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Cardiovascular Ultrasound
Published in: Cardiovascular Ultrasound 1/2010

Open Access 01-12-2010 | Research

Early right ventricular systolic dysfunction in patients with systemic sclerosis without pulmonary hypertension: a Doppler Tissue and Speckle Tracking echocardiography study

Authors: Sebastian Schattke, Fabian Knebel, Andrea Grohmann, Henryk Dreger, Friederike Kmezik, Gabriela Riemekasten, Gert Baumann, Adrian C Borges

Published in: Cardiovascular Ultrasound | Issue 1/2010

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Abstract

Background

Isovolumetric acceleration (IVA) is a novel tissue Doppler parameter for the assessment of systolic function. The aim of this study was to evaluate IVA as an early parameter for the detection of right ventricular (RV) systolic dysfunction in patients with systemic sclerosis (SSc) without pulmonary hypertension.

Methods

22 patients and 22 gender- and age-matched healthy subjects underwent standard echocardiography with tissue Doppler imaging (TDI) and speckle tracking strain to assess RV function.

Results

Tricuspid annular plane systolic excursion (TAPSE) (23.2 ± 4.1 mm vs. 26.5 ± 2.9 mm, p < 0.006), peak myocardial systolic velocity (Sm) (11.6 ± 2.3 cm/s vs. 13.9 ± 2.7 cm/s, p = 0.005), isovolumetric contraction velocity (IVV) (10.3 ± 3 cm/s vs. 14.8 ± 3 cm/s, p < 0.001) and IVA (2.3 ± 0.4 m/s2 vs. 4.1 ± 0.8 m/s2, p < 0.001) were significant lower in the patient group. IVA was the best parameter to predict early systolic dysfunction with an area under the curve of 0.988.

Conclusion

IVA is a useful tool with high-predictive power to detect early right ventricular systolic impairment in patients with SSc and without pulmonary hypertension.
Appendix
Available only for authorised users
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Metadata
Title
Early right ventricular systolic dysfunction in patients with systemic sclerosis without pulmonary hypertension: a Doppler Tissue and Speckle Tracking echocardiography study
Authors
Sebastian Schattke
Fabian Knebel
Andrea Grohmann
Henryk Dreger
Friederike Kmezik
Gabriela Riemekasten
Gert Baumann
Adrian C Borges
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Cardiovascular Ultrasound / Issue 1/2010
Electronic ISSN: 1476-7120
DOI
https://doi.org/10.1186/1476-7120-8-3

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