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Cardiovascular Ultrasound
Published in: Cardiovascular Ultrasound 1/2012

Open Access 01-12-2012 | Research

A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease

Authors: Yu Wang, Tao Guo, Tie-kun Ma, Hong-yan Cai, Si-ming Tao, Yun-zhu Peng, Ping Yang, Ming-qing Chen, Yun Gu

Published in: Cardiovascular Ultrasound | Issue 1/2012

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Abstract

Background

Cardiac shock wave therapy (CSWT) improves cardiac function in patients with severe coronary artery disease (CAD). We aimed to evaluate the clinical outcomes of a new CSWT treatment regimen.

Methods

The 55 patients with severe CAD were randomly divided into 3 treatment groups. The control group (n = 14) received only medical therapy. In group A ( n = 20), CSWT was performed 3 times within 3 months. In group B ( n = 21), patients underwent 3 CSWT sessions/week, and 9 treatment sessions were completed within 1 month. Primary outcome measurement was 6-minute walk test (6MWT). Other measurements were also evaluated.

Results

The 6MWT, CCS grading of angina, dosage of nitroglycerin, NYHA classification, and SAQ scores were improved in group A and B compared to control group.

Conclusions

A CSWT protocol with 1 month treatment duration showed similar therapeutic efficacy compared to a protocol of 3 months duration.

Clinical trial registry

We have registered on ClinicalTrials.gov, the protocol ID is CSWT IN CHINA.
Appendix
Available only for authorised users
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Metadata
Title
A modified regimen of extracorporeal cardiac shock wave therapy for treatment of coronary artery disease
Authors
Yu Wang
Tao Guo
Tie-kun Ma
Hong-yan Cai
Si-ming Tao
Yun-zhu Peng
Ping Yang
Ming-qing Chen
Yun Gu
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Cardiovascular Ultrasound / Issue 1/2012
Electronic ISSN: 1476-7120
DOI
https://doi.org/10.1186/1476-7120-10-35

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