Skip to main content
Top
Published in: Nutrition Journal 1/2012

Open Access 01-12-2012 | Research

Tea and coffee consumption in relation to vitamin D and calcium levels in Saudi adolescents

Authors: Abdulaziz Al-Othman, Sara Al-Musharaf, Nasser M Al-Daghri, Sobhy Yakout, Khalid M Alkharfy, Yousef Al-Saleh, Omar S Al-Attas, Majed S Alokail, Osama Moharram, Shaun Sabico, Sudhesh Kumar, George P Chrousos

Published in: Nutrition Journal | Issue 1/2012

Login to get access

Abstract

Background

Coffee and tea consumption was hypothesized to interact with variants of vitamin D-receptor polymorphisms, but limited evidence exists. Here we determine for the first time whether increased coffee and tea consumption affects circulating levels of 25-hydroxyvitamin D in a cohort of Saudi adolescents.

Methods

A total of 330 randomly selected Saudi adolescents were included. Anthropometrics were recorded and fasting blood samples were analyzed for routine analysis of fasting glucose, lipid levels, calcium, albumin and phosphorous. Frequency of coffee and tea intake was noted. 25-hydroxyvitamin D levels were measured using enzyme-linked immunosorbent assays.

Results

Improved lipid profiles were observed in both boys and girls, as demonstrated by increased levels of HDL-cholesterol, even after controlling for age and BMI, among those consuming 9–12 cups of coffee/week. Vitamin D levels were significantly highest among those consuming 9–12 cups of tea/week in all subjects (p-value 0.009) independent of age, gender, BMI, physical activity and sun exposure.

