Top

Published in:

Open Access 01-12-2011 | Review

Focus on the research utility of intravascular ultrasound - comparison with other invasive modalities

Authors: Christos V Bourantas, Scot Garg, Katerina K Naka, Attila Thury, Angela Hoye, Lampros K Michalis

Published in: Cardiovascular Ultrasound | Issue 1/2011

Abstract

Intravascular ultrasound (IVUS) is an invasive modality which provides cross-sectional images of a coronary artery. In these images both the lumen and outer vessel wall can be identified and accurate estimations of their dimensions and of the plaque burden can be obtained. In addition, further processing of the IVUS backscatter signal helps in the characterization of the type of the plaque and thus it has been used to study the natural history of the atherosclerotic evolution. On the other hand its indigenous limitations do not allow IVUS to assess accurately stent struts coverage, existence of thrombus or exact site of plaque rupture and to identify some of the features associated with increased plaque vulnerability. In order this information to be obtained, other modalities such as optical coherence tomography, angioscopy, near infrared spectroscopy and intravascular magnetic resonance imaging have either been utilized or are under evaluation. The aim of this review article is to present the current utilities of IVUS in research and to discuss its advantages and disadvantages over the other imaging techniques.

Available only for authorised users

Hausmann D, Erbel R, Alibelli-Chemarin MJ, Boksch W, Caracciolo E, Cohn JM, Culp SC, Daniel WG, De Scheerder I, DiMario C, et al.: The safety of intracoronary ultrasound. A multicenter survey of 2207 examinations. Circulation 1995,91(3):623-30.CrossRefPubMed

Bourantas CV, Naka KK, Garg S, Thackray S, Papadopoulos D, Alamgir FM, Hoye A, Michalis LK: Clinical indications for intravascular ultrasound imaging. Echocardiography 2010,27(10):1282-90. 10.1111/j.1540-8175.2010.01259.xCrossRefPubMed

Mehta SK, McCrary JR, Frutkin AD, Dolla WJ, Marso SP: Intravascular ultrasound radiofrequency analysis of coronary atherosclerosis: an emerging technology for the assessment of vulnerable plaque. Eur Heart J 2007,28(11):1283-8. 10.1093/eurheartj/ehm112CrossRefPubMed

Mallery JA, Tobis JM, Griffith J, Gessert J, McRae M, Moussabeck O, Bessen M, Moriuchi M, Henry WL: Assessment of normal and atherosclerotic arterial wall thickness with an intravascular ultrasound imaging catheter. Am Heart J 1990,119(6):1392-1400.3. 10.1016/S0002-8703(05)80190-5CrossRefPubMed

Nishimura RA, Edwards WD, Warnes CA, Reeder GS, Holmes DR Jr, Tajik AJ, Yock PG: Intravascular ultrasound imaging: in vitro validation and pathologic correlation. J Am Coll Cardiol 1990,16(1):145-54. 10.1016/0735-1097(90)90472-2CrossRefPubMed

Koning G, Dijkstra J, von Birgelen C, Tuinenburg JC, Brunette J, Tardif JC, Oemrawsingh PW, Sieling C, Melsa S, Reiber JH: Advanced contour detection for three-dimensional intracoronary ultrasound: a validation-in vitro and in vivo. Int J Cardiovasc Imaging 2002,18(4):235-48. 10.1023/A:1015551920382CrossRefPubMed

Bourantas CV, Plissiti ME, Fotiadis DI, Protopappas VC, Mpozios GV, Katsouras CS, Kourtis IC, Rees MR, Michalis LK: In vivo validation of a novel semi-automated method for border detection in intravascular ultrasound images. Br J Radiol 2005,78(926):122-9. 10.1259/bjr/30866348CrossRefPubMed

