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Published in: BMC Public Health 1/2006

Open Access 01-12-2006 | Research article

An investigation of whether factors associated with short-term attrition change or persist over ten years: data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)

Authors: Fiona E Matthews, Mark Chatfield, Carol Brayne, Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)

Published in: BMC Public Health | Issue 1/2006

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Abstract

Background

Factors associated with the loss of participants in long-term longitudinal studies of ageing, due to refusal or moves, have been discussed less than those with short term follow-up.

Methods

In a population-based study of cognition and ageing (the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)), factors associated with dropout due to refusal and moving in the first follow-up period (over two years) are compared with factors associated with dropout over ten years. Participants at 10-year follow-up are compared with their age-standardised baseline contemporaries.

Results

Some consistent trends are found over the longer term. Refusers tended to have poorer cognition, less years of education, not have a family history of dementia and be women. Characteristics of people who moved differed between waves, but the oldest and people in worse health moved more. When surviving and responding individuals at ten years are compared with those of the same age at baseline many differences are found. Individuals of lower social class, education, cognitive ability, in residential care, with sight/hearing problems and poor/fair self-reported health are less likely to be seen after 10 years of follow-up. Individuals report more health problems when they participate in multiple interviews.

Conclusion

The characteristics of refusers in the longer term are similar to those refusing to participate over the shorter term. Long-term follow-up studies will under represent the disadvantaged and disabled but represent full health status of participating individuals better. There are advantages and disadvantages to both short-term and long-term follow-up.
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Literature
1.
go back to reference Chatfield MD, Brayne CE, Matthews FE: A systematic literature review of attrition between waves in longitudinal studies in the elderly shows a consistent pattern of dropout between differing studies. J Clin Epidemiol. 2005, 58: 13-19. 10.1016/j.jclinepi.2004.05.006.CrossRefPubMed Chatfield MD, Brayne CE, Matthews FE: A systematic literature review of attrition between waves in longitudinal studies in the elderly shows a consistent pattern of dropout between differing studies. J Clin Epidemiol. 2005, 58: 13-19. 10.1016/j.jclinepi.2004.05.006.CrossRefPubMed
2.
go back to reference Zunzunegui MV, Beland F, Gutierrez-Cuadra P: Loss to follow-up in a longitudinal study on aging in Spain. J Clin Epidemiol. 2001, 54: 501-510. 10.1016/S0895-4356(00)00325-5.CrossRefPubMed Zunzunegui MV, Beland F, Gutierrez-Cuadra P: Loss to follow-up in a longitudinal study on aging in Spain. J Clin Epidemiol. 2001, 54: 501-510. 10.1016/S0895-4356(00)00325-5.CrossRefPubMed
3.
go back to reference Sugisawa H, Kishino H, Sugihara Y, Shibata H: [Characteristics of dropouts and participants in a twelve-year longitudinal research of Japanese elderly]. Nippon Koshu Eisei Zasshi. 2000, 47: 337-349.PubMed Sugisawa H, Kishino H, Sugihara Y, Shibata H: [Characteristics of dropouts and participants in a twelve-year longitudinal research of Japanese elderly]. Nippon Koshu Eisei Zasshi. 2000, 47: 337-349.PubMed
4.
go back to reference Mihelic AH, Crimmins EM: Loss to follow-up in a sample of Americans 70 years of age and older: The LSOA 1984-1990. J Gerontol B Psychol Sci Soc Sci. 1997, 52: 37-48.CrossRef Mihelic AH, Crimmins EM: Loss to follow-up in a sample of Americans 70 years of age and older: The LSOA 1984-1990. J Gerontol B Psychol Sci Soc Sci. 1997, 52: 37-48.CrossRef
5.
go back to reference Dufouil C, Clayton D, Brayne C, Chi LY, Dening TR, Paykel ES, O'Connor DW, Ahmed A, McGee MA, Huppert FA: Population norms for the MMSE in the very old: estimates based on longitudinal data. Mini-Mental State Examination. Neurology. 2000, 55: 1609-13.CrossRefPubMed Dufouil C, Clayton D, Brayne C, Chi LY, Dening TR, Paykel ES, O'Connor DW, Ahmed A, McGee MA, Huppert FA: Population norms for the MMSE in the very old: estimates based on longitudinal data. Mini-Mental State Examination. Neurology. 2000, 55: 1609-13.CrossRefPubMed
6.
go back to reference Norris FH: Characteristics of older nonrespondents over five waves of a panel study. J Gerontol. 1985, 40: 627-36.CrossRefPubMed Norris FH: Characteristics of older nonrespondents over five waves of a panel study. J Gerontol. 1985, 40: 627-36.CrossRefPubMed
7.
go back to reference Jacomb PA, Jorm AF, Korten AE, Christensen H, Henderson AS: Predictors of refusal to participate: a longitudinal health survey of the elderly in Australia. BMC Public Health. 2002, 2: 4-10.1186/1471-2458-2-4.CrossRefPubMedPubMedCentral Jacomb PA, Jorm AF, Korten AE, Christensen H, Henderson AS: Predictors of refusal to participate: a longitudinal health survey of the elderly in Australia. BMC Public Health. 2002, 2: 4-10.1186/1471-2458-2-4.CrossRefPubMedPubMedCentral
8.
go back to reference MRC CFAS : Cognitive function and dementia in six areas of England and Wales: the distribution of MMSE and prevalence of GMS organicity level in the MRC CFA Study. The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Psychol Med. 1998, 28: 319-335. 10.1017/S0033291797006272.CrossRef MRC CFAS : Cognitive function and dementia in six areas of England and Wales: the distribution of MMSE and prevalence of GMS organicity level in the MRC CFA Study. The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Psychol Med. 1998, 28: 319-335. 10.1017/S0033291797006272.CrossRef
9.
go back to reference Matthews FE, Chatfield M, Freeman C, McCracken C, Brayne C: Attrition and bias in the MRC cognitive function and ageing study: an epidemiological investigation. BMC Public Health. 2004, 4: 12-10.1186/1471-2458-4-12.CrossRefPubMedPubMedCentral Matthews FE, Chatfield M, Freeman C, McCracken C, Brayne C: Attrition and bias in the MRC cognitive function and ageing study: an epidemiological investigation. BMC Public Health. 2004, 4: 12-10.1186/1471-2458-4-12.CrossRefPubMedPubMedCentral
10.
go back to reference Folstein MF, Folstein SE, McHugh PR: "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975, 12: 189-198. 10.1016/0022-3956(75)90026-6.CrossRefPubMed Folstein MF, Folstein SE, McHugh PR: "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975, 12: 189-198. 10.1016/0022-3956(75)90026-6.CrossRefPubMed
11.
go back to reference Neale R, Brayne C, Johnson AL: Cognition and survival: an exploration in a large multicentre study of the population aged 65 years and over. Int J Epidemiol. 2001, 30: 1383-1388. 10.1093/ije/30.6.1383.CrossRefPubMed Neale R, Brayne C, Johnson AL: Cognition and survival: an exploration in a large multicentre study of the population aged 65 years and over. Int J Epidemiol. 2001, 30: 1383-1388. 10.1093/ije/30.6.1383.CrossRefPubMed
12.
go back to reference MRC CFAS : The Medical Research Council Cognitive Function and Ageing Study website [http://www.cfas.ac.uk]. 2006 MRC CFAS : The Medical Research Council Cognitive Function and Ageing Study website [http://​www.​cfas.​ac.​uk]. 2006
13.
