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BMC Oral Health

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Open Access 01-12-2009 | Research article

Periodontal conditions, oral Candida albicans and salivary proteins in type 2 diabetic subjects with emphasis on gender

Authors: Fawad Javed, Lena Klingspor, Ulf Sundin, Mohammad Altamash, Björn Klinge, Per-Erik Engström

Published in: BMC Oral Health | Issue 1/2009

Abstract

Background

The association between periodontal conditions, oral yeast colonisation and salivary proteins in subjects with type 2 diabetes (T2D) is not yet documented. The present study aimed to assess the relationship between these variables in type 2 diabetic subjects with reference to gender.

Methods

Fifty-eight type 2 diabetic subjects (23 males and 35 females) with random blood glucose level ≥ 11.1 mmol/L were investigated. Periodontal conditions (plaque index [PI], bleeding on probing [BOP], probing pocket depth [PD] (4 to 6 mm and ≥ 6 mm), oral yeasts, salivary immunoglobulin (Ig) A, IgG and total protein concentrations, and number of present teeth were determined.

Results

Periodontal conditions (PI [p < 0.00001], BOP [p < 0.01] and PD of 4 to 6 mm [p < 0.001], salivary IgG (μg)/mg protein (p < 0.001) and salivary total protein concentrations (p < 0.05) were higher in type 2 diabetic females with Candida albicans (C. albicans) colonisation compared to males in the same group. Type 2 diabetic females with C. albicans colonisation had more teeth compared to males in the same group (p < 0.0001).

Conclusion

Clinical and salivary parameters of periodontal inflammation (BOP and IgG (μg)/mg protein) were higher in type 2 diabetic females with oral C. albicans colonisation compared to males in the same group. Further studies are warranted to evaluate the association of gender with these variables in subjects with T2D.

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1472-6831/9/12/prepub

Title: Periodontal conditions, oral Candida albicans and salivary proteins in type 2 diabetic subjects with emphasis on gender
Authors: Fawad Javed
Lena Klingspor
Ulf Sundin
Mohammad Altamash
Björn Klinge
Per-Erik Engström
Publication date: 01-12-2009
Publisher: BioMed Central
Published in: BMC Oral Health / Issue 1/2009
Electronic ISSN: 1472-6831
DOI: https://doi.org/10.1186/1472-6831-9-12

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Periodontal conditions, oral Candida albicans and salivary proteins in type 2 diabetic subjects with emphasis on gender

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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