Bruining N, Verheye S, Knaapen M, Somers P, Roelandt JR, Regar E, Heller I, de Winter S, Ligthart J, Van Langenhove G, de Feijter PJ, Serruys PW, Hamers R: Three-dimensional and quantitative analysis of atherosclerotic plaque composition by automated differential echogenicity. Catheter Cardiovasc Interv 2007,70(7):968-78. 10.1002/ccd.21310CrossRefPubMed

Potkin BN, Keren G, Mintz GS, Douek PC, Pichard AD, Satler LF, Kent KM, Leon MB: Arterial responses to balloon coronary angioplasty: an intravascular ultrasound study. J Am Coll Cardiol 1992,20(4):942-51. 10.1016/0735-1097(92)90197-UCrossRefPubMed

10.

Mintz GS, Popma JJ, Pichard AD, Kent KM, Satler LF, Wong C, Hong MK, Kovach JA, Leon MB: Arterial remodeling after coronary angioplasty: a serial intravascular ultrasound study. Circulation 1996,94(1):35-43.CrossRefPubMed

11.

Serruys PW, Luijten HE, Beatt KJ, Geuskens R, de Feyter PJ, van den Brand M, Reiber JH, ten Katen HJ, van Es GA, Hugenholtz PG: Incidence of restenosis after successful coronary angioplasty: a time-related phenomenon. A quantitative angiographic study in 342 consecutive patients at 1, 2, 3, and 4 months. Circulation 1988,77(2):361-71.CrossRefPubMed

12.

Stone GW, Hodgson JM, St Goar FG, Frey A, Mudra H, Sheehan H, Linnemeier TJ: Improved procedural results of coronary angioplasty with intravascular ultrasound-guided balloon sizing: the CLOUT Pilot Trial. Clinical Outcomes With Ultrasound Trial (CLOUT) Investigators. Circulation 1997,95(8):2044-52.CrossRefPubMed

13.

Berry C, L'Allier PL, Gregoire J, Lesperance J, Levesque S, Ibrahim R, Tardif JC: Comparison of intravascular ultrasound and quantitative coronary angiography for the assessment of coronary artery disease progression. Circulation 2007,115(14):1851-7. 10.1161/CIRCULATIONAHA.106.655654CrossRefPubMed

14.

Bose D, von Birgelen C, Erbel R: Intravascular ultrasound for the evaluation of therapies targeting coronary atherosclerosis. J Am Coll Cardiol 2007,49(9):925-32. 10.1016/j.jacc.2006.08.067CrossRefPubMed

15.

Garcia-Garcia HM, Costa MA, Serruys PW: Imaging of coronary atherosclerosis: intravascular ultrasound. Eur Heart J 2010,31(20):2456-69. 10.1093/eurheartj/ehq280CrossRefPubMed

16.

Nissen SE, Nicholls SJ, Sipahi I, Libby P, Raichlen JS, Ballantyne CM, Davignon J, Erbel R, Fruchart JC, Tardif JC, Schoenhagen P, Crowe T, Cain V, Wolski K, Goormastic M, Tuzcu EM: Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006,295(13):1556-65. 10.1001/jama.295.13.jpc60002CrossRefPubMed

17.

Nissen SE, Tuzcu EM, Schoenhagen P, Brown BG, Ganz P, Vogel RA, Crowe T, Howard G, Cooper CJ, Brodie B, Grines CL, DeMaria AN, REVERSAL Investigators: Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. JAMA 2004,291(9):1071-80. 10.1001/jama.291.9.1071CrossRefPubMed

18.

Okazaki S, Yokoyama T, Miyauchi K, Shimada K, Kurata T, Sato H, Daida H: Early statin treatment in patients with acute coronary syndrome: demonstration of the beneficial effect on atherosclerotic lesions by serial volumetric intravascular ultrasound analysis during half a year after coronary event: the ESTABLISH Study. Circulation 2004,110(9):1061-8. 10.1161/01.CIR.0000140261.58966.A4CrossRefPubMed

19.

