Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2014

Open Access 01-12-2014 | Research article

Comparison of two-stage open versus percutaneous pedicle screw fixation in treating pyogenic spondylodiscitis

Authors: Tung-Yi Lin, Tsung-Ting Tsai, Meng-Ling Lu, Chi-Chien Niu, Ming-Kai Hsieh, Tsai-Sheng Fu, Po-Liang Lai, Lih-Huei Chen, Wen-Jer Chen

Published in: BMC Musculoskeletal Disorders | Issue 1/2014

Login to get access

Abstract

Background

Percutaneous pedicle screw instrumentation is a minimally invasive surgical technique; however, the effects of using percutaneous pedicle screw fixation in treating patients with spinal infections have not yet been well demonstrated. The aim of this study, therefore, was to determine whether percutaneous posterior pedicle screw instrumentation is superior to the traditional open approach in treating pyogenic spondylodiscitis.

Methods

We retrospectively reviewed data for 45 patients treated for pyogenic spondylodiscitis with anterior debridement and interbody fusion followed by a second-stage procedure involving either traditional open posterior pedicle screw fixation or percutaneous posterior pedicle screw fixation. Twenty patients underwent percutaneous fixation and 25 patients underwent open fixation. Demographic, operative, and perioperative data were collected and analyzed.

Results

The average operative time for the percutaneous procedure was 102.5 minutes, while the average time for the open procedure was 129 minutes. The average blood loss for the percutaneous patients was 89 ml versus a 344.8 ml average for the patients in the open group. Patients who underwent the minimally invasive surgery had lower visual analogue scale scores and required significantly less analgesia afterwards. After two years of follow-up, neither recurrent infection nor intraoperative complications, such as wound infection or screw loosening, were found in the percutaneous group. Moreover, there was no significant difference in outcome between the two groups in terms of Oswestry Disability Index scores.

Conclusions

Anterior debridement and interbody fusion with bone grafting followed by minimally invasive percutaneous posterior instrumentation is an alternative treatment for pyogenic spondylodiscitis which can result in less intraoperative blood loss, shorter operative time, and reduced postoperative pain with no adverse effect on infection control.
Appendix
Available only for authorised users
Literature
1.
go back to reference Carragee EJ: Pyogenic vertebral osteomyelitis. J Bone Joint Surg Am. 1997, 79 (6): 874-880.PubMed Carragee EJ: Pyogenic vertebral osteomyelitis. J Bone Joint Surg Am. 1997, 79 (6): 874-880.PubMed
2.
go back to reference Pintado-Garcia V: Infectious spondylitis. Enferm Infecc Microbiol Clin. 2008, 26 (8): 510-517. 10.1016/S0213-005X(08)72781-2.CrossRefPubMed Pintado-Garcia V: Infectious spondylitis. Enferm Infecc Microbiol Clin. 2008, 26 (8): 510-517. 10.1016/S0213-005X(08)72781-2.CrossRefPubMed
3.
go back to reference Martinez Hernandez PL, Amer Lopez M, Zamora Vargas F, Garcia de Paso P, Navarro San Francisco C, Perez Fernandez E, Montoya Lozano F, Vazquez Munoz E: Spontaneous infectious spondylodiscitis in an internal medicine department: epidemiological and clinical study in 41 cases. Rev Clin Esp. 2008, 208 (7): 347-352. 10.1157/13124314.CrossRefPubMed Martinez Hernandez PL, Amer Lopez M, Zamora Vargas F, Garcia de Paso P, Navarro San Francisco C, Perez Fernandez E, Montoya Lozano F, Vazquez Munoz E: Spontaneous infectious spondylodiscitis in an internal medicine department: epidemiological and clinical study in 41 cases. Rev Clin Esp. 2008, 208 (7): 347-352. 10.1157/13124314.CrossRefPubMed
4.
go back to reference Hodgson AR, Stock FE, Fang HS, Ong GB: Anterior spinal fusion. The operative approach and pathological findings in 412 patients with Pott’s disease of the spine. Br J Surg. 1960, 48: 172-178. 10.1002/bjs.18004820819.CrossRefPubMed Hodgson AR, Stock FE, Fang HS, Ong GB: Anterior spinal fusion. The operative approach and pathological findings in 412 patients with Pott’s disease of the spine. Br J Surg. 1960, 48: 172-178. 10.1002/bjs.18004820819.CrossRefPubMed
5.
go back to reference Emery SE, Chan DP, Woodward HR: Treatment of hematogenous pyogenic vertebral osteomyelitis with anterior debridement and primary bone grafting. Spine (Phila Pa 1976). 1989, 14 (3): 284-291. Emery SE, Chan DP, Woodward HR: Treatment of hematogenous pyogenic vertebral osteomyelitis with anterior debridement and primary bone grafting. Spine (Phila Pa 1976). 1989, 14 (3): 284-291.
6.
go back to reference Dimar JR, Carreon LY, Glassman SD, Campbell MJ, Hartman MJ, Johnson JR: Treatment of pyogenic vertebral osteomyelitis with anterior debridement and fusion followed by delayed posterior spinal fusion. Spine (Phila Pa 1976). 2004, 29 (3): 326-332. 10.1097/01.BRS.0000109410.46538.74. discussion 332CrossRef Dimar JR, Carreon LY, Glassman SD, Campbell MJ, Hartman MJ, Johnson JR: Treatment of pyogenic vertebral osteomyelitis with anterior debridement and fusion followed by delayed posterior spinal fusion. Spine (Phila Pa 1976). 2004, 29 (3): 326-332. 10.1097/01.BRS.0000109410.46538.74. discussion 332CrossRef
7.
go back to reference Foley KT, Gupta SK: Percutaneous pedicle screw fixation of the lumbar spine: preliminary clinical results. J Neurosurg. 2002, 97 (1 Suppl): 7-12.PubMed Foley KT, Gupta SK: Percutaneous pedicle screw fixation of the lumbar spine: preliminary clinical results. J Neurosurg. 2002, 97 (1 Suppl): 7-12.PubMed
8.
go back to reference Nasto LA, Colangelo D, Mazzotta V, Di Meco E, Neri V, Nasto RA, Fantoni M, Pola E: Is posterior percutaneous screw-rod instrumentation a safe and effective alternative approach to TLSO rigid bracing for single-level pyogenic spondylodiscitis? Results of a retrospective cohort analysis. Spine J. 2014, 14 (7): 1139-1146. 10.1016/j.spinee.2013.07.479.CrossRefPubMed Nasto LA, Colangelo D, Mazzotta V, Di Meco E, Neri V, Nasto RA, Fantoni M, Pola E: Is posterior percutaneous screw-rod instrumentation a safe and effective alternative approach to TLSO rigid bracing for single-level pyogenic spondylodiscitis? Results of a retrospective cohort analysis. Spine J. 2014, 14 (7): 1139-1146. 10.1016/j.spinee.2013.07.479.CrossRefPubMed
9.
go back to reference Deininger MH, Unfried MI, Vougioukas VI, Hubbe U: Minimally invasive dorsal percutaneous spondylodesis for the treatment of adult pyogenic spondylodiscitis. Acta Neurochir (Wien). 2009, 151 (11): 1451-1457. 10.1007/s00701-009-0377-3.CrossRef Deininger MH, Unfried MI, Vougioukas VI, Hubbe U: Minimally invasive dorsal percutaneous spondylodesis for the treatment of adult pyogenic spondylodiscitis. Acta Neurochir (Wien). 2009, 151 (11): 1451-1457. 10.1007/s00701-009-0377-3.CrossRef
10.
go back to reference Sahoo PK: Percutaneous pedicle screw and rod insertion for fracture of the lumbar spine. Indian J Neurotrauma. 2005, 2 (2): 143-148. 10.1016/S0973-0508(05)80032-2.CrossRef Sahoo PK: Percutaneous pedicle screw and rod insertion for fracture of the lumbar spine. Indian J Neurotrauma. 2005, 2 (2): 143-148. 10.1016/S0973-0508(05)80032-2.CrossRef
11.
go back to reference Mobbs RJ, Sivabalan P, Li JE: Technique, challenges and indications for percutaneous pedicle screw fixation. J Clin Neurosci. 2011, 18 (6): 741-749. 10.1016/j.jocn.2010.09.019.CrossRefPubMed Mobbs RJ, Sivabalan P, Li JE: Technique, challenges and indications for percutaneous pedicle screw fixation. J Clin Neurosci. 2011, 18 (6): 741-749. 10.1016/j.jocn.2010.09.019.CrossRefPubMed
12.
go back to reference McGuire RA, Eismont FJ: The fate of autogenous bone graft in surgically treated pyogenic vertebral osteomyelitis. J Spinal Disord. 1994, 7 (3): 206-215. 10.1097/00002517-199407030-00002.CrossRefPubMed McGuire RA, Eismont FJ: The fate of autogenous bone graft in surgically treated pyogenic vertebral osteomyelitis. J Spinal Disord. 1994, 7 (3): 206-215. 10.1097/00002517-199407030-00002.CrossRefPubMed
13.
go back to reference Pee YH, Park JD, Choi YG, Lee SH: Anterior debridement and fusion followed by posterior pedicle screw fixation in pyogenic spondylodiscitis: autologous iliac bone strut versus cage. J Neurosurg Spine. 2008, 8 (5): 405-412. 10.3171/SPI/2008/8/5/405.CrossRefPubMed Pee YH, Park JD, Choi YG, Lee SH: Anterior debridement and fusion followed by posterior pedicle screw fixation in pyogenic spondylodiscitis: autologous iliac bone strut versus cage. J Neurosurg Spine. 2008, 8 (5): 405-412. 10.3171/SPI/2008/8/5/405.CrossRefPubMed
14.
go back to reference Fang D, Cheung KM, Dos Remedios ID, Lee YK, Leong JC: Pyogenic vertebral osteomyelitis: treatment by anterior spinal debridement and fusion. J Spinal Disord. 1994, 7 (2): 173-180. 10.1097/00002517-199407020-00012.CrossRefPubMed Fang D, Cheung KM, Dos Remedios ID, Lee YK, Leong JC: Pyogenic vertebral osteomyelitis: treatment by anterior spinal debridement and fusion. J Spinal Disord. 1994, 7 (2): 173-180. 10.1097/00002517-199407020-00012.CrossRefPubMed
15.
go back to reference Sundararaj GD, Babu N, Amritanand R, Venkatesh K, Nithyananth M, Cherian VM, Lee VN: Treatment of haematogenous pyogenic vertebral osteomyelitis by single-stage anterior debridement, grafting of the defect and posterior instrumentation. J Bone Joint Surg (Br). 2007, 89 (9): 1201-1205.CrossRef Sundararaj GD, Babu N, Amritanand R, Venkatesh K, Nithyananth M, Cherian VM, Lee VN: Treatment of haematogenous pyogenic vertebral osteomyelitis by single-stage anterior debridement, grafting of the defect and posterior instrumentation. J Bone Joint Surg (Br). 2007, 89 (9): 1201-1205.CrossRef
16.
go back to reference Korovessis P, Baikousis A, Zacharatos S, Petsinis G, Koureas G, Iliopoulos P: Combined anterior plus posterior stabilization versus posterior short-segment instrumentation and fusion for mid-lumbar (L2-L4) burst fractures. Spine (Phila Pa 1976). 2006, 31 (8): 859-868. 10.1097/01.brs.0000209251.65417.16.CrossRef Korovessis P, Baikousis A, Zacharatos S, Petsinis G, Koureas G, Iliopoulos P: Combined anterior plus posterior stabilization versus posterior short-segment instrumentation and fusion for mid-lumbar (L2-L4) burst fractures. Spine (Phila Pa 1976). 2006, 31 (8): 859-868. 10.1097/01.brs.0000209251.65417.16.CrossRef
17.
go back to reference Korovessis P, Hadjipavlou A, Repantis T: Minimal invasive short posterior instrumentation plus balloon kyphoplasty with calcium phosphate for burst and severe compression lumbar fractures. Spine (Phila Pa 1976). 2008, 33 (6): 658-667. 10.1097/BRS.0b013e318166e0bb.CrossRef Korovessis P, Hadjipavlou A, Repantis T: Minimal invasive short posterior instrumentation plus balloon kyphoplasty with calcium phosphate for burst and severe compression lumbar fractures. Spine (Phila Pa 1976). 2008, 33 (6): 658-667. 10.1097/BRS.0b013e318166e0bb.CrossRef
18.
go back to reference Dickerman RD, East JW, Winters K, Tackett J, Hajovsky-Pietla A: Anterior and posterior lumbar interbody fusion with percutaneous pedicle screws: comparison to muscle damage and minimally invasive techniques. Spine (Phila Pa 1976). 2009, 34 (25): E923-E925. 10.1097/BRS.0b013e3181af0523.CrossRef Dickerman RD, East JW, Winters K, Tackett J, Hajovsky-Pietla A: Anterior and posterior lumbar interbody fusion with percutaneous pedicle screws: comparison to muscle damage and minimally invasive techniques. Spine (Phila Pa 1976). 2009, 34 (25): E923-E925. 10.1097/BRS.0b013e3181af0523.CrossRef
19.
go back to reference Gejo R, Matsui H, Kawaguchi Y, Ishihara H, Tsuji H: Serial changes in trunk muscle performance after posterior lumbar surgery. Spine (Phila Pa 1976). 1999, 24 (10): 1023-1028. 10.1097/00007632-199905150-00017.CrossRef Gejo R, Matsui H, Kawaguchi Y, Ishihara H, Tsuji H: Serial changes in trunk muscle performance after posterior lumbar surgery. Spine (Phila Pa 1976). 1999, 24 (10): 1023-1028. 10.1097/00007632-199905150-00017.CrossRef
20.
go back to reference Safran O, Rand N, Kaplan L, Sagiv S, Floman Y: Sequential or simultaneous, same-day anterior decompression and posterior stabilization in the management of vertebral osteomyelitis of the lumbar spine. Spine (Phila Pa 1976). 1998, 23 (17): 1885-1890. 10.1097/00007632-199809010-00018.CrossRef Safran O, Rand N, Kaplan L, Sagiv S, Floman Y: Sequential or simultaneous, same-day anterior decompression and posterior stabilization in the management of vertebral osteomyelitis of the lumbar spine. Spine (Phila Pa 1976). 1998, 23 (17): 1885-1890. 10.1097/00007632-199809010-00018.CrossRef
21.
go back to reference Korovessis P, Petsinis G, Koureas G, Iliopoulos P, Zacharatos S: One-stage combined surgery with mesh cages for treatment of septic spondylitis. Clin Orthop Relat Res. 2006, 444: 51-59.CrossRefPubMed Korovessis P, Petsinis G, Koureas G, Iliopoulos P, Zacharatos S: One-stage combined surgery with mesh cages for treatment of septic spondylitis. Clin Orthop Relat Res. 2006, 444: 51-59.CrossRefPubMed
22.
go back to reference Kim JS, Choi WG, Lee SH: Minimally invasive anterior lumbar interbody fusion followed by percutaneous pedicle screw fixation for isthmic spondylolisthesis: minimum 5-year follow-up. Spine J. 2010, 10 (5): 404-409. 10.1016/j.spinee.2010.02.022.CrossRefPubMed Kim JS, Choi WG, Lee SH: Minimally invasive anterior lumbar interbody fusion followed by percutaneous pedicle screw fixation for isthmic spondylolisthesis: minimum 5-year follow-up. Spine J. 2010, 10 (5): 404-409. 10.1016/j.spinee.2010.02.022.CrossRefPubMed
23.
go back to reference Maciejczak A, Barnas P, Dudziak P, Jagiello-Bajer B, Litwora B, Sumara M: Posterior keyhole corpectomy with percutaneous pedicle screw stabilization in the surgical management of lumbar burst fractures. Neurosurgery. 2007, 60 (4 Suppl 2): 232-241. discussion 241–232PubMed Maciejczak A, Barnas P, Dudziak P, Jagiello-Bajer B, Litwora B, Sumara M: Posterior keyhole corpectomy with percutaneous pedicle screw stabilization in the surgical management of lumbar burst fractures. Neurosurgery. 2007, 60 (4 Suppl 2): 232-241. discussion 241–232PubMed
24.
go back to reference Yang SC, Fu TS, Chen LH, Chen WJ, Tu YK: Identifying pathogens of spondylodiscitis: percutaneous endoscopy or CT-guided biopsy. Clin Orthop Relat Res. 2008, 466 (12): 3086-3092. 10.1007/s11999-008-0441-y.CrossRefPubMedPubMedCentral Yang SC, Fu TS, Chen LH, Chen WJ, Tu YK: Identifying pathogens of spondylodiscitis: percutaneous endoscopy or CT-guided biopsy. Clin Orthop Relat Res. 2008, 466 (12): 3086-3092. 10.1007/s11999-008-0441-y.CrossRefPubMedPubMedCentral
25.
go back to reference Hadjipavlou AG, Katonis PK, Gaitanis IN, Muffoletto AJ, Tzermiadianos MN, Crow W: Percutaneous transpedicular discectomy and drainage in pyogenic spondylodiscitis. Eur Spine J. 2004, 13 (8): 707-713. 10.1007/s00586-004-0699-z.CrossRefPubMedPubMedCentral Hadjipavlou AG, Katonis PK, Gaitanis IN, Muffoletto AJ, Tzermiadianos MN, Crow W: Percutaneous transpedicular discectomy and drainage in pyogenic spondylodiscitis. Eur Spine J. 2004, 13 (8): 707-713. 10.1007/s00586-004-0699-z.CrossRefPubMedPubMedCentral
26.
go back to reference Kandwal P, Garg B, Upendra B, Chowdhury B, Jayaswal A: Outcome of minimally invasive surgery in the management of tuberculous spondylitis. Indian J Orthop. 2012, 46 (2): 159-164. 10.4103/0019-5413.93680.CrossRefPubMedPubMedCentral Kandwal P, Garg B, Upendra B, Chowdhury B, Jayaswal A: Outcome of minimally invasive surgery in the management of tuberculous spondylitis. Indian J Orthop. 2012, 46 (2): 159-164. 10.4103/0019-5413.93680.CrossRefPubMedPubMedCentral
27.
go back to reference Faciszewski T, Winter RB, Lonstein JE, Denis F, Johnson L: The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine (Phila Pa 1976). 1995, 20 (14): 1592-1599. 10.1097/00007632-199507150-00007.CrossRef Faciszewski T, Winter RB, Lonstein JE, Denis F, Johnson L: The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine (Phila Pa 1976). 1995, 20 (14): 1592-1599. 10.1097/00007632-199507150-00007.CrossRef
28.
go back to reference Kaneda K, Taneichi H, Abumi K, Hashimoto T, Satoh S, Fujiya M: Anterior decompression and stabilization with the Kaneda device for thoracolumbar burst fractures associated with neurological deficits. J Bone Joint Surg Am. 1997, 79 (1): 69-83.PubMed Kaneda K, Taneichi H, Abumi K, Hashimoto T, Satoh S, Fujiya M: Anterior decompression and stabilization with the Kaneda device for thoracolumbar burst fractures associated with neurological deficits. J Bone Joint Surg Am. 1997, 79 (1): 69-83.PubMed
Metadata
Title
Comparison of two-stage open versus percutaneous pedicle screw fixation in treating pyogenic spondylodiscitis
Authors
Tung-Yi Lin
Tsung-Ting Tsai
Meng-Ling Lu
Chi-Chien Niu
Ming-Kai Hsieh
Tsai-Sheng Fu
Po-Liang Lai
Lih-Huei Chen
Wen-Jer Chen
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2014
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-15-443

Other articles of this Issue 1/2014

BMC Musculoskeletal Disorders 1/2014 Go to the issue