Conclusion

This study suggests a link between tea consumption and vitamin D levels in a cohort of Saudi adolescents, independent of age, BMI, gender, physical activity and sun exposure. These findings should be confirmed prospectively.
Appendix
Available only for authorised users
Literature
2.
go back to reference Butt MS, Sultan MT: Coffee and its consumption: Benefits and risks. Crit Rev Food Sci Nutr. 2011, 51: 363-373. 10.1080/10408390903586412.CrossRefPubMed Butt MS, Sultan MT: Coffee and its consumption: Benefits and risks. Crit Rev Food Sci Nutr. 2011, 51: 363-373. 10.1080/10408390903586412.CrossRefPubMed
3.
go back to reference Spiller MA: The chemical components of coffee. Caffeine. 1998, Boca Raton: CRC Press, 97-161. Spiller MA: The chemical components of coffee. Caffeine. 1998, Boca Raton: CRC Press, 97-161.
4.
go back to reference Castellanos FX, Rapoport JL: Effects of caffeine on development and behavior in infancy and childhood: a review of the published literature. Food Chem Toxicol. 2002, 40: 1235-1242. 10.1016/S0278-6915(02)00097-2.CrossRefPubMed Castellanos FX, Rapoport JL: Effects of caffeine on development and behavior in infancy and childhood: a review of the published literature. Food Chem Toxicol. 2002, 40: 1235-1242. 10.1016/S0278-6915(02)00097-2.CrossRefPubMed
6.
go back to reference Hasling C, Sondergaard K, Charles P, Mosekilde L: Calcium metabolism in postmenopausal osteoporotic women is determined by dietary calcium and coffee intake. J Nutr. 1992, 122: 1119-1126.PubMed Hasling C, Sondergaard K, Charles P, Mosekilde L: Calcium metabolism in postmenopausal osteoporotic women is determined by dietary calcium and coffee intake. J Nutr. 1992, 122: 1119-1126.PubMed
7.
go back to reference Rapuri PB, Gallagher JC, Kinyamu HK, Ryschon KL: Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Am J Clin Nutr. 2001, 74: 694-700.PubMed Rapuri PB, Gallagher JC, Kinyamu HK, Ryschon KL: Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Am J Clin Nutr. 2001, 74: 694-700.PubMed
8.
go back to reference Hannan MT, Felson DT, Dawson-Hughes B, Tucker TL, Cupples LA, Wilson PW, Kiel DP: Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res. 2000, 15: 710-720.CrossRefPubMed Hannan MT, Felson DT, Dawson-Hughes B, Tucker TL, Cupples LA, Wilson PW, Kiel DP: Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res. 2000, 15: 710-720.CrossRefPubMed
9.
go back to reference Izuora K, Twombly JG, Whitford GM, Demertzis J, Pacifici R, Whyte MP: Skeletal fluorosis from brewed tea. J Clin Endocrinol Metab. 2011, 96: 2318-2324. 10.1210/jc.2010-2891.CrossRefPubMed Izuora K, Twombly JG, Whitford GM, Demertzis J, Pacifici R, Whyte MP: Skeletal fluorosis from brewed tea. J Clin Endocrinol Metab. 2011, 96: 2318-2324. 10.1210/jc.2010-2891.CrossRefPubMed
10.
11.
go back to reference Heaney RP: Effects of caffeine on bone and the calcium economy. Food Chem Toxicol. 2002, 40: 1263-1270. 10.1016/S0278-6915(02)00094-7.CrossRefPubMed Heaney RP: Effects of caffeine on bone and the calcium economy. Food Chem Toxicol. 2002, 40: 1263-1270. 10.1016/S0278-6915(02)00094-7.CrossRefPubMed
12.
go back to reference Heaney RP, Recker RR: Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. J Lab Clin Med. 1982, 99: 46-55.PubMed Heaney RP, Recker RR: Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. J Lab Clin Med. 1982, 99: 46-55.PubMed
13.
go back to reference Massey LK, Whitling SJ: Caffeine, urinary calcium, calcium metabolism and bone. J Nutr. 1993, 123: 1611-1614.PubMed Massey LK, Whitling SJ: Caffeine, urinary calcium, calcium metabolism and bone. J Nutr. 1993, 123: 1611-1614.PubMed
14.
go back to reference Kreiger N, Gross A, Hunter G: Dietary factors and fracture in postmenopausal women: a case–control study. Int J Epidemiol. 1992, 21: 953-958. 10.1093/ije/21.5.953.CrossRefPubMed Kreiger N, Gross A, Hunter G: Dietary factors and fracture in postmenopausal women: a case–control study. Int J Epidemiol. 1992, 21: 953-958. 10.1093/ije/21.5.953.CrossRefPubMed
15.
go back to reference Huopio J, Kroger H, Honkanen R, Saarikoski S, Alhava E: Risk factors for perimenopausal fractures: a prospective study. Osteoporos Int. 2000, 11: 219-227. 10.1007/s001980050284.CrossRefPubMed Huopio J, Kroger H, Honkanen R, Saarikoski S, Alhava E: Risk factors for perimenopausal fractures: a prospective study. Osteoporos Int. 2000, 11: 219-227. 10.1007/s001980050284.CrossRefPubMed
16.
