Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2010

Open Access 01-12-2010 | Research article

Clinical and radiographic outcomes of the treatment of adolescent idiopathic scoliosis with segmental pedicle screws and combined local autograft and allograft bone for spinal fusion: a retrospective case series

Authors: Xiaoming Yang, Hongguang Xu, Ming Li, Suxi Gu, Xiutong Fang, Jingjie Wang, Jianqiang Ni, Dajiang Wu

Published in: BMC Musculoskeletal Disorders | Issue 1/2010

Login to get access

Abstract

Background

High morbidity has been reported with iliac crest bone graft harvesting; however, donor bone is typically necessary for posterior spinal fusion. Autograft bone combined with allograft may reduce the morbidity associated with iliac crest bone harvesting and improve the fusion rate. Our aim in this study was to determine the presence of complications, pseudarthrosis, non-union, and infection using combined in situ local autograft bone and freeze-dried cancellous allograft bone in patients undergoing posterior spinal fusion for the treatment of adolescent idiopathic scoliosis.

Methods

A combination of in situ local autograft bone and freeze-dried cancellous allograft blocks were used in 50 consecutive patients with adolescent idiopathic scoliosis treated by posterior fusion and Moss Miami pedicle screw instrumentation. Results were assessed clinically and radiographically and quality of life and functional outcome was evaluated by administration of a Chinese version of the SRS-22 survey.

Results

There were 41 female and 9 male patients included for analysis with an average age of 14.7 years (range, 12-17). All patients had a minimum follow-up of 18 months (range, 18 to 40 months). The average preoperative Cobb angle was 49.8° (range, 40° to 86°). The average number of levels fused was 9.8 (range, 6-15). Patients had a minimum postoperative follow-up of 18 months. At final follow-up, the average Cobb angle correction was 77.8% (range, 43.4 to 92.5%). There was no obvious loss in the correction, and the average loss of correction was 1.1° (range, 0° to 4°). There was no pseudarthrosis and no major complications.