go back to reference MRC CFAS , Yip AG, Brayne C, Matthews FE: Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study. Age Ageing. 2006 MRC CFAS , Yip AG, Brayne C, Matthews FE: Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study. Age Ageing. 2006
14.
go back to reference MRC CFAS , Matthews FE, Brayne C: The incidence of dementia in England and Wales: findings from the five identical sites of the MRC CFA Study. PLoS Med. 2005, 2: e193-10.1371/journal.pmed.0020193.CrossRef MRC CFAS , Matthews FE, Brayne C: The incidence of dementia in England and Wales: findings from the five identical sites of the MRC CFA Study. PLoS Med. 2005, 2: e193-10.1371/journal.pmed.0020193.CrossRef
15.
go back to reference Bond J, Carstairs V: Scottish Health Service Studies. Services for the elderly. 1982, Edinburgh, Scottish Home and Health Department Bond J, Carstairs V: Scottish Health Service Studies. Services for the elderly. 1982, Edinburgh, Scottish Home and Health Department
16.
go back to reference Spiers NA, Matthews RJ, Jagger C, Matthews FE, Boult C, Robinson TG, Brayne C: Diseases and impairments as risk factors for onset of disability in the older population in England and Wales: findings from the Medical Research Council Cognitive Function and Ageing Study. J Gerontol A Biol Sci Med Sci. 2005, 60: 248-254.CrossRefPubMed Spiers NA, Matthews RJ, Jagger C, Matthews FE, Boult C, Robinson TG, Brayne C: Diseases and impairments as risk factors for onset of disability in the older population in England and Wales: findings from the Medical Research Council Cognitive Function and Ageing Study. J Gerontol A Biol Sci Med Sci. 2005, 60: 248-254.CrossRefPubMed
17.
go back to reference Copeland JR, Dewey ME, Griffiths-Jones HM: A computerized psychiatric diagnostic system and case nomenclature for elderly subjects: GMS and AGECAT. Psychol Med. 1986, 16: 89-99.CrossRefPubMed Copeland JR, Dewey ME, Griffiths-Jones HM: A computerized psychiatric diagnostic system and case nomenclature for elderly subjects: GMS and AGECAT. Psychol Med. 1986, 16: 89-99.CrossRefPubMed
18.
go back to reference Rose GA: The Diagnosis of Ischaemic Heart Pain and Intermittent Claudication in Field Surveys. Bulletin of the World Health Organisation. 1962, 27: 645-658. Rose GA: The Diagnosis of Ischaemic Heart Pain and Intermittent Claudication in Field Surveys. Bulletin of the World Health Organisation. 1962, 27: 645-658.
19.
go back to reference Unger JM, van Belle G, Heyman A: Cross-sectional versus longitudinal estimates of cognitive change in nondemented older people: a CERAD study. Consortium to Establish a Registry for Alzheimer's Disease. J Am Geriatr Soc. 1999, 47: 559-563.CrossRefPubMed Unger JM, van Belle G, Heyman A: Cross-sectional versus longitudinal estimates of cognitive change in nondemented older people: a CERAD study. Consortium to Establish a Registry for Alzheimer's Disease. J Am Geriatr Soc. 1999, 47: 559-563.CrossRefPubMed
20.
go back to reference Deeg DJ, van Tilburg T, Smit JH, de Leeuw ED: Attrition in the Longitudinal Aging Study Amsterdam. The effect of differential inclusion in side studies. J Clin Epidemiol. 2002, 55: 319-28. 10.1016/S0895-4356(01)00475-9.CrossRefPubMed Deeg DJ, van Tilburg T, Smit JH, de Leeuw ED: Attrition in the Longitudinal Aging Study Amsterdam. The effect of differential inclusion in side studies. J Clin Epidemiol. 2002, 55: 319-28. 10.1016/S0895-4356(01)00475-9.CrossRefPubMed
Metadata
Title
An investigation of whether factors associated with short-term attrition change or persist over ten years: data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
Authors
Fiona E Matthews
Mark Chatfield
Carol Brayne
Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
Publication date
01-12-2006
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2006
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-6-185

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