Gerstein HC, Ratner RE, Cannon CP, Serruys PW, Garcia-Garcia HM, van Es GA, Kolatkar NS, Kravitz BG, Miller DM, Huang C, Fitzgerald PJ, Nesto RW: Effect of rosiglitazone on progression of coronary atherosclerosis in patients with type 2 diabetes mellitus and coronary artery disease: the assessment on the prevention of progression by rosiglitazone on atherosclerosis in diabetes patients with cardiovascular history trial. Circulation 2010,121(10):1176-87. 10.1161/CIRCULATIONAHA.109.881003CrossRefPubMed

20.

Nissen SE, Nicholls SJ, Wolski K, Nesto R, Kupfer S, Perez A, Jure H, De Larochelliere R, Staniloae CS, Mavromatis K, Saw J, Hu B, Lincoff AM, Tuzcu EM: Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. JAMA 2008,299(13):1561-73. 10.1001/jama.299.13.1561CrossRefPubMed

21.

Nissen SE, Tuzcu EM, Libby P, Thompson PD, Ghali M, Garza D, Berman L, Shi H, Buebendorf E, Topol EJ: Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial. JAMA 2004,292(18):2217-25. 10.1001/jama.292.18.2217CrossRefPubMed

22.

Rodriguez-Granillo GA, Vos J, Bruining N, Garcia-Garcia HM, de Winter S, Ligthart JM, Deckers JW, Bertrand M, Simoons ML, Ferrari R, Fox KM, Remme W, De Feyter PJ: Long-term effect of perindopril on coronary atherosclerosis progression (from the perindopril's prospective effect on coronary atherosclerosis by angiography and intravascular ultrasound evaluation [PERSPECTIVE] study). Am J Cardiol 2007,100(2):159-63. 10.1016/j.amjcard.2007.02.073CrossRefPubMed

23.

Tardif JC, Grégoire J, L'Allier PL, Ibrahim R, Lespérance J, Heinonen TM, Kouz S, Berry C, Basser R, Lavoie MA, Guertin MC, Rodés-Cabau J: Effect of rHDL on Atherosclerosis-Safety and Efficacy (ERASE) Investigators (2007): Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial. JAMA 2007,297(15):1675-82. 10.1001/jama.297.15.jpc70004CrossRefPubMed

24.

Serruys PW, Garcia-Garcia HM, Buszman P, Erne P, Verheye S, Aschermann M, Duckers H, Bleie O, Dudek D, Botker HE, von Birgelen C, D'Amico D, Hutchinson T, Zambanini A, Mastik F, van Es GA, van der Steen AF, Vince DG, Ganz P, Hamm CW, Wijns W, Zalewski A: Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation 2008,118(11):1172-82. 10.1161/CIRCULATIONAHA.108.771899CrossRefPubMed

25.

Nissen SE, Tuzcu EM, Brewer HB, Sipahi I, Nicholls SJ, Ganz P, Schoenhagen P, Waters DD, Pepine CJ, Crowe TD, Davidson MH, Deanfield JE, Wisniewski LM, Hanyok JJ, Kassalow LM: Effect of ACAT inhibition on the progression of coronary atherosclerosis. N Engl J Med 2006,354(12):1253-63. 10.1056/NEJMoa054699CrossRefPubMed

26.

Hassani SE, Mintz GS, Fong HS, Kim SW, Xue Z, Pichard AD, Satler LF, Kent KM, Suddath WO, Waksman R, Weissman NJ: Negative remodeling and calcified plaque in octogenarians with acute myocardial infarction: an intravascular ultrasound analysis. J Am Coll Cardiol 2006,47(12):2413-9. 10.1016/j.jacc.2005.11.091CrossRefPubMed

27.

Nakamura M, Nishikawa H, Mukai S, Setsuda M, Nakajima K, Tamada H, Suzuki H, Ohnishi T, Kakuta Y, Nakano T, Yeung AC: Impact of coronary artery remodeling on clinical presentation of coronary artery disease: an intravascular ultrasound study. J Am Coll Cardiol 2001,37(1):63-9. 10.1016/S0735-1097(00)01097-4CrossRefPubMed

28.