Conclusions

In situ autograft bone combined with allograft bone may be a promising method enhances spinal fusion in AIS treated with pedicle screw placement. By eliminating the need for iliac crest bone harvesting, significant morbidity may be avoided.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kager AN, Marks M, Bastrom T, Newton PO: Morbidity of iliac crest bone graft harvesting in adolescent deformity surgery. J Pediatr Orthop. 2006, 26: 132-134. 10.1097/01.bpo.0000188996.36674.56.CrossRefPubMed Kager AN, Marks M, Bastrom T, Newton PO: Morbidity of iliac crest bone graft harvesting in adolescent deformity surgery. J Pediatr Orthop. 2006, 26: 132-134. 10.1097/01.bpo.0000188996.36674.56.CrossRefPubMed
2.
go back to reference Skaggs DL, Samuelson MA, Hale JM, Kay RM, Tolo VT: Complications of posterior iliac crest bone grafting in spine surgery in children. Spine. 2000, 25: 2400-2402. 10.1097/00007632-200009150-00021.CrossRefPubMed Skaggs DL, Samuelson MA, Hale JM, Kay RM, Tolo VT: Complications of posterior iliac crest bone grafting in spine surgery in children. Spine. 2000, 25: 2400-2402. 10.1097/00007632-200009150-00021.CrossRefPubMed
3.
go back to reference Silber JS, Anderson DG, Daffner SD, Brislin BT, Leland JM, Hilibrand AS, Vaccaro AR, Albert TJ: Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion. Spine. 2003, 28: 134-139. 10.1097/00007632-200301150-00008.CrossRefPubMed Silber JS, Anderson DG, Daffner SD, Brislin BT, Leland JM, Hilibrand AS, Vaccaro AR, Albert TJ: Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion. Spine. 2003, 28: 134-139. 10.1097/00007632-200301150-00008.CrossRefPubMed
4.
go back to reference Blanco JS, Sears CJ: Allograft bone use during instrumentation and fusion in the treatment of adolescent idiopathic scoliosis. Spine. 1997, 22: 1338-1342. 10.1097/00007632-199706150-00011.CrossRefPubMed Blanco JS, Sears CJ: Allograft bone use during instrumentation and fusion in the treatment of adolescent idiopathic scoliosis. Spine. 1997, 22: 1338-1342. 10.1097/00007632-199706150-00011.CrossRefPubMed
5.
go back to reference Knapp DR, Jones ET, Blanco JS, Flynn JC, Price CT: Allograft bone in spinal fusion for adolescent idiopathic scoliosis. J Spinal Disord Tech. 2005, 18: S73-S76. 10.1097/01.bsd.0000128694.21405.80.CrossRefPubMed Knapp DR, Jones ET, Blanco JS, Flynn JC, Price CT: Allograft bone in spinal fusion for adolescent idiopathic scoliosis. J Spinal Disord Tech. 2005, 18: S73-S76. 10.1097/01.bsd.0000128694.21405.80.CrossRefPubMed
6.
go back to reference Kim YJ, Lenke LG, Cho SK, Bridwell KH, Sides B, Blanke K: Free hand pedicle screw placement in the thoracic spine: Is it safe?. Spine. 2004, 29: 333-342. 10.1097/01.BRS.0000109983.12113.9B.CrossRefPubMed Kim YJ, Lenke LG, Cho SK, Bridwell KH, Sides B, Blanke K: Free hand pedicle screw placement in the thoracic spine: Is it safe?. Spine. 2004, 29: 333-342. 10.1097/01.BRS.0000109983.12113.9B.CrossRefPubMed
7.
go back to reference Betz RR, Petrizzo AM, Kerner PJ, Falatyn SP, Clements DH, Huss GK: Allograft versus no graft with a posterior multisegmented hook system for the treatment of idiopathic scoliosis. Spine. 2006, 3: 121-127. 10.1097/01.brs.0000194771.49774.77.CrossRef Betz RR, Petrizzo AM, Kerner PJ, Falatyn SP, Clements DH, Huss GK: Allograft versus no graft with a posterior multisegmented hook system for the treatment of idiopathic scoliosis. Spine. 2006, 3: 121-127. 10.1097/01.brs.0000194771.49774.77.CrossRef
8.
go back to reference Cheung KM, Senkoylu A, Alanay A, Genc Y, Lau S, Luk KD: Reliability and concurrent validity of the adapted Chinese version of Scoliosis Research Society-22 (SRS-22) questionnaire. Spine (Phila Pa 1976). 2007, 32: 1141-1145.CrossRef Cheung KM, Senkoylu A, Alanay A, Genc Y, Lau S, Luk KD: Reliability and concurrent validity of the adapted Chinese version of Scoliosis Research Society-22 (SRS-22) questionnaire. Spine (Phila Pa 1976). 2007, 32: 1141-1145.CrossRef
9.
go back to reference Violas P, Chapuis M, Bracq H: Local autograft bone in the surgical management of adolescent idiopathic scoliosis. Spine. 2004, 29: 189-192. 10.1097/01.BRS.0000105536.65164.B1.CrossRefPubMed Violas P, Chapuis M, Bracq H: Local autograft bone in the surgical management of adolescent idiopathic scoliosis. Spine. 2004, 29: 189-192. 10.1097/01.BRS.0000105536.65164.B1.CrossRefPubMed
10.
go back to reference Grogan DP, Kalen V, Ross TI, Guidera KJ, Pugh LI: Use of allograft bone for posterior spinal fusion in idiopathic scoliosis. Clin Orthop. 1999, 369: 273-278. 10.1097/00003086-199912000-00028.CrossRefPubMed Grogan DP, Kalen V, Ross TI, Guidera KJ, Pugh LI: Use of allograft bone for posterior spinal fusion in idiopathic scoliosis. Clin Orthop. 1999, 369: 273-278. 10.1097/00003086-199912000-00028.CrossRefPubMed
