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BMC Complementary Medicine and Therapies

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Open Access 01-12-2013 | Research article

Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification

Authors: Fidele Ntie-Kang, Lydia Likowo Lifongo, Luc Meva’a Mbaze, Nnange Ekwelle, Luc C Owono Owono, Eugene Megnassan, Philip N Judson, Wolfgang Sippl, Simon M N Efange

Published in: BMC Complementary Medicine and Therapies | Issue 1/2013

Abstract

Background

In Cameroon herbs are traditionally used to meet health care needs and plans are on the way to integrate traditional medicine in the health care system, even though the plans have not been put into action yet. The country however has a rich biodiversity, with ~8,620 plant species, some of which are commonly used in the treatment of several microbial infections and a range of diseases (malaria, trypanosomiasis, leishmaniasis, diabetes and tuberculosis).

Methods

Our survey consisted in collecting published data from the literature sources, mainly from PhD theses in Cameroonian university libraries and also using the author queries in major natural product and medicinal chemistry journals. The collected data includes plant sources, uses of plant material in traditional medicine, plant families, region of collection of plant material, isolated metabolites and type (e.g. flavonoid, terpenoid, etc.), measured biological activities of isolated compounds, and any comments on significance of isolated metabolites on the chemotaxonomic classification of the plant species. This data was compiled on a excel sheet and analysed.

Results

In this study, a literature survey led to the collection of data on 2,700 secondary metabolites, which have been previously isolated or derived from Cameroonian medicinal plants. This represents distinct phytochemicals derived from 312 plant species belonging to 67 plant families. The plant species are investigated in terms of chemical composition with respect to the various plant families. A correlation between the known biological activities of isolated compounds and the ethnobotanical uses of the plants is also attempted. Insight into future direction for natural product search within the Cameroonian forest and Savanna is provided.

Conclusions

It can be verified that a phytochemical search of active secondary metabolites, which is inspired by knowledge from the ethnobotanical uses of medicinal plants could be very vital in a drug discovery program from plant-derived bioactive compounds.

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1472-6882/13/147/prepub

Title: Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification
Authors: Fidele Ntie-Kang
Lydia Likowo Lifongo
Luc Meva’a Mbaze
Nnange Ekwelle
Luc C Owono Owono
Eugene Megnassan
Philip N Judson
Wolfgang Sippl
Simon M N Efange
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: BMC Complementary Medicine and Therapies / Issue 1/2013
Electronic ISSN: 2662-7671
DOI: https://doi.org/10.1186/1472-6882-13-147

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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