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BMC Surgery
Published in: BMC Surgery 1/2002

Open Access 01-12-2002 | Research article

Is endosonography an effective method for detection and local staging of the ampullary carcinoma? A prospective study

Authors: Panagiotis Skordilis, Ioannis A Mouzas, Philippos D Dimoulios, Georgios Alexandrakis, Joanna Moschandrea, Elias Kouroumalis

Published in: BMC Surgery | Issue 1/2002

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Abstract

Background

The relatively rare carcinoma of the ampulla of Vater is a neoplasia with a good prognosis compared to pancreatic cancer. Preoperative staging is important in planning the most suitable surgical intervention.

Aim

To prospectively evaluate the diagnostic accuracy of Endoscopic Ultrasonography (EUS) in comparison with conventional US and CT scan, in staging of patients with ampullary carcinoma.

Patients and Methods

20 patients (7 women and 13 men) with histologically proven carcinoma of the ampulla of Vater were assessed by EUS, CT scan and US. Results were compared to surgical findings.

Results

Endoscopic biopsies were diagnostic in 76% of the patients. Detection of ampullary cancer with US and CT scan was 15% and 20% respectively. Only indirect signs of the disease were identified in the majority of cases using these methods. Overall accuracy of EUS in detection of ampullary tumours was 100%. The EUS was significantly (p < 0.001) superior than US and CT scan in ampullary carcinoma detection. Tumour size, tumour extension and the existence of metastatic lymph nodes were also identified and EUS proved to be very useful for the preoperative classification both for the T and the N components of the TNM staging of this neoplasia. The diagnostic accuracy for tumour extension (T) was 82% and for detection of metastatic lymph nodes (N) was 71%.

Conclusion

EUS is more accurate in detecting ampullary cancer than US and CT scan. Tumor extension and locally metastatic lymph nodes are more accurately assessed by means of EUS than with other imaging methods.
Appendix
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Metadata
Title
Is endosonography an effective method for detection and local staging of the ampullary carcinoma? A prospective study
Authors
Panagiotis Skordilis
Ioannis A Mouzas
Philippos D Dimoulios
Georgios Alexandrakis
Joanna Moschandrea
Elias Kouroumalis
Publication date
01-12-2002
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2002
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/1471-2482-2-1

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