11.
go back to reference Stevenson S: Biology of bone grafts. Orthop Clin North Am. 1999, 30: 543-552. 10.1016/S0030-5898(05)70107-3.CrossRefPubMed Stevenson S: Biology of bone grafts. Orthop Clin North Am. 1999, 30: 543-552. 10.1016/S0030-5898(05)70107-3.CrossRefPubMed
12.
go back to reference Asselmerier MA, Caspari RB, Bottenfield S: A review of allograft processing of the human immuno-deficiency virus. Am J Sports Med. 1993, 21: 170-175. 10.1177/036354659302100202.CrossRef Asselmerier MA, Caspari RB, Bottenfield S: A review of allograft processing of the human immuno-deficiency virus. Am J Sports Med. 1993, 21: 170-175. 10.1177/036354659302100202.CrossRef
13.
go back to reference Boyce T, Edwards J, Scarborough N: Allograft bone: the influence of processing on safety and performance. Ortho Clin North Am. 1999, 30: 571-581. 10.1016/S0030-5898(05)70110-3.CrossRef Boyce T, Edwards J, Scarborough N: Allograft bone: the influence of processing on safety and performance. Ortho Clin North Am. 1999, 30: 571-581. 10.1016/S0030-5898(05)70110-3.CrossRef
14.
go back to reference Suk SI, Lee CK, Kim WJ, Chung YJ, Park YB: Segmental pedicle screw fixation in the treatment of thoracic idiopathic scoliosis. Spine. 1995, 20: 1399-1405.CrossRefPubMed Suk SI, Lee CK, Kim WJ, Chung YJ, Park YB: Segmental pedicle screw fixation in the treatment of thoracic idiopathic scoliosis. Spine. 1995, 20: 1399-1405.CrossRefPubMed
15.
go back to reference Kim YJ, Lenke LG, Cho SK, Bridwell KH, Sides B, Blanke K: Comparative analysis of pedicle screw versus hook instrumentation in posterior spinal fusion of adolescent idiopathic scoliosis. Spine. 2004, 29: 2040-2048. 10.1097/01.brs.0000138268.12324.1a.CrossRefPubMed Kim YJ, Lenke LG, Cho SK, Bridwell KH, Sides B, Blanke K: Comparative analysis of pedicle screw versus hook instrumentation in posterior spinal fusion of adolescent idiopathic scoliosis. Spine. 2004, 29: 2040-2048. 10.1097/01.brs.0000138268.12324.1a.CrossRefPubMed
16.
go back to reference Lowenstein JE, Matsumoto H, Vitale MG, Weidenbaum M, Gomez JA, Lee FY, Hyman JE, Roye DP: Coronal and sagittal plane correction in adolescent idiopathic scoliosis: a comparison between all pedicle screw versus hybrid thoracic hook lumbar screw constructs. Spine. 2007, 32: 448-452. 10.1097/01.brs.0000255030.78293.fd.CrossRefPubMed Lowenstein JE, Matsumoto H, Vitale MG, Weidenbaum M, Gomez JA, Lee FY, Hyman JE, Roye DP: Coronal and sagittal plane correction in adolescent idiopathic scoliosis: a comparison between all pedicle screw versus hybrid thoracic hook lumbar screw constructs. Spine. 2007, 32: 448-452. 10.1097/01.brs.0000255030.78293.fd.CrossRefPubMed
17.
go back to reference Dobbs MB, Lenke LG, Kim YJ, Kamath G, Peelle MW, Bridwell KH: Selective posterior thoracic fusions for adolescent idiopathic scoliosis. Spine. 2006, 31: 2400-2404. 10.1097/01.brs.0000240212.31241.8e.CrossRefPubMed Dobbs MB, Lenke LG, Kim YJ, Kamath G, Peelle MW, Bridwell KH: Selective posterior thoracic fusions for adolescent idiopathic scoliosis. Spine. 2006, 31: 2400-2404. 10.1097/01.brs.0000240212.31241.8e.CrossRefPubMed
18.
go back to reference Betz RR, Petrizzo AM, Kerner PJ, Falatyn SP, Clements DH, Huss GK: Allograft versus no graft with a posterior multisegmented hook system for the treatment of idiopathic scoliosis. Spine (Phila Pa 1976). 2006, 31: 121-127.CrossRef Betz RR, Petrizzo AM, Kerner PJ, Falatyn SP, Clements DH, Huss GK: Allograft versus no graft with a posterior multisegmented hook system for the treatment of idiopathic scoliosis. Spine (Phila Pa 1976). 2006, 31: 121-127.CrossRef
19.
go back to reference Lenke LG, Bridwell KH, Blanke K, Baldus C, Weston J: Radiographic results of arthrodesis with Cotrel-Dubousset instrumentation for the treatment of adolescent idiopathic scoliosis: a five to ten year follow-up study. J Bone Joint Surg Am. 1998, 80: 807-814.PubMed Lenke LG, Bridwell KH, Blanke K, Baldus C, Weston J: Radiographic results of arthrodesis with Cotrel-Dubousset instrumentation for the treatment of adolescent idiopathic scoliosis: a five to ten year follow-up study. J Bone Joint Surg Am. 1998, 80: 807-814.PubMed
Metadata
Title
Clinical and radiographic outcomes of the treatment of adolescent idiopathic scoliosis with segmental pedicle screws and combined local autograft and allograft bone for spinal fusion: a retrospective case series
Authors
Xiaoming Yang
Hongguang Xu
Ming Li
Suxi Gu
Xiutong Fang
Jingjie Wang
Jianqiang Ni
Dajiang Wu
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2010
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-11-159

Other articles of this Issue 1/2010

BMC Musculoskeletal Disorders 1/2010 Go to the issue