Brezinski ME: Optical coherence tomography for identifying unstable coronary plaque. Int J Cardiol 2006,107(2):154-65. 10.1016/j.ijcard.2005.07.066CrossRefPubMed

29.

Kawasaki M, Takatsu H, Noda T, Sano K, Ito Y, Hayakawa K, Tsuchiya K, Arai M, Nishigaki K, Takemura G, Minatoguchi S, Fujiwara T, Fujiwara H: In vivo quantitative tissue characterization of human coronary arterial plaques by use of integrated backscatter intravascular ultrasound and comparison with angioscopic findings. Circulation 2002,105(21):2487-92. 10.1161/01.CIR.0000017200.47342.10CrossRefPubMed

30.

Hara H, Tsunoda T, Nemoto N, Yokouchi I, Yamamoto M, Ono T, Moroi M, Suzuki M, Sugi K, Nakamura M: Distribution of ultrasonic radiofrequency signal amplitude detects lipids in atherosclerotic plaque of coronary arteries: an ex-vivo study. Cardiovasc Ultrasound 2008, 6: 18. 10.1186/1476-7120-6-18CrossRefPubMedPubMedCentral

31.

Sano K, Kawasaki M, Okubo M, Yokoyama H, Ito Y, Murata I, Kawai T, Tsuchiya K, Nishigaki K, Takemura G, Minatoguchi S, Zhou X, Fujita H, Fujiwara H: In vivo quantitative tissue characterization of angiographically normal coronary lesions and the relation with risk factors: a study using integrated backscatter intravascular ultrasound. Circ J 2005,69(5):543-9. 10.1253/circj.69.543CrossRefPubMed

32.

Valgimigli M, Rodriguez-Granillo GA, Garcia-Garcia HM, Malagutti P, Regar E, de Jaegere P, de Feyter P, Serruys PW: Distance from the ostium as an independent determinant of coronary plaque composition in vivo: an intravascular ultrasound study based radiofrequency data analysis in humans. Eur Heart J 2006,27(6):655-63. 10.1093/eurheartj/ehi716CrossRefPubMed

33.

Hong MK, Park DW, Lee CW, Lee SW, Kim YH, Kang DH, Song JK, Kim JJ, Park SW, Park SJ: Effects of statin treatments on coronary plaques assessed by volumetric virtual histology intravascular ultrasound analysis. JACC Cardiovasc Interv 2009,2(7):679-88. 10.1016/j.jcin.2009.03.015CrossRefPubMed

34.

Kubo T, Maehara A, Mintz GS, Doi H, Tsujita K, Choi SY, Katoh O, Nasu K, Koenig A, Pieper M, Rogers JH, Wijns W, Bose D, Margolis MP, Moses JW, Stone GW, Leon MB: The dynamic nature of coronary artery lesion morphology assessed by serial virtual histology intravascular ultrasound tissue characterization. J Am Coll Cardiol 2010,55(15):1590-7. 10.1016/j.jacc.2009.07.078CrossRefPubMed

35.

Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Juhani Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W Jr, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT: From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation 2003,108(14):1664-72. 10.1161/01.CIR.0000087480.94275.97CrossRefPubMed

36.

Kubo T, Imanishi T, Takarada S, Kuroi A, Ueno S, Yamano T, Tanimoto T, Matsuo Y, Masho T, Kitabata H, Tsuda K, Tomobuchi Y, Akasaka T: Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J Am Coll Cardiol 2007,50(10):933-9. 10.1016/j.jacc.2007.04.082CrossRefPubMed

37.

Schaar JA, De Korte CL, Mastik F, Strijder C, Pasterkamp G, Boersma E, Serruys PW, Van Der Steen AF: Characterizing vulnerable plaque features with intravascular elastography. Circulation 2003,108(21):2636-41. 10.1161/01.CIR.0000097067.96619.1FCrossRefPubMed

38.

de Korte CL, Sierevogel MJ, Mastik F, Strijder C, Schaar JA, Velema E, Pasterkamp G, Serruys PW, van der Steen AF: Identification of atherosclerotic plaque components with intravascular ultrasound elastography in vivo: a Yucatan pig study. Circulation 2002,105(14):1627-30. 10.1161/01.CIR.0000014988.66572.2ECrossRefPubMed

39.

Vavuranakis M, Kakadiaris IA, O'Malley SM, Papaioannou TG, Sanidas EA, Naghavi M, Carlier S, Tousoulis D, Stefanadis C: A new method for assessment of plaque vulnerability based on vasa vasorum imaging, by using contrast-enhanced intravascular ultrasound and differential image analysis. Int J Cardiol 2008,130(1):23-9. 10.1016/j.ijcard.2007.07.170CrossRefPubMed

40.

Jang IK, Bouma BE, Kang DH, Park SJ, Park SW, Seung KB, Choi KB, Shishkov M, Schlendorf K, Pomerantsev E, Houser SL, Aretz HT, Tearney GJ: Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound. J Am Coll Cardiol 2002,39(4):604-9. 10.1016/S0735-1097(01)01799-5CrossRefPubMed

41.

Yabushita H, Bouma BE, Houser SL, Aretz HT, Jang IK, Schlendorf KH, Kauffman CR, Shishkov M, Kang DH, Halpern EF, Tearney GJ: Characterization of human atherosclerosis by optical coherence tomography. Circulation 2002,106(13):1640-5. 10.1161/01.CIR.0000029927.92825.F6CrossRefPubMed

42.

Kume T, Akasaka T, Kawamoto T, Ogasawara Y, Watanabe N, Toyota E, Neishi Y, Sukmawan R, Sadahira Y, Yoshida K: Assessment of coronary arterial thrombus by optical coherence tomography. Am J Cardiol 2006,97(12):1713-7. 10.1016/j.amjcard.2006.01.031CrossRefPubMed

43.

Tearney GJ, Yabushita H, Houser SL, Aretz HT, Jang IK, Schlendorf KH, Kauffman CR, Shishkov M, Halpern EF, Bouma BE: Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography. Circulation 2003,107(1):113-9. 10.1161/01.CIR.0000044384.41037.43CrossRefPubMed

44.

Sawada T, Shite J, Garcia-Garcia HM, Shinke T, Watanabe S, Otake H, Matsumoto D, Tanino Y, Ogasawara D, Kawamori H, Kato H, Miyoshi N, Yokoyama M, Serruys PW, Hirata K: Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma. Eur Heart J 2008,29(9):1136-46. 10.1093/eurheartj/ehn132CrossRefPubMed

45.

Ueda Y, Ohtani T, Shimizu M, Hirayama A, Kodama K: Assessment of plaque vulnerability by angioscopic classification of plaque color. Am Heart J 2004,148(2):333-5. 10.1016/j.ahj.2004.03.047CrossRefPubMed

46.

Serruys PW, Degertekin M, Tanabe K, Abizaid A, Sousa JE, Colombo A, Guagliumi G, Wijns W, Lindeboom WK, Ligthart J, de Feyter PJ, Morice MC: Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial. Circulation 2002,106(7):798-803. 10.1161/01.CIR.0000025585.63486.59CrossRefPubMed

47.

Aoki J, Colombo A, Dudek D, Banning AP, Drzewiecki J, Zmudka K, Schiele F, Russell ME, Koglin J, Serruys PW: Peristent remodeling and neointimal suppression 2 years after polymer-based, paclitaxel-eluting stent implantation: insights from serial intravascular ultrasound analysis in the TAXUS II study. Circulation 2005,12(25):3876-83. 10.1161/CIRCULATIONAHA.105.558601CrossRef

48.

Onuma Y, Serruys P, den Heijer P, Joesoef KS, Duckers H, Regar E, Kukreja N, Tanimoto S, Garcia-Garcia HM, van Beusekom H, van der Giessen W, Nishide T: MAHOROBA, first-in-man study: 6-month results of a biodegradable polymer sustained release tacrolimus-eluting stent in de novo coronary stenoses. Eur Heart J 2009,30(12):1477-85. 10.1093/eurheartj/ehp127CrossRefPubMed

49.

Alfonso F, Perez-Vizcayno MJ, Hernandez R, Bethencourt A, Marti V, Lopez-Minguez JR, Angel J, Mantilla R, Moris C, Cequier A, Sabate M, Escaned J, Moreno R, Banuelos C, Suarez A, Macaya C: A randomized comparison of sirolimus-eluting stent with balloon angioplasty in patients with in-stent restenosis: results of the Restenosis Intrastent: Balloon Angioplasty Versus Elective Sirolimus-Eluting Stenting (RIBS-II) trial. J Am Coll Cardiol 2006,47(11):2152-60. 10.1016/j.jacc.2005.10.078CrossRefPubMed

50.

Schiele TM, Konig A, Rieber J, Erhard I, Leibig M, Theisen K, Siebert U, Klauss V: Sirolimus-eluting stent implantation and beta-irradiation for the treatment of in-stent restenotic lesions: comparison of underlying mechanisms of acute gain and late loss as assessed by volumetric intravascular ultrasound. Am Heart J 2005,150(2):351-7. 10.1016/j.ahj.2004.09.041CrossRefPubMed

51.

Fujii K, Carlier SG, Mintz GS, Yang YM, Moussa I, Weisz G, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB: Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study. J Am Coll Cardiol 2005,45(7):995-8. 10.1016/j.jacc.2004.12.066CrossRefPubMed

52.

Cook S, Wenaweser P, Togni M, Billinger M, Morger C, Seiler C, Vogel R, Hess O, Meier B, Windecker S: Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation. Circulation 2007,115(18):2426-34. 10.1161/CIRCULATIONAHA.106.658237CrossRefPubMed

53.

Biondi-Zoccai GG, Agostoni P, Sangiorgi GM, Airoldi F, Cosgrave J, Chieffo A, Barbagallo R, Tamburino C, Vittori G, Falchetti E, Margheri M, Briguori C, Remigi E, Iakovou I, Colombo A: Incidence, predictors, and outcomes of coronary dissections left untreated after drug-eluting stent implantation. Eur Heart J 2006,27(5):540-6. 10.1093/eurheartj/ehi618CrossRefPubMed

54.

Tanimoto S, Bruining N, van Domburg RT, Rotger D, Radeva P, Ligthart JM, Serruys PW: Late stent recoil of the bioabsorbable everolimus-eluting coronary stent and its relationship with plaque morphology. J Am Coll Cardiol 2008,52(20):1616-20. 10.1016/j.jacc.2008.08.024CrossRefPubMed

55.

Erbel R, Di Mario C, Bartunek J, Bonnier J, de Bruyne B, Eberli FR, Erne P, Haude M, Heublein B, Horrigan M, Ilsley C, Bose D, Koolen J, Luscher TF, Weissman N, Waksman R: Temporary scaffolding of coronary arteries with bioabsorbable magnesium stents: a prospective, non-randomised multicentre trial. Lancet 2007,369(9576):1869-75. 10.1016/S0140-6736(07)60853-8CrossRefPubMed

56.

Serruys PW, Ormiston JA, Onuma Y, Regar E, Gonzalo N, Garcia-Garcia HM, Nieman K, Bruining N, Dorange C, Miquel-Hebert K, Veldhof S, Webster M, Thuesen L, Dudek D: A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods. Lancet 2009,373(9667):897-910. 10.1016/S0140-6736(09)60325-1CrossRefPubMed

57.

Sarno G, Onuma Y, Garcia HM, Garg S, Regar E, Thuesen L, Dudek D, Veldhof S, Dorange C, Ormiston JA, Serruys PW: IVUS radiofrequency analysis in the evaluation of the polymeric struts of the bioabsorbable everolimus-eluting device during the bioabsorption process. Catheter Cardiovasc Interv 2010,75(6):914-8.PubMed

58.

Garcia-Garcia HM, Gonzalo N, Pawar R, Kukreja N, Dudek D, Thuesen L, Ormiston JA, Regar E, Serruys PW: Assessment of the absorption process following bioabsorbable everolimus-eluting stent implantation: temporal changes in strain values and tissue composition using intravascular ultrasound radiofrequency data analysis. A substudy of the ABSORB clinical trial. EuroIntervention 2009,4(4):443-8.CrossRefPubMed

59.

Barlis P, Regar E, Serruys PW, Dimopoulos K, van der Giessen WJ, van Geuns RJ, Ferrante G, Wandel S, Windecker S, van Es GA, Eerdmans P, Juni P, di Mario C: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study. Eur Heart J 2010,31(2):139-42. 10.1093/eurheartj/ehp480CrossRef

60.

Matsumoto D, Shite J, Shinke T, Otake H, Tanino Y, Ogasawara D, Sawada T, Paredes OL, Hirata K, Yokoyama M: Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography. Eur Heart J 2007,28(8):961-7. 10.1093/eurheartj/ehl413CrossRefPubMed

61.

Bouma BE, Tearney GJ, Yabushita H, Shishkov M, Kauffman CR, DeJoseph Gauthier D, MacNeill BD, Houser SL, Aretz HT, Halpern EF, Jang IK: Evaluation of intracoronary stenting by intravascular optical coherence tomography. Heart 2003,89(3):317-20. 10.1136/heart.89.3.317CrossRefPubMedPubMedCentral

62.

Takano M, Ohba T, Inami S, Seimiya K, Sakai S, Mizuno K: Angioscopic differences in neointimal coverage and in persistence of thrombus between sirolimus-eluting stents and bare metal stents after a 6-month implantation. Eur Heart J 2006,27(18):2189-95. 10.1093/eurheartj/ehl181CrossRefPubMed

63.

Bourantas CV, Kalatzis FG, Papafaklis MI, Fotiadis DI, Tweddel AC, Kourtis IC, Katsouras CS, Michalis LK: ANGIOCARE: an automated system for fast three-dimensional coronary reconstruction by integrating angiographic and intracoronary ultrasound data. Catheter Cardiovasc Interv 2008,72(2):166-75. 10.1002/ccd.21527CrossRefPubMed

64.

Slager CJ, Wentzel JJ, Schuurbiers JC, Oomen JA, Kloet J, Krams R, von Birgelen C, van der Giessen WJ, Serruys PW, de Feyter PJ: True 3-dimensional reconstruction of coronary arteries in patients by fusion of angiography and IVUS (ANGUS) and its quantitative validation. Circulation 2000,102(5):511-6.CrossRefPubMed

65.

Papafaklis MI, Bourantas CV, Theodorakis PE, Katsouras CS, Fotiadis DI, Michalis LK: Association of endothelial shear stress with plaque thickness in a real three-dimensional left main coronary artery bifurcation model. Int J Cardiol 2007,115(2):276-8. 10.1016/j.ijcard.2006.04.030CrossRefPubMed

66.

Stone PH, Coskun AU, Kinlay S, Popma JJ, Sonka M, Wahle A, Yeghiazarians Y, Maynard C, Kuntz RE, Feldman CL: Regions of low endothelial shear stress are the sites where coronary plaque progresses and vascular remodelling occurs in humans: an in vivo serial study. Eur Heart J 2007,28(6):705-10. 10.1093/eurheartj/ehl575CrossRefPubMed

67.