go back to reference Gong G, Stern HS, Cheng SC, Fong N, Mordeson J, Deng HW, Recker RR: The association of bone mineral density with vitamin D receptor gene polymorphisms. Osteoporos Int. 1999, 9: 55-84. 10.1007/s001980050116.CrossRefPubMed Gong G, Stern HS, Cheng SC, Fong N, Mordeson J, Deng HW, Recker RR: The association of bone mineral density with vitamin D receptor gene polymorphisms. Osteoporos Int. 1999, 9: 55-84. 10.1007/s001980050116.CrossRefPubMed
17.
go back to reference Woods RJ, Fleet JC: The genetics of osteoporosis: vitamin D receptor polymorphisms. Annu Rev Nutr. 1998, 18: 233-258. 10.1146/annurev.nutr.18.1.233.CrossRef Woods RJ, Fleet JC: The genetics of osteoporosis: vitamin D receptor polymorphisms. Annu Rev Nutr. 1998, 18: 233-258. 10.1146/annurev.nutr.18.1.233.CrossRef
18.
go back to reference Rapuri PB, Gallagher JC, Nawaz Z: Caffeine decreases vitamin D receptor protein expression and 1,25(OH)2D3 stimulated alkaline phosphatase activity in human osteoblast cells. J Steroid Biochem Mol Biol. 2007, 103: 368-371. 10.1016/j.jsbmb.2006.12.037.CrossRefPubMed Rapuri PB, Gallagher JC, Nawaz Z: Caffeine decreases vitamin D receptor protein expression and 1,25(OH)2D3 stimulated alkaline phosphatase activity in human osteoblast cells. J Steroid Biochem Mol Biol. 2007, 103: 368-371. 10.1016/j.jsbmb.2006.12.037.CrossRefPubMed
19.
go back to reference Barone JJ, Roberts HR: Caffeine consumption. Food Chem Toxicol. 1996, 34: 119-129. 10.1016/0278-6915(95)00093-3.CrossRefPubMed Barone JJ, Roberts HR: Caffeine consumption. Food Chem Toxicol. 1996, 34: 119-129. 10.1016/0278-6915(95)00093-3.CrossRefPubMed
21.
go back to reference Ullrich D, Compagnone D, Munch B, Brandes A, Hille H, Bircher J: Urinary caffeine metabolites in man. Age-dependent changes and pattern in various clinical situations. Eur J Clin Pharmacol. 1992, 43: 167-172. 10.1007/BF01740665.CrossRefPubMed Ullrich D, Compagnone D, Munch B, Brandes A, Hille H, Bircher J: Urinary caffeine metabolites in man. Age-dependent changes and pattern in various clinical situations. Eur J Clin Pharmacol. 1992, 43: 167-172. 10.1007/BF01740665.CrossRefPubMed
22.
go back to reference Taft JL, French M, Danks JA, Larkins RG: Opposing actions of methylxanthines and dibutyryl cyclic AMP on 1,25 dihydroxyvitamin D3 production and calcium fluxes in isolated chick renal tubules. Biochem Biphys Res Commun. 1984, 121: 355-363. 10.1016/0006-291X(84)90730-7.CrossRef Taft JL, French M, Danks JA, Larkins RG: Opposing actions of methylxanthines and dibutyryl cyclic AMP on 1,25 dihydroxyvitamin D3 production and calcium fluxes in isolated chick renal tubules. Biochem Biphys Res Commun. 1984, 121: 355-363. 10.1016/0006-291X(84)90730-7.CrossRef
23.
go back to reference Jorde R, Sundsfjord J, Bonaa KH: Determinants of serum calcium in men and women. The Tromso Study. Eur J Epidemiol. 2001, 17: 1117-1123. 10.1023/A:1021272831251.CrossRefPubMed Jorde R, Sundsfjord J, Bonaa KH: Determinants of serum calcium in men and women. The Tromso Study. Eur J Epidemiol. 2001, 17: 1117-1123. 10.1023/A:1021272831251.CrossRefPubMed
24.
go back to reference Tagliabue A, Terracina D, Cena H, Turconi G, Lanzola E, Montomolli C: Coffee induced thermogenesis and skin temperature. Int J Obes Relat Metab Disord. 1994, 18: 537-541.PubMed Tagliabue A, Terracina D, Cena H, Turconi G, Lanzola E, Montomolli C: Coffee induced thermogenesis and skin temperature. Int J Obes Relat Metab Disord. 1994, 18: 537-541.PubMed
25.
go back to reference Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS: Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989, 49: 44-50.PubMed Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS: Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989, 49: 44-50.PubMed
26.
go back to reference Graham TE: Caffeine and exercise: metabolism, endurance and performance. Sports Med. 2001, 31: 785-807. 10.2165/00007256-200131110-00002.CrossRefPubMed Graham TE: Caffeine and exercise: metabolism, endurance and performance. Sports Med. 2001, 31: 785-807. 10.2165/00007256-200131110-00002.CrossRefPubMed
27.
go back to reference Astrup A: Thermogenic drugs as a strategy for treatment of obesity. Endocrine. 2000, 13: 207-212. 10.1385/ENDO:13:2:207.CrossRefPubMed Astrup A: Thermogenic drugs as a strategy for treatment of obesity. Endocrine. 2000, 13: 207-212. 10.1385/ENDO:13:2:207.CrossRefPubMed
28.
go back to reference Ryu S, Choi SK, Joung SS, Suh H, Cha YS, Lee S, Lim K: Caffeine and lipolytic food component increases endurance performance in rats and athletes. J Nutr Sci Vitaminol. 2001, 47: 139-146. 10.3177/jnsv.47.139.CrossRefPubMed Ryu S, Choi SK, Joung SS, Suh H, Cha YS, Lee S, Lim K: Caffeine and lipolytic food component increases endurance performance in rats and athletes. J Nutr Sci Vitaminol. 2001, 47: 139-146. 10.3177/jnsv.47.139.CrossRefPubMed
