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Published in: Molecular Cancer 1/2008

Open Access 01-12-2008 | Research

An integrative model for recurrence in ovarian cancer

Authors: Alexandros Laios, Sharon A O'Toole, Richard Flavin, Cara Martin, Martina Ring, Noreen Gleeson, Tom D'Arcy, Eamonn PJ McGuinness, Orla Sheils, Brian L Sheppard, John J O' Leary

Published in: Molecular Cancer | Issue 1/2008

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Excerpt

Ovarian cancer is one of the commonest cancers in women and the leading cause of death from gynaecological malignancy in the western world. About 205,000 cases of ovarian cancer are diagnosed worldwide each year [1]. It accounts for 3% of female cancers in Ireland with over 350 new cases each year [2]. Marked heterogeneity is a hallmark of the disease, not only in tumor histotype and grade but also in response to chemotherapy and overall prognosis [3]. Over 90% of cases arise from the surface epithelium. Serous adenocarcinomas are the commonest and account for 40%–50% of malignant neoplasms [4]. …
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Metadata
Title
An integrative model for recurrence in ovarian cancer
Authors
Alexandros Laios
Sharon A O'Toole
Richard Flavin
Cara Martin
Martina Ring
Noreen Gleeson
Tom D'Arcy
Eamonn PJ McGuinness
Orla Sheils
Brian L Sheppard
John J O' Leary
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Molecular Cancer / Issue 1/2008
Electronic ISSN: 1476-4598
DOI
https://doi.org/10.1186/1476-4598-7-8

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