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Published in: Malaria Journal 1/2010

Open Access 01-12-2010 | Research

Evaluation of selected South African ethnomedicinal plants as mosquito repellents against the Anopheles arabiensis mosquito in a rodent model

Authors: Rajendra Maharaj, Vinesh Maharaj, Marion Newmarch, Neil R Crouch, Niresh Bhagwandin, Peter I Folb, Pamisha Pillay, Reshma Gayaram

Published in: Malaria Journal | Issue 1/2010

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Abstract

Background

This study was initiated to establish whether any South African ethnomedicinal plants (indigenous or exotic), that have been reported to be used traditionally to repel or kill mosquitoes, exhibit effective mosquito repellent properties.

Methods

Extracts of a selection of South African taxa were tested for repellency properties in an applicable mosquito feeding-probing assay using unfed female Anopheles arabiensis.

Results

Although a water extract of the roots of Chenopodium opulifolium was found to be 97% as effective as DEET after 2 mins, time lag studies revealed a substantial reduction in efficacy (to 30%) within two hours.

Conclusions

None of the plant extracts investigated exhibited residual repellencies >60% after three hours.
Literature
2.
go back to reference Sharp BL: Anopheles merus Dönitz. Its biology in relation to malaria transmission in Natal. 1983, MSc, University of Witwatersrand, Johannesburg Sharp BL: Anopheles merus Dönitz. Its biology in relation to malaria transmission in Natal. 1983, MSc, University of Witwatersrand, Johannesburg
3.
go back to reference Mafong EA, Kaplan LA: Insect repellents: What really works?. Postgrad Med. 1997, 102 (63): 68-69. 74 Mafong EA, Kaplan LA: Insect repellents: What really works?. Postgrad Med. 1997, 102 (63): 68-69. 74
4.
go back to reference Koren G, Matsui D, Bailey B: DEET-based insect repellents: safety implications for children and pregnant and lactating women. Can Med Assoc J. 2003, 169: 209-212. Koren G, Matsui D, Bailey B: DEET-based insect repellents: safety implications for children and pregnant and lactating women. Can Med Assoc J. 2003, 169: 209-212.
5.
go back to reference Fradin MS: Mosquitoes and mosquito repellents: a clinician's guide. Ann Int Med. 1998, 128: 931-940.CrossRefPubMed Fradin MS: Mosquitoes and mosquito repellents: a clinician's guide. Ann Int Med. 1998, 128: 931-940.CrossRefPubMed
6.
go back to reference Clarkson C, Maharaj VJ, Crouch NR, Grace OM, Pillay P, Matsabisa MG, Bhgawandin N, Smith PJ, Folb PI: In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa. J Ethnopharmacol. 2004, 92: 177-191. 10.1016/j.jep.2004.02.011.CrossRefPubMed Clarkson C, Maharaj VJ, Crouch NR, Grace OM, Pillay P, Matsabisa MG, Bhgawandin N, Smith PJ, Folb PI: In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa. J Ethnopharmacol. 2004, 92: 177-191. 10.1016/j.jep.2004.02.011.CrossRefPubMed
7.
go back to reference Seyoum A, Kabiru EW, Lwande W, Killeen GF, Hassanali A, Knols BG: Repellency of live potted plants against Anopheles gambiae from human baits in semi-field experimental huts. Am J Trop Med Hyg. 2002, 67: 191-195.PubMed Seyoum A, Kabiru EW, Lwande W, Killeen GF, Hassanali A, Knols BG: Repellency of live potted plants against Anopheles gambiae from human baits in semi-field experimental huts. Am J Trop Med Hyg. 2002, 67: 191-195.PubMed
8.