29.
go back to reference Keijzers GB, De Galan BE, Tack CJ, Smits P: Caffeine can decrease insulin sensitivity in humans. Diabetes Care. 2002, 25: 364-369. 10.2337/diacare.25.2.364.CrossRefPubMed Keijzers GB, De Galan BE, Tack CJ, Smits P: Caffeine can decrease insulin sensitivity in humans. Diabetes Care. 2002, 25: 364-369. 10.2337/diacare.25.2.364.CrossRefPubMed
30.
go back to reference Kamycheva E, Joakimsen RM, Jorde R: Intakes of calcium and vitmin D predict body mass index in the population of Northern Norway. J Nutr. 2003, 133: 102-106.PubMed Kamycheva E, Joakimsen RM, Jorde R: Intakes of calcium and vitmin D predict body mass index in the population of Northern Norway. J Nutr. 2003, 133: 102-106.PubMed
31.
go back to reference Riedt CS, Cifuentes M, Stahl T, Chowdhury HA, Schlussel Y, Shapses SA: Overweight postmenopausal women lose bone with moderate weight reduction and 1 g/day calcium intake. J Bone Miner Res. 2005, 20: 455-463.CrossRefPubMed Riedt CS, Cifuentes M, Stahl T, Chowdhury HA, Schlussel Y, Shapses SA: Overweight postmenopausal women lose bone with moderate weight reduction and 1 g/day calcium intake. J Bone Miner Res. 2005, 20: 455-463.CrossRefPubMed
32.
go back to reference Tzotas T, Papadopoulou FG, Tsiomaoos K, Karras S, Gastaris K, Perros P, Krassas GE: Rising serum 25-hydroxy-vitamin D levels after weight loss in obese women correlate with improvement in insulin resistance. J Clin Endocrinol Metab. 2010, 95: 4251-4257. 10.1210/jc.2010-0757.CrossRef Tzotas T, Papadopoulou FG, Tsiomaoos K, Karras S, Gastaris K, Perros P, Krassas GE: Rising serum 25-hydroxy-vitamin D levels after weight loss in obese women correlate with improvement in insulin resistance. J Clin Endocrinol Metab. 2010, 95: 4251-4257. 10.1210/jc.2010-0757.CrossRef
33.
go back to reference Zittermann A, Frisch S, Berthold HK, Gotting C, Kuhn J, Kleesiek K, Stehle P, Koertke H, Koerfer R: Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers. Am J Clin Nutr. 2009, 89: 1321-1327. 10.3945/ajcn.2008.27004.CrossRefPubMed Zittermann A, Frisch S, Berthold HK, Gotting C, Kuhn J, Kleesiek K, Stehle P, Koertke H, Koerfer R: Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers. Am J Clin Nutr. 2009, 89: 1321-1327. 10.3945/ajcn.2008.27004.CrossRefPubMed
34.
go back to reference Higdon JV, Frei B: Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr. 2006, 46: 101-123. 10.1080/10408390500400009.CrossRefPubMed Higdon JV, Frei B: Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr. 2006, 46: 101-123. 10.1080/10408390500400009.CrossRefPubMed
35.
go back to reference Schneider C, Serge T: Green tea: potential health benefits. Am Fam Physician. 2009, 79: 591-594.PubMed Schneider C, Serge T: Green tea: potential health benefits. Am Fam Physician. 2009, 79: 591-594.PubMed
36.
go back to reference Greenberg JA, Axen KV, Schnoll R, Boozer CN: Coffee, tea and diabetes: the role of weight loss and caffeine. Int J Obes (Lond). 2005, 29: 1121-1129. 10.1038/sj.ijo.0802999.CrossRef Greenberg JA, Axen KV, Schnoll R, Boozer CN: Coffee, tea and diabetes: the role of weight loss and caffeine. Int J Obes (Lond). 2005, 29: 1121-1129. 10.1038/sj.ijo.0802999.CrossRef
37.
go back to reference He RR, Chen L, Lin BH, Matsui Y, Yao XS, Kurihara H: Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects. Chin J Integr Med. 2009, 15: 34-41. 10.1007/s11655-009-0034-8.CrossRefPubMed He RR, Chen L, Lin BH, Matsui Y, Yao XS, Kurihara H: Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects. Chin J Integr Med. 2009, 15: 34-41. 10.1007/s11655-009-0034-8.CrossRefPubMed
38.
go back to reference Thom E: The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people. J Int Med Res. 2007, 35: 900-908.CrossRefPubMed Thom E: The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people. J Int Med Res. 2007, 35: 900-908.CrossRefPubMed
Metadata
Title
Tea and coffee consumption in relation to vitamin D and calcium levels in Saudi adolescents
Authors
Abdulaziz Al-Othman
Sara Al-Musharaf
Nasser M Al-Daghri
Sobhy Yakout
Khalid M Alkharfy
Yousef Al-Saleh
Omar S Al-Attas
Majed S Alokail
Osama Moharram
Shaun Sabico
Sudhesh Kumar
George P Chrousos
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Nutrition Journal / Issue 1/2012
Electronic ISSN: 1475-2891
DOI
https://doi.org/10.1186/1475-2891-11-56

Other articles of this Issue 1/2012

Nutrition Journal 1/2012 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine