Skip to main content
Top
Published in: BMC Women's Health 1/2014

Open Access 01-12-2014 | Case report

A case of recurrent, bilateral ovarian mature teratoma in a young woman

Authors: Che-Fu Chang, Chen-Kuo Lin

Published in: BMC Women's Health | Issue 1/2014

Login to get access

Abstract

Background

Ovarian mature cystic teratomas are common, benign, pelvic tumors that are easily detected by pelvic ultrasonography. However, patients with recurrent teratomas are rarely noted, and cases of bilateral teratomas are even less common.

Case presentation

A young woman with a recurrent, right ovarian teratoma had previously undergone surgical removal 2 times. After the second surgery, she underwent regular out-patient follow-up, and no residual tumor was observed. However, 3 years after the second surgery, she developed recurrent, bilateral ovarian teratomas, in conjunction with elevated carbohydrate antigen-125 levels.

Conclusion

Routine checking of the contralateral ovary during the surgical procedure along with frequent postoperative pelvic sonography for both ovaries in the patient at high recurrence rich is necessary. Additionally, the features of that kind tumor may mislead the surgeon into performing more extensive surgery that might compromise the fertility of young patients.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kim MJ, Kim NY, Lee DY, Yoon BK, Choi D: Clinical characteristics of ovarian teratoma: age-focused retrospective analysis of 580 cases. Am J Obstet Gynecol. 2011, 205: e1-e32.CrossRef Kim MJ, Kim NY, Lee DY, Yoon BK, Choi D: Clinical characteristics of ovarian teratoma: age-focused retrospective analysis of 580 cases. Am J Obstet Gynecol. 2011, 205: e1-e32.CrossRef
2.
go back to reference Harding MJ, Paul J, Gillis CR, Kaye SB: Management of malignant teratoma: does referral to a specialist unit matter?. Lancet. 1993, 341: 999-1002. 10.1016/0140-6736(93)91082-W.CrossRefPubMed Harding MJ, Paul J, Gillis CR, Kaye SB: Management of malignant teratoma: does referral to a specialist unit matter?. Lancet. 1993, 341: 999-1002. 10.1016/0140-6736(93)91082-W.CrossRefPubMed
3.
go back to reference Alotaibi MO, Navarro OM: Imaging of ovarian teratomas in children: a 9-year review. Can Assoc Radiol J. 2010, 61: 23-28. 10.1016/j.carj.2009.07.001.CrossRefPubMed Alotaibi MO, Navarro OM: Imaging of ovarian teratomas in children: a 9-year review. Can Assoc Radiol J. 2010, 61: 23-28. 10.1016/j.carj.2009.07.001.CrossRefPubMed
4.
go back to reference Kahraman K, Cetinkaya SE, Kankaya D, Dunder I, Soylemez F: Squamous cell carcinoma arising from mature cystic teratoma of the ovary with synchronous endometrial adenocarcinoma. J Obstet Gynaecol Res. 2011, 37: 146-150.CrossRefPubMed Kahraman K, Cetinkaya SE, Kankaya D, Dunder I, Soylemez F: Squamous cell carcinoma arising from mature cystic teratoma of the ovary with synchronous endometrial adenocarcinoma. J Obstet Gynaecol Res. 2011, 37: 146-150.CrossRefPubMed
5.
go back to reference Ozgur T, Atik E, Silfeler DB, Toprak S: Mature cystic teratoma in our series with review of literature and retrospective analysis. Arch Gynecol Obstet. 2012, 285: 1099-1101. 10.1007/s00404-011-2171-8.CrossRefPubMed Ozgur T, Atik E, Silfeler DB, Toprak S: Mature cystic teratoma in our series with review of literature and retrospective analysis. Arch Gynecol Obstet. 2012, 285: 1099-1101. 10.1007/s00404-011-2171-8.CrossRefPubMed
6.
go back to reference Caspi B, Appelman Z, Rabinerson D, Zalel Y, Tulandi T, Shoham Z: The growth pattern of ovarian dermoid cysts: a prospective study in premenopausal and postmenopausal women. Fertil Steril. 1997, 68: 501-505. 10.1016/S0015-0282(97)00228-8.CrossRefPubMed Caspi B, Appelman Z, Rabinerson D, Zalel Y, Tulandi T, Shoham Z: The growth pattern of ovarian dermoid cysts: a prospective study in premenopausal and postmenopausal women. Fertil Steril. 1997, 68: 501-505. 10.1016/S0015-0282(97)00228-8.CrossRefPubMed
7.
go back to reference Pepe F, Panella M, Pepe G, Panella P, Pennisi F, Arikian S: Dermoid cysts of the ovary. Eur J Gynaecol Oncol. 1986, 7: 186-191.PubMed Pepe F, Panella M, Pepe G, Panella P, Pennisi F, Arikian S: Dermoid cysts of the ovary. Eur J Gynaecol Oncol. 1986, 7: 186-191.PubMed
8.
go back to reference Blackwell WJ, Dockerty MB, Masson JC: Dermoid cysts of the ovary: their clinical and pathologic significance. Am J Obstet Gynecol. 1946, 51: 151-172.CrossRefPubMed Blackwell WJ, Dockerty MB, Masson JC: Dermoid cysts of the ovary: their clinical and pathologic significance. Am J Obstet Gynecol. 1946, 51: 151-172.CrossRefPubMed
9.
go back to reference Comerci JT, Licciardi F, Bergh PA, Gregori C, Breen JL: Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. Obstet Gynecol. 1994, 84: 22-28.PubMed Comerci JT, Licciardi F, Bergh PA, Gregori C, Breen JL: Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. Obstet Gynecol. 1994, 84: 22-28.PubMed
10.
go back to reference Pfeifer SM, Gosman GG: Evaluation of adnexal masses in adolescents. Pediatr Clin North Am. 1999, 46: 573-592. 10.1016/S0031-3955(05)70138-3.CrossRefPubMed Pfeifer SM, Gosman GG: Evaluation of adnexal masses in adolescents. Pediatr Clin North Am. 1999, 46: 573-592. 10.1016/S0031-3955(05)70138-3.CrossRefPubMed
11.
go back to reference Al Jama FE, Al Ghamdi AA, Gasim T, Al Dakhiel SA, Rahman J, Rahman MS: Ovarian tumors in children and adolescents—a clinical study of 52 patients in a university hospital. J Pediatr Adolesc Gynecol. 2011, 24: 25-28. 10.1016/j.jpag.2010.06.005.CrossRefPubMed Al Jama FE, Al Ghamdi AA, Gasim T, Al Dakhiel SA, Rahman J, Rahman MS: Ovarian tumors in children and adolescents—a clinical study of 52 patients in a university hospital. J Pediatr Adolesc Gynecol. 2011, 24: 25-28. 10.1016/j.jpag.2010.06.005.CrossRefPubMed
12.
go back to reference Deligeoroglou E, Eleftheriades M, Shiadoes V, Botsis D, Hasiakos D, Kontoravdis A, Creatsas G: Ovarian masses during adolescence: clinical, ultrasonographic and pathologic findings, serum tumor markers and endocrinological profile. Gynecol Endocrinol. 2004, 19: 1-8. 10.1080/09513590410001712895.CrossRefPubMed Deligeoroglou E, Eleftheriades M, Shiadoes V, Botsis D, Hasiakos D, Kontoravdis A, Creatsas G: Ovarian masses during adolescence: clinical, ultrasonographic and pathologic findings, serum tumor markers and endocrinological profile. Gynecol Endocrinol. 2004, 19: 1-8. 10.1080/09513590410001712895.CrossRefPubMed
13.