go back to reference Seyoum A, Palsson K, Kung'a S, Kabiru EW, Lwande W, Killeen GF, Hassanali A, Knols BG: Traditional use of mosquito-repellent plants in western Kenya and their evaluation in semi-field experimental huts against Anopheles gambiae: ethnobotanical studies and application by thermal expulsion and direct burning. Trans R Soc Trop Med Hyg. 2002, 96: 225-231. 10.1016/S0035-9203(02)90084-2.CrossRefPubMed Seyoum A, Palsson K, Kung'a S, Kabiru EW, Lwande W, Killeen GF, Hassanali A, Knols BG: Traditional use of mosquito-repellent plants in western Kenya and their evaluation in semi-field experimental huts against Anopheles gambiae: ethnobotanical studies and application by thermal expulsion and direct burning. Trans R Soc Trop Med Hyg. 2002, 96: 225-231. 10.1016/S0035-9203(02)90084-2.CrossRefPubMed
9.
go back to reference Jaenson TG, Palsson K, Borg-Karlson AK: Evaluation of extracts and oils of tick-repellent plants from Sweden. Med Vet Entomol. 2005, 19: 345-352. 10.1111/j.1365-2915.2005.00578.x.CrossRefPubMed Jaenson TG, Palsson K, Borg-Karlson AK: Evaluation of extracts and oils of tick-repellent plants from Sweden. Med Vet Entomol. 2005, 19: 345-352. 10.1111/j.1365-2915.2005.00578.x.CrossRefPubMed
10.
go back to reference WHO,CTD/WHOPES/IC/96.1: Protocols for laboratory and field evaluation of Insecticides and Repellents 1996. WHO/HQ Geneva WHO,CTD/WHOPES/IC/96.1: Protocols for laboratory and field evaluation of Insecticides and Repellents 1996. WHO/HQ Geneva
11.
go back to reference Vahitha R, Venkatachalam MR, Murugan K, Jebanesan A: Larvicidal efficacy of Pavonia zeylanica L. and Acacia ferruginea D.C. against Culex quinquefasciatus Say. Biores Technol. 2002, 82: 203-204. 10.1016/S0960-8524(01)00175-4.CrossRef Vahitha R, Venkatachalam MR, Murugan K, Jebanesan A: Larvicidal efficacy of Pavonia zeylanica L. and Acacia ferruginea D.C. against Culex quinquefasciatus Say. Biores Technol. 2002, 82: 203-204. 10.1016/S0960-8524(01)00175-4.CrossRef
12.
go back to reference Yang YC, Lim MY, Lee HS: Emodin isolated from Cassia obtusifolia (Leguminosae) seed shows larvicidal activity against three mosquito species. J Agr Food Chem. 2003, 51: 7629-7631. 10.1021/jf034727t.CrossRef Yang YC, Lim MY, Lee HS: Emodin isolated from Cassia obtusifolia (Leguminosae) seed shows larvicidal activity against three mosquito species. J Agr Food Chem. 2003, 51: 7629-7631. 10.1021/jf034727t.CrossRef
13.
go back to reference Park BS, Choi WS, Kim JH, Kim KH, Lee SE: Monoterpenes from thyme (Thymus vulgaris) as potential mosquito repellents. J Am Mosq Control Assoc. 2005, 21: 80-83. 10.2987/8756-971X(2005)21[80:MFTTVA]2.0.CO;2.CrossRefPubMed Park BS, Choi WS, Kim JH, Kim KH, Lee SE: Monoterpenes from thyme (Thymus vulgaris) as potential mosquito repellents. J Am Mosq Control Assoc. 2005, 21: 80-83. 10.2987/8756-971X(2005)21[80:MFTTVA]2.0.CO;2.CrossRefPubMed
14.
go back to reference Rajkumar S, Jebanesan A: Mosquitocidal activity of octacosane from Moschosma polystachyum L. (Lamiaceae). J Ethnopharmacol. 2004, 90: 87-89. 10.1016/j.jep.2003.09.030.CrossRefPubMed Rajkumar S, Jebanesan A: Mosquitocidal activity of octacosane from Moschosma polystachyum L. (Lamiaceae). J Ethnopharmacol. 2004, 90: 87-89. 10.1016/j.jep.2003.09.030.CrossRefPubMed
15.
go back to reference Roark RC: Some promising insecticidal plants. Econom Bot. 1947, 1: 437-445.CrossRef Roark RC: Some promising insecticidal plants. Econom Bot. 1947, 1: 437-445.CrossRef
