apoptosis, 2) epidemiological, in vivo animal and in vitro studies on the effect of RF-EMW on male reproductive system, and 3) finally, exposure assessment and dosimetry by computational biomodeling.

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Title: Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system
Authors: Nisarg R Desai
Kavindra K Kesari
Ashok Agarwal
Publication date: 01-12-2009
Publisher: BioMed Central
Published in: Reproductive Biology and Endocrinology / Issue 1/2009
Electronic ISSN: 1477-7827
DOI: https://doi.org/10.1186/1477-7827-7-114

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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