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Malaria Journal
Published in: Malaria Journal 1/2011

Open Access 01-12-2011 | Case report

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand

Authors: Marcus J Rijken, Machteld E Boel, Bruce Russell, Mallika Imwong, Mara L Leimanis, Aung Pyae Phyo, Atis Muehlenbachs, Niklas Lindegardh, Rose McGready, Laurent Rénia, Georges Snounou, Pratap Singhasivanon, François Nosten

Published in: Malaria Journal | Issue 1/2011

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Abstract

Chloroquine (CQ) resistant vivax malaria is spreading. In this case, Plasmodium vivax infections during pregnancy and in the postpartum period were not satisfactorily cleared by CQ, despite adequate drug concentrations. A growth restricted infant was delivered. Poor susceptibility to CQ was confirmed in-vitro and molecular genotyping was strongly suggestive of true recrudescence of P. vivax. This is the first clinically and laboratory confirmed case of two high-grade CQ resistant vivax parasite strains from Thailand.
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Metadata
Title
Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand
Authors
Marcus J Rijken
Machteld E Boel
Bruce Russell
Mallika Imwong
Mara L Leimanis
Aung Pyae Phyo
Atis Muehlenbachs
Niklas Lindegardh
Rose McGready
Laurent Rénia
Georges Snounou
Pratap Singhasivanon
François Nosten
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2011
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-10-113

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