16.
go back to reference Tuetun B, Choochote W, Kanjanapothi D, Rattanachanpichai E, Chaithong U, Chaiwong P, Jitpakdi A, Tippawangkosol P, Riyong D, Pitasawat B: Repellent properties of celery, Apium graveolens L., compared with commercial repellents, against mosquitoes under laboratory and field conditions. Trop Med Int Health. 2005, 10: 1190-1198. 10.1111/j.1365-3156.2005.01500.x.CrossRefPubMed Tuetun B, Choochote W, Kanjanapothi D, Rattanachanpichai E, Chaithong U, Chaiwong P, Jitpakdi A, Tippawangkosol P, Riyong D, Pitasawat B: Repellent properties of celery, Apium graveolens L., compared with commercial repellents, against mosquitoes under laboratory and field conditions. Trop Med Int Health. 2005, 10: 1190-1198. 10.1111/j.1365-3156.2005.01500.x.CrossRefPubMed
17.
go back to reference Prajapati V, Tripathi AK, Aggarwal KK, Khanuja SP: Insecticidal, repellent and oviposition-deterrent activity of selected essential oils against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus. Biores Technol. 2005, 96: 1749-1757. 10.1016/j.biortech.2005.01.007.CrossRef Prajapati V, Tripathi AK, Aggarwal KK, Khanuja SP: Insecticidal, repellent and oviposition-deterrent activity of selected essential oils against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus. Biores Technol. 2005, 96: 1749-1757. 10.1016/j.biortech.2005.01.007.CrossRef
18.
go back to reference Barasa SS, Ndiege IO, Lwande W, Hassanali A: Repellent activities of stereoisomers of p-menthane-3,8-diols against Anopheles gambiae (Diptera: Culicidae). J Med Entomol. 2002, 39: 736-74. 10.1603/0022-2585-39.5.736.CrossRefPubMed Barasa SS, Ndiege IO, Lwande W, Hassanali A: Repellent activities of stereoisomers of p-menthane-3,8-diols against Anopheles gambiae (Diptera: Culicidae). J Med Entomol. 2002, 39: 736-74. 10.1603/0022-2585-39.5.736.CrossRefPubMed
19.
go back to reference Costantini C, Badolo A, Ilboudo-Sanogo E: Field evaluation of the efficacy and persistence of insect repellents DEET, IR3535, and KBR 3023 against Anopheles gambiae complex and other Afrotropical vector mosquitoes. Trans R Soc Trop Med Hyg. 2004, 98: 644-652.CrossRefPubMed Costantini C, Badolo A, Ilboudo-Sanogo E: Field evaluation of the efficacy and persistence of insect repellents DEET, IR3535, and KBR 3023 against Anopheles gambiae complex and other Afrotropical vector mosquitoes. Trans R Soc Trop Med Hyg. 2004, 98: 644-652.CrossRefPubMed
20.
go back to reference Jaenson TG, Palsson K, Borg-Karlson AK: Evaluation of extracts and oils of mosquito (Diptera: Culicidae) repellent plants from Sweden and Guinea-Bissau. J Med Entomol. 2006, 43: 113-119. 10.1603/0022-2585(2006)043[0113:EOEAOO]2.0.CO;2.CrossRefPubMed Jaenson TG, Palsson K, Borg-Karlson AK: Evaluation of extracts and oils of mosquito (Diptera: Culicidae) repellent plants from Sweden and Guinea-Bissau. J Med Entomol. 2006, 43: 113-119. 10.1603/0022-2585(2006)043[0113:EOEAOO]2.0.CO;2.CrossRefPubMed
Metadata
Title
Evaluation of selected South African ethnomedicinal plants as mosquito repellents against the Anopheles arabiensis mosquito in a rodent model
Authors
Rajendra Maharaj
Vinesh Maharaj
Marion Newmarch
Neil R Crouch
Niresh Bhagwandin
Peter I Folb
Pamisha Pillay
Reshma Gayaram
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2010
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-9-301

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