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Published in: BMC Surgery 2/2013

Open Access 01-10-2013 | Research article

Mediterranean diet and cancer: epidemiological evidence and mechanism of selected aspects

Authors: Giuseppe Grosso, Silvio Buscemi, Fabio Galvano, Antonio Mistretta, Stefano Marventano, Vanessa La Vela, Filippo Drago, Santi Gangi, Francesco Basile, Antonio Biondi

Published in: BMC Surgery | Special Issue 2/2013

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Abstract

Background

Populations living in the area of the Mediterranean Sea suffered by decreased incidence of cancer compared with those living in the regions of northern Europe and US countries, attributed to healthier dietary habits. Nowadays, we are assisting to a moving away from the traditional Mediterranean dietary pattern, but whether this changing is influencing risk of cancers is still unclear. The aim of the study was to review recent evidence on potential relationship between the adherence to the Mediterranean diet and cancer.

Discussion

The most recent pooled analyses of epidemiological studies supported strongly the hypothesis that the Mediterranean diet may play a role in preventing several types of cancers, especially those of digestive tract, whereas contrasting results were reported for hormone-dependent cancers. Specific aspects of the Mediterranean diet such as high fruit and vegetables and low red processed meat intake may explain such protective effects. Moreover, evidence regarding olive oil and whole grains increase the beneficial effects of such dietary pattern against cancer.

Conclusions

Literature evidence actually demonstrates that the increased adherence to the Mediterranean dietary pattern is beneficial to health across populations and may translate a protective effect with certain cancers.
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Metadata
Title
Mediterranean diet and cancer: epidemiological evidence and mechanism of selected aspects
Authors
Giuseppe Grosso
Silvio Buscemi
Fabio Galvano
Antonio Mistretta
Stefano Marventano
Vanessa La Vela
Filippo Drago
Santi Gangi
Francesco Basile
Antonio Biondi
Publication date
01-10-2013
Publisher
BioMed Central
Published in
BMC Surgery / Issue Special Issue 2/2013
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/1471-2482-13-S2-S14

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