Papafaklis MI, Bourantas CV, Theodorakis PE, Katsouras CS, Fotiadis DI, Michalis LK: Relationship of shear stress with in-stent restenosis: bare metal stenting and the effect of brachytherapy. Int J Cardiol 2009,134(1):25-32. 10.1016/j.ijcard.2008.02.006CrossRefPubMed

68.

Chatzizisis YS, Jonas M, Coskun AU, Beigel R, Stone BV, Maynard C, Gerrity RG, Daley W, Rogers C, Edelman ER, Feldman CL, Stone PH: Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation 2008,117(8):993-1002. 10.1161/CIRCULATIONAHA.107.695254CrossRefPubMed

69.

Slager CJ, Wentzel JJ, Gijsen FJ, Thury A, van der Wal AC, Schaar JA, Serruys PW: The role of shear stress in the destabilization of vulnerable plaques and related therapeutic implications. Nat Clin Pract Cardiovasc Med 2005,2(9):456-64. 10.1038/ncpcardio0298CrossRefPubMed

70.

Garg S, Serruys PW, van der Ent M, Schultz C, Mastik F, van Soest G, van der Steen AF, Wilder MA, Muller JE, Regar E: First use in patients of a combined near infra-red spectroscopy and intra-vascular ultrasound catheter to identify composition and structure of coronary plaque. EuroIntervention 2010,5(6):755-6.CrossRefPubMed

71.

Larose E, Yeghiazarians Y, Libby P, Yucel EK, Aikawa M, Kacher DF, Aikawa E, Kinlay S, Schoen FJ, Selwyn AP, Ganz P: Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. Circulation 2005,112(15):2324-31. 10.1161/CIRCULATIONAHA.105.538942CrossRefPubMed

72.

Wilensky RL, Song HK, Ferrari VA: Role of magnetic resonance and intravascular magnetic resonance in the detection of vulnerable plaques. J Am Coll Cardiol 2006,47(8 Suppl):C48-56. 10.1016/j.jacc.2005.11.048CrossRefPubMed

73.

Wykrzykowska J, Lehman S, Williams G, Parker JA, Palmer MR, Varkey S, Kolodny G, Laham R: Imaging of inflamed and vulnerable plaque in coronary arteries with 18F-FDG PET/CT in patients with suppression of myocardial uptake using a low-carbohydrate, high-fat preparation. J Nucl Med 2009,50(4):563-8. 10.2967/jnumed.108.055616CrossRefPubMed

74.

Springer I, Dewey M: Comparison of multislice computed tomography with intravascular ultrasound for detection and characterization of coronary artery plaques: A systematic review. Eur J Radiol 71 2009, 71: 275-282. 10.1016/j.ejrad.2008.04.035CrossRef

75.

Schepis T, Marwan M, Pflederer T, Seltmann M, Ropers D, Daniel WG, Achenbach S: Quantification of non-calcified coronary atherosclerotic plaques with dual-source computed tomography: comparison with intravascular ultrasound. Heart 2010,96(8):610-5. 10.1136/hrt.2009.184226CrossRefPubMed

Title: Focus on the research utility of intravascular ultrasound - comparison with other invasive modalities
Authors: Christos V Bourantas
Scot Garg
Katerina K Naka
Attila Thury
Angela Hoye
Lampros K Michalis
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Cardiovascular Ultrasound / Issue 1/2011
Electronic ISSN: 1476-7120
DOI: https://doi.org/10.1186/1476-7120-9-2

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 1/2011

Pre-implant right ventricular function might be an important predictor of the response to cardiac resynchronization therapy

Repeated bedside echocardiography in children with respiratory failure

Lung ultrasound: a new tool for the cardiologist

Correlation between coronary artery disease severity, left ventricular mass index and carotid intima media thickness, assessed by radio-frequency

Doppler ultrasound in the measurement of pulse wave velocity: agreement with the Complior method

Assessment right atrial thrombus by real-time three dimensional transthoracic echocardiography in patient with dilated cardiomyopathy

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials