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Published in: Reproductive Biology and Endocrinology 1/2008

Open Access 01-12-2008 | Research

The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome

Authors: Ahlam Al-Ghamdi, Serdar Coskun, Saad Al-Hassan, Rafat Al-Rejjal, Khalid Awartani

Published in: Reproductive Biology and Endocrinology | Issue 1/2008

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Abstract

Background

To evaluate the relationship between endometrial thickness on day of human chorionic gonadotrophin administration (hCG) and pregnancy outcome in a large number of consecutive in vitro fertilization and embryo transfer (IVF-ET) cycles.

Methods

A retrospective cohort study including all patients who had IVF-ET from January 2003–December 2005 conducted at a tertiary center.

Results

A total of 2464 cycles were analysed. Pregnancy rate (PR) was 35.8%. PR increased linearly (r = 0.864) from 29.4% among patients with a lining of less than or equal to 6 mm, to 44.4% among patients with a lining of greater than or equal to 17 mm. ROC showed that endometrial thickness is not a good predictor of PR, so a definite cut-off value could not be established (AUC = 0.55).

Conclusion

There is a positive linear relationship between the endometrial thickness measured on the day of hCG injection and PR, and is independent of other variables. Hence aiming for a thicker endometrium should be considered.
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Metadata
Title
The correlation between endometrial thickness and outcome of in vitro fertilization and embryo transfer (IVF-ET) outcome
Authors
Ahlam Al-Ghamdi
Serdar Coskun
Saad Al-Hassan
Rafat Al-Rejjal
Khalid Awartani
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Reproductive Biology and Endocrinology / Issue 1/2008
Electronic ISSN: 1477-7827
DOI
https://doi.org/10.1186/1477-7827-6-37

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