go back to reference Emin U, Tayfun G, Cantekin I, Ozlem UB, Umit B, Leyla M: Tumor markers in mature cystic teratomas of the ovary. Arch Gynecol Obstet. 2009, 279: 145-147. 10.1007/s00404-008-0688-2.CrossRefPubMed Emin U, Tayfun G, Cantekin I, Ozlem UB, Umit B, Leyla M: Tumor markers in mature cystic teratomas of the ovary. Arch Gynecol Obstet. 2009, 279: 145-147. 10.1007/s00404-008-0688-2.CrossRefPubMed
14.
go back to reference Bast RC, Badgwell D, Lu Z, Marquez R, Rosen D, Liu J, Baggerly KA, Atkinson EN, Skates S, Zhang Z, Lokshin A, Menon U, Jacobs I, Lu K, Bast RC, Badgwell D, Lu Z, Marquez R, Rosen D, Liu J, Baggerly KA, Atkinson EN, Skates S, Zhang Z, Lokshin A, Menon U, Jacobs I, Lu K: New tumor markers: CA125 and beyond. Int J Gynecol Cancer. 2005, 15: 274-281. 10.1111/j.1525-1438.2005.00441.x.CrossRefPubMed Bast RC, Badgwell D, Lu Z, Marquez R, Rosen D, Liu J, Baggerly KA, Atkinson EN, Skates S, Zhang Z, Lokshin A, Menon U, Jacobs I, Lu K, Bast RC, Badgwell D, Lu Z, Marquez R, Rosen D, Liu J, Baggerly KA, Atkinson EN, Skates S, Zhang Z, Lokshin A, Menon U, Jacobs I, Lu K: New tumor markers: CA125 and beyond. Int J Gynecol Cancer. 2005, 15: 274-281. 10.1111/j.1525-1438.2005.00441.x.CrossRefPubMed
15.
go back to reference Laberge PY, Levesque S: Short-term morbidity and long-term recurrence rate of ovarian dermoid cysts treated by laparoscopy versus laparotomy. J Obstet Gynaecol Can. 2006, 28: 789-793.CrossRefPubMed Laberge PY, Levesque S: Short-term morbidity and long-term recurrence rate of ovarian dermoid cysts treated by laparoscopy versus laparotomy. J Obstet Gynaecol Can. 2006, 28: 789-793.CrossRefPubMed
16.
go back to reference Seracchioli R, Venturoli S, Colombo FM, Govoni F, Missiroli S, Bagnoli A: Fertility and tumor recurrence rate after conservative laparoscopic management of young women with early-stage borderline ovarian tumors. Fertil Steril. 2001, 76: 999-1004. 10.1016/S0015-0282(01)02842-4.CrossRefPubMed Seracchioli R, Venturoli S, Colombo FM, Govoni F, Missiroli S, Bagnoli A: Fertility and tumor recurrence rate after conservative laparoscopic management of young women with early-stage borderline ovarian tumors. Fertil Steril. 2001, 76: 999-1004. 10.1016/S0015-0282(01)02842-4.CrossRefPubMed
17.
go back to reference Doss N, Forney JP, Vellios F, Nalick RH: Covert bilaterality of mature ovarian teratomas. Obstet Gynecol. 1977, 50: 651-653.PubMed Doss N, Forney JP, Vellios F, Nalick RH: Covert bilaterality of mature ovarian teratomas. Obstet Gynecol. 1977, 50: 651-653.PubMed
18.
go back to reference Harada M, Osuga Y, Fujimoto A, Fujii T, Yano T, Kozuma S: Predictive factors for recurrence of ovarian mature cystic teratomas after surgical excision. Eur J Obstet Gynecol Reprod Biol. 2013, 171: 325-328. 10.1016/j.ejogrb.2013.09.004.CrossRefPubMed Harada M, Osuga Y, Fujimoto A, Fujii T, Yano T, Kozuma S: Predictive factors for recurrence of ovarian mature cystic teratomas after surgical excision. Eur J Obstet Gynecol Reprod Biol. 2013, 171: 325-328. 10.1016/j.ejogrb.2013.09.004.CrossRefPubMed
Metadata
Title
A case of recurrent, bilateral ovarian mature teratoma in a young woman
Authors
Che-Fu Chang
Chen-Kuo Lin
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2014
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/1472-6874-14-57

Other articles of this Issue 1/2014

BMC Women's Health 1/2